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Cédric Blanpain
Cédric Blanpain (born 6 September 1970) is a Belgian researcher in the field of stem cells (embryology, tissue homeostasis and cancer). He is a tenured professor of developmental biology and genetics at Université Libre de Bruxelles and director of the stem cell and cancer lab at its Faculty of Medicine. He was one of the first researchers in the world to use cell lineage tracing in cancer research and he showed for the first time the existence of cancer stem cells in solid tumors in vivo. He was selected by Nature as one of '' 10 People who mattered most in 2012'' and he received the outstanding young investigator award of the International Society for Stem Cell Research. Biography Born in Uccle in 1970. Cedric Blanpain attended Collège Saint-Hubert for his secondary education. Graduating in 1987, he started medical school with an aim of becoming a psychiatrist. As soon as his first year, he started doing research in human physiology at the Institut de Recherche Inter-Disci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature's 10
''Nature'' 10 is an annual listicle of ten "people who mattered" in science, produced by the scientific journal ''Nature''. Nominees have made a significant impact in science either for good or for bad. Reporters and editorial staff at ''Nature'' judge nominees to have had "a significant impact on the world, or their position in the world may have had an important impact on science". Short biographical profiles describe the people behind some of the year's most important discoveries and events. Alongside the ten, five "ones to watch" for the following year are also listed. 2022 2022 awardees included: # Jane Rigby: Sky hunter # Yunlong Cao: COVID predictor # Saleemul Huq: Climate revolutionary # Svitlana Krakovska: Voice for Ukraine # Dimie Ogoina: Monkeypox watchman # Lisa McCorkell: Long-COVID advocate # Diana Greene Foster: Abortion fact-finder # António Guterres: Crisis diplomat # Muhammad Mohiuddin: Transplant trailblazer # Alondra Nelson: Policy principal Ones to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uccle, Belgium
Uccle () or Ukkel () is one of the 19 municipalities of the Brussels-Capital Region, Belgium. In common with all of Brussels' municipalities, it is legally bilingual (French–Dutch). It is generally considered an affluent area of the city and is particularly noted for its community of French immigrants. History According to legend, Uccle's church of St. Peter was dedicated by Pope Leo III in the year 803, with Charlemagne and Gerbald, Bishop of Liège, attending the ceremony. During the following centuries, several noble families built their manors and took residency there. The first mention of the name ''Woluesdal'', now evolved into ''Wolvendael'', dates from 1209. In 1467, Isabella of Portugal, wife of Philip the Good, Duke of Burgundy, founded a Franciscan convent on Uccle's territory. Later, Uccle became the judiciary capital of the area including Brussels. Throughout the early stages of its history, however, the village of Uccle always had a predominantly rural charac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryonic development of animals are: tissue patterning (via regional specification and patterned cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing to a specific region or part of the organism. These are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marc Parmentier
Marc Parmentier (born 24 March 1956) is a Belgian scientist, and professor at the Institute of Multi-disciplinary Research in Human and Molecular Biology (IRIBHM) of the Université Libre de Bruxelles (ULB), where he completed his PhD in 1990. His research interest is on G protein-coupled receptors (GPCR), and of transgenic models of human pathologies. In 1999, he was awarded the Francqui Prize on Biological and Medical Sciences. Awards * 1985 - Marc Herlant prize * 1991 - Galien Prize of Pharmacology * 1993 - Belgian Endocrine Society Lecture * 1994 - Harrington De Vishere prize of the European Thyroid Association * 1997 - Merck Sharpe and Dohme Prize * 1998 - Liliane Bettencourt Prize * 1999 - Francqui Prize The Francqui Prize is a prestigious Belgian scholarly and scientific prize named after Émile Francqui. Normally annually since 1933, the Francqui Foundation awards it in recognition of the achievements of a scholar or scientist, who at the star ... Publications * Parme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Summa Cum Laude
Latin honors are a system of Latin phrases used in some colleges and universities to indicate the level of distinction with which an academic degree has been earned. The system is primarily used in the United States. It is also used in some Southeastern Asian countries with European colonial history, such as Indonesia and the Philippines, although sometimes translations of these phrases are used instead of the Latin originals. The honors distinction should not be confused with the honors degrees offered in some countries, or with honorary degrees. The system usually has three levels of honor: ''cum laude'', ''magna cum laude'', and ''summa cum laude''. Generally, a college or university's regulations set out definite criteria a student must meet to obtain a given honor. For example, the student might be required to achieve a specific grade point average, submit an honors thesis for evaluation, be part of an honors program, or graduate early. Each school sets its own standards. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gilbert Vassart
Gilbert Vassart is a Belgian scientist and professor at the Universite Libre de Bruxelles. His research interests include molecular endocrinology, especially related to the thyroid, and pharmacology of G protein-coupled receptor along with medical genetics. He is the past director of the ''Institut de Recherche Interdisciplinaire en Biologie humaine et moléculaire''IRIBHM and teaches Medical Genetics at the Medical School of the Université Libre de Bruxelles.G. Vassart Curriculum Vitae http://www.ae-info.org/attach/User/Vassart_Gilbert/CV/vassart_gilbert_long_cv.pdf Honors and awards * Docteur honoris causa of the University of Chicago (2002) * Docteur honoris causa of the Université René Descartes (2000) * Francqui Prize (1993) * Van Geysel European award for biomedical research (2000) * ISI Highly Cited The Institute for Scientific Information (ISI) was an academic publishing service, founded by Eugene Garfield in Philadelphia in 1956. ISI offered scientometric and bib ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uccle
Uccle () or Ukkel () is one of the 19 municipalities of the Brussels-Capital Region, Belgium. In common with all of Brussels' municipalities, it is legally bilingual (French–Dutch). It is generally considered an affluent area of the city and is particularly noted for its community of French immigrants. History According to legend, Uccle's church of St. Peter was dedicated by Pope Leo III in the year 803, with Charlemagne and Gerbald, Bishop of Liège, attending the ceremony. During the following centuries, several noble families built their manors and took residency there. The first mention of the name ''Woluesdal'', now evolved into ''Wolvendael'', dates from 1209. In 1467, Isabella of Portugal, wife of Philip the Good, Duke of Burgundy, founded a Franciscan convent on Uccle's territory. Later, Uccle became the judiciary capital of the area including Brussels. Throughout the early stages of its history, however, the village of Uccle always had a predominantly rural char ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 '' Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vivo
Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. This is not to be confused with experiments done ''in vitro'' ("within the glass"), i.e., in a laboratory environment using test tubes, Petri dishes, etc. Examples of investigations ''in vivo'' include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of ''in vivo'' research. ''In vivo'' testing is often employed over ''in vitro'' because it is better suited for observing the overall effects of an experiment on a living subject. In dr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Solid Tumors
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer Stem Cells
Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. CSCs are therefore tumorigenic (tumor-forming), perhaps in contrast to other non-tumorigenic cancer cells. CSCs may generate tumors through the stem cell processes of self-renewal and differentiation into multiple cell types. Such cells are hypothesized to persist in tumors as a distinct population and cause relapse and metastasis by giving rise to new tumors. Therefore, development of specific therapies targeted at CSCs holds hope for improvement of survival and quality of life of cancer patients, especially for patients with metastatic disease. Existing cancer treatments have mostly been developed based on animal models, where therapies able to promote tumor shrinkage were deemed effective. However, animals do not provide a complete ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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