|
Clostridia
The Clostridia are a highly polyphyletic class of Bacillota, including '' Clostridium'' and other similar genera. They are distinguished from the Bacilli by lacking aerobic respiration. They are obligate anaerobes and oxygen is toxic to them. Species of the class Clostridia are often but not always Gram-positive (see '' Halanaerobium'') and have the ability to form spores. Studies show they are not a monophyletic group, and their relationships are not entirely certain. Currently, most are placed in a single order called Clostridiales, but this is not a natural group and is likely to be redefined in the future. Most species of the genus ''Clostridium'' are saprophytic organisms that ferment plant polysaccharides and are found in many places in the environment, most notably the soil. However, the genus does contain some human pathogens (outlined below). The toxins produced by certain members of the genus ''Clostridium'' are among the most dangerous known. Examples are tetan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clostridium
''Clostridium'' is a genus of anaerobic, Gram-positive bacteria. Species of ''Clostridium'' inhabit soils and the intestinal tracts of animals, including humans. This genus includes several significant human pathogens, including the causative agents of botulism and tetanus. It also formerly included an important cause of diarrhea, '' Clostridioides difficile'', which was reclassified into the '' Clostridioides'' genus in 2016. History In the late 1700s, Germany experienced several outbreaks of an illness connected to eating specific sausages. In 1817, the German neurologist Justinus Kerner detected rod-shaped cells in his investigations into this so-called sausage poisoning. In 1897, the Belgian biology professor Emile van Ermengem published his finding of an endospore-forming organism he isolated from spoiled ham. Biologists classified van Ermengem's discovery along with other known gram-positive spore formers in the genus ''Bacillus''. This classification presented proble ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacillota
The Bacillota (synonym Firmicutes) are a phylum of bacteria, most of which have Gram-positive cell wall structure. They have round cells, called cocci (singular coccus), or rod-like forms (bacillus). A few Bacillota, such as '' Megasphaera'', '' Pectinatus'', '' Selenomonas'', and '' Zymophilus'' from the class Negativicutes, have a porous pseudo-outer membrane that causes them to stain Gram-negative. Many Bacillota produce endospores, which are resistant to desiccation and can survive extreme conditions. They are found in various environments, and the group includes some notable pathogens. Those in one family, the Heliobacteria, produce energy through anoxygenic photosynthesis. Bacillota play an important role in beer, wine, and cider spoilage. Taxonomy The renaming of phyla such as Firmicutes in 2021 remains controversial among microbiologists, many of whom continue to use the earlier names of long standing in the literature. The name "Firmicutes" was derived from the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clostridium Perfringens
''Clostridium perfringens'' (formerly known as ''C. welchii'', or ''Bacillus welchii'') is a Gram-positive, bacillus (rod-shaped), anaerobic, spore-forming pathogenic bacterium of the genus '' Clostridium''. ''C. perfringens'' is ever-present in nature and can be found as a normal component of decaying vegetation, marine sediment, the intestinal tract of humans and other vertebrates, insects, and soil. It has the shortest reported generation time of any organism at 6.3 minutes in thioglycolate medium. ''Clostridium perfringens'' is one of the most common causes of food poisoning in the United States, alongside norovirus, ''Salmonella'', '' Campylobacter'', and ''Staphylococcus aureus''. However, it can sometimes be ingested and cause no harm. Infections induced by ''C. perfringens'' are associated with tissue necrosis, bacteremia, emphysematous cholecystitis, and gas gangrene, which is also known as clostridial myonecrosis. The specific name, ''perfringens,'' is derived ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clostridiales
The Eubacteriales are an order of bacteria placed within the class Clostridia. Phylogeny The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI) External phylogeny Unassigned families: * " Betainaceae" Jones et al. 2019 * " Darwinibacteraceae" Puchol-Royo et al. 2023 * " Wallacebacteraceae" Puchol-Royo et al. 2023 See also * List of bacterial orders * List of bacteria genera This article lists the genera of the bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, ... References Bacteria orders Long stubs with short prose {{clostridia-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eubacteriales
The Eubacteriales are an order of bacteria placed within the class Clostridia. Phylogeny The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI) External phylogeny Unassigned families: * " Betainaceae" Jones et al. 2019 * " Darwinibacteraceae" Puchol-Royo et al. 2023 * " Wallacebacteraceae" Puchol-Royo et al. 2023 See also * List of bacterial orders * List of bacteria genera This article lists the genera of the bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, ... References Bacteria orders Long stubs with short prose {{clostridia-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thermoanaerobacterales
