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Co-incubation
In vitro fertilisation (IVF) is a process of fertilisation in which an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating the ovulatory process, then removing an ovum or ova (egg or eggs) from the ovaries and enabling sperm to fertilise them in a culture medium in a laboratory. After a fertilised egg (zygote) undergoes embryo culture for 2–6 days, it is transferred by catheter into the uterus, with the intention of establishing a successful pregnancy. IVF is a type of assisted reproductive technology used to treat infertility, enable gestational surrogacy, and, in combination with pre-implantation genetic testing, avoid the transmission of abnormal genetic conditions. When a fertilised egg from egg and sperm donors implants in the uterus of a genetically unrelated surrogate, the resulting child is also genetically unrelated to the surrogate. Some countries have banned or otherwise regulated the availability of IVF treatment ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embryo Culture
Embryo culture is a component of ''in vitro'' fertilisation where in resultant embryos are allowed to grow for some time in an artificial medium. Duration The duration of embryo culture can be varied, conferring different stages of embryogenesis at embryo transfer. The main stages at which embryo transfer is performed are cleavage stage (day 2 to 4 after co-incubation) or the blastocyst stage (day 5 or 6 after co-incubation). Embryos which reach the day 3 cell stage can be tested for chromosomal or specific genetic defects prior to possible transfer by preimplantation genetic diagnosis (PGD). Embryo culture until the blastocyst stage confers a significant increase in live birth rate per embryo transfer, and there is no evidence of a difference between the groups in cumulative pregnancy rates. Transfer day 2 instead of day 3 after fertilization has no differences in live birth rate. Monozygotic twinning is not increased after blastocyst transfer compared with cleavage-stage ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embryo Transfer
Embryo transfer refers to a step in the process of assisted reproduction in which embryos are placed into the uterus of a female with the intent to establish a pregnancy. This technique - which is often used in connection with in vitro fertilization (IVF) - may be used in humans or in other animals, in which situations and goals may vary. Embryo transfer can be done at day two or day three, or later in the blastocyst stage, which was first performed in 1984. Factors that can affect the success of embryo transfer include the endometrial receptivity, embryo quality, and embryo transfer technique. Fresh versus frozen Embryos can be either "fresh" from fertilized egg cells of the same menstrual cycle, or "frozen", that is they have been generated in a preceding cycle and undergone embryo cryopreservation, and are thawed just prior to the transfer, which is then termed "frozen embryo transfer" (FET). The outcome from using cryopreserved embryos has uniformly been positive wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pregnancy
Pregnancy is the time during which one or more offspring gestation, gestates inside a woman's uterus. A multiple birth, multiple pregnancy involves more than one offspring, such as with twins. Conception (biology), Conception usually occurs following sexual intercourse, vaginal intercourse, but can also occur through assisted reproductive technology procedures. A pregnancy may end in a Live birth (human), live birth, a miscarriage, an Abortion#Induced, induced abortion, or a stillbirth. Childbirth typically occurs around 40 weeks from the start of the Menstruation#Onset and frequency, last menstrual period (LMP), a span known as the Gestational age (obstetrics), ''gestational age''; this is just over nine months. Counting by Human fertilization#Fertilization age, ''fertilization age'', the length is about 38 weeks. Implantation (embryology), Implantation occurs on average 8–9 days after Human fertilization, fertilization. An ''embryo'' is the term for the deve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FOREIGN
Foreign may refer to: Government * Foreign policy, how a country interacts with other countries * Ministry of Foreign Affairs, in many countries ** Foreign Office, a department of the UK government ** Foreign office and foreign minister * United States State law (United States), state law, a legal matter in another state Science and technology * Foreign accent syndrome, a side effect of severe brain injury * Foreign key, a constraint in a relational database Arts and entertainment * Foreign film or world cinema, films and film industries of non-English-speaking countries * Foreign music or world music * Foreign literature or world literature * ''Foreign Policy'', a magazine Music * "Foreign", a song by Jessica Mauboy from her 2010 album ''Get 'Em Girls'' * Foreign (Trey Songz song), "Foreign" (Trey Songz song), 2014 * "Foreign", a song by Lil Pump from the album ''Lil Pump (album), Lil Pump'' Other uses * Foreign corporation, a corporation that can do business outside its jurisd ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royton
Royton is a town in the Metropolitan Borough of Oldham, Greater Manchester, England, with a population of 21,284 in 2011. Close to the source of the River Irk, near undulating land at the foothills of the South Pennines, it is northwest of Oldham, southeast of Rochdale and northeast of Manchester. Within the boundaries of the Historic counties of England, historic county of Lancashire, Royton and its surroundings have provided evidence of Britons (historic), ancient British, Roman Britain, Roman and Viking activity in the area.. During the Middle Ages, Royton formed a small Township (England), township centred on Royton Hall, a manor house owned by a long succession of dignitaries which included the Baron Byron, Byrons and Radcliffe Baronets, Radcliffes. A settlement expanded outwards from the hall which, by as late as 1780, "contained only a few straggling and mean-built cottages". Farming was the main industry of this rural area, with locals supplementing their incomes by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Implantation (embryology)
Implantation, also known as nidation, is the stage in the mammalian embryonic development in which the blastocyst hatches, attaches, adheres, and penetrates into the endometrium of the female's uterus. Implantation is the first stage of gestation, and, when successful, the female is considered to be pregnant. An implanted embryo is detected by the presence of increased levels of human chorionic gonadotropin (hCG) in a pregnancy test. The implanted embryo will receive oxygen and nutrients in order to grow. For implantation to take place the uterus must become receptive. Uterine receptivity involves much cross-talk between the embryo and the uterus, initiating changes to the endometrium. This stage gives a synchrony that opens a window of implantation that enables successful implantation of a viable embryo. The endocannabinoid system plays a vital role in this synchrony in the uterus, influencing uterine receptivity, and embryo implantation. The embryo expresses cannabinoid r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fertility Tourism
Fertility tourism (also referred to as reproductive tourism or cross border reproductive care) is the practice of traveling to another country or jurisdiction for assisted reproductive technology, fertility treatment, and may be regarded as a form of medical tourism. A person who can become pregnant is considered to have fertility issues if they are unable to have a clinical pregnancy after 12 months of unprotected intercourse. Infertility, or the inability to get pregnant, affects about 8-12% of couples looking to conceive or 186 million people globally. In some places, rates of infertility surpass the global average and can go up to 30% depending on the country. Areas with lack of resources, such as Assisted reproductive technology, assisted reproductive technologies (ARTs), tend to correlate with the highest rates of infertility. The main procedures sought are in vitro fertilization (IVF), artificial insemination by a donor, as well as surrogacy. These methods are types of assi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louise Brown
Louise Joy Brown (born 25 July 1978) is an English woman noted as the first human born following conception by in vitro fertilisation (IVF). Her birth, following a procedure pioneered in Britain, has been lauded among "the most remarkable medical breakthroughs of the 20th century". Life Brown's parents, Lesley and John Brown, had been trying to conceive naturally for nine years but Lesley faced complications from blocked fallopian tubes."World's first IVF baby marks 30th birthday" , 23 July 2008. Retrieved 24 July 2008. On 10 November 1977, Lesley underwent the procedure that later became known as |
Robert Edwards (physiologist)
Sir Robert Geoffrey Edwards (27 September 1925 – 10 April 2013) was a British physiologist and pioneer in reproductive medicine, and in-vitro fertilisation (IVF) in particular. Along with obstetrician and gynaecologist Patrick Steptoe and nurse and embryologist Jean Purdy, Edwards successfully pioneered conception through IVF, which led to the birth of Louise Joy Brown, Louise Brown on 1978. They founded the first IVF programme for infertile patients and trained other scientists in their techniques. Edwards was the founding editor-in-chief of ''Human Reproduction (journal), Human Reproduction'' in 1986. In 2010, he was awarded the Nobel Prize in Physiology or Medicine "for the development of in vitro fertilization". Education and early career Edwards was born in Batley, Yorkshire, and attended Manchester Academy (Moss Side), Manchester Central High School on Whitworth Street in central Manchester, after which he served in the British Army, and then completed his undergra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gestational Surrogacy
Surrogacy is an arrangement whereby a woman gets pregnant and gives birth on behalf of another person or couple who will become the child's legal parents after birth. People pursue surrogacy for a variety of reasons such as infertility, dangers or undesirable factors of pregnancy, or when pregnancy is a medical impossibility. Surrogacy is highly controversial and only legal in twelve countries. A surrogacy relationship or legal agreement contains the person who carries the pregnancy and gives birth and the person or persons who take custody of the child after birth. The person giving birth is called the birth mother or gestational carrier or surrogate mother or surrogate. Those taking custody are called the ''commissioning'' or ''intended'' parents. The biological mother may be the surrogate or the intended parent or neither. Surrogate mothers are usually introduced to intended parents through third-party agencies, or other matching channels. They are usually required to par ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine () is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Medicine or Physiology, Chemistry, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2024, 115 Nobel Prizes in Physiology or Medicine have been awarded to 229 laureates, 216 men and 13 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucida ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Geoffrey Edwards
Sir Robert Geoffrey Edwards (27 September 1925 – 10 April 2013) was a British physiologist and pioneer in reproductive medicine, and in-vitro fertilisation (IVF) in particular. Along with obstetrician and gynaecologist Patrick Steptoe and nurse and embryologist Jean Purdy, Edwards successfully pioneered conception through IVF, which led to the birth of Louise Brown on 1978. They founded the first IVF programme for infertile patients and trained other scientists in their techniques. Edwards was the founding editor-in-chief of '' Human Reproduction'' in 1986. In 2010, he was awarded the Nobel Prize in Physiology or Medicine "for the development of in vitro fertilization". Education and early career Edwards was born in Batley, Yorkshire, and attended Manchester Central High School on Whitworth Street in central Manchester, after which he served in the British Army, and then completed his undergraduate studies in biology, graduating with an ordinary degree from Bango ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