The Thermoanaerobacterales is a polyphyletic order (biology), order of bacteria placed within the polyphyletic class (taxonomy), class Clostridia, and encompassing four families: the Thermoanaerobacteraceae, the Thermodesulfobiaceae, the Thermoanaerobacterales Family III. Incertae Sedis, and the Thermoanaerobacterales Family IV. Incertae Sedis, and various unplaced genera. This order is noted for the species' abilities to survive in extreme environments without oxygen and of relatively elevated temperatures for a living being (up to 80-90 °C). An example organism in this order is ''Thermoanaerobacter ethanolicus''.C.Michael Hogan. 2010''Extremophile''. eds. E.Monosson & C.Cleveland, Encyclopedia of Earth. National Council for Science and the Environment, Washington DC./ref> Taxonomy The Thermoanaerobacterales, as previously mentioned, is polyphyletic, and consists of numerous morphologically similar clades: Phylogeny Note: * polyphyletic Thermoanaerobacterales See also ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clostridium Botulinum
''Clostridium botulinum'' is a Gram-positive bacteria, gram-positive, Bacillus (shape), rod-shaped, Anaerobic organism, anaerobic, endospore, spore-forming, Motility, motile bacterium with the ability to produce botulinum toxin, which is a neurotoxin. ''C. botulinum'' is a diverse group of pathogenic bacteria. Initially, they were grouped together by their ability to produce botulinum toxin and are now known as four distinct groups, ''C. botulinum'' groups I–IV. Along with some strains of ''Clostridium butyricum'' and ''Clostridium baratii'', these bacteria all produce the toxin. Botulinum toxin can cause botulism, a severe Flaccid paralysis, flaccid paralytic disease in humans and other animals, and is the most potent toxin known to science, natural or synthetic, with a lethal dose of 1.3–2.1 ng/kg in humans.(2010). Chapter 19. ''Clostridium'', ''Peptostreptococcus'', ''Bacteroides'', and Other Anaerobes. In Ryan K.J., Ray C (Eds), ''Sherris Medical Microbiology'', 5th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetanospasmin
Tetanus toxin (TeNT) is an extremely potent neurotoxin produced by the vegetative cell of '' Clostridium tetani'' in anaerobic conditions, causing tetanus. It has no known function for clostridia in the soil environment where they are normally encountered. It is also called spasmogenic toxin, tentoxilysin, tetanospasmin, or tetanus neurotoxin. The LD50 of this toxin has been measured to be approximately 2.5–3 ng/kg, making it second only to the related botulinum toxin (LD50 2 ng/kg) as the deadliest toxin in the world. However, these tests are conducted solely on mice, which may react to the toxin differently from humans and other animals. ''C. tetani'' also produces the exotoxin tetanolysin, a hemolysin, that causes destruction of tissues. Distribution Tetanus toxin spreads through tissue spaces into the lymphatic and vascular systems. It enters the nervous system at the neuromuscular junctions and migrates through nerve trunks and into the central nervo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Halanaerobium
''Halanaerobium'' is a gram-negative, non-endospore-forming, rod-shaped, and strictly anaerobic genus of bacteria from the family Halanaerobiaceae. Phylogeny The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI). See also * List of bacterial orders * List of bacteria genera This article lists the genera of the bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, ... References Clostridia Bacteria genera Taxa described in 1984 {{Bacillota-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Obligate Anaerobe
Obligate anaerobes are microorganisms killed by normal Atmosphere of Earth, atmospheric concentrations of oxygen (20.95% O2). Oxygen tolerance varies between species, with some species capable of surviving in up to 8% oxygen, while others lose viability in environments with an oxygen concentration greater than 0.5%. Oxygen sensitivity The oxygen sensitivity of obligate anaerobes has been attributed to a combination of factors including oxidative stress and enzyme production. Oxygen can also damage obligate anaerobes in ways not involving oxidative stress. Because molecular Triplet oxygen, oxygen contains two unpaired electrons in the HOMO and LUMO, highest occupied molecular orbital, it is readily reduced to superoxide () and hydrogen peroxide () within cells. A reaction between these two products results in the formation of a free hydroxyl radical (OH.). Superoxide, hydrogen peroxide, and hydroxyl radicals are a class of compounds known as reactive oxygen species (ROS), highly r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food Poisoning
Foodborne illness (also known as foodborne disease and food poisoning) is any illness resulting from the contamination of food by pathogenic bacteria, viruses, or parasites, as well as prions (the agents of mad cow disease), and toxins such as aflatoxins in peanuts, poisonous mushrooms, and various species of beans that have not been boiled for at least 10 minutes. While contaminants directly cause some symptoms, many effects of foodborne illness result from the body's immune response to these agents, which can vary significantly between individuals and populations based on prior exposure. Symptoms vary depending on the cause. They often include vomiting, fever, aches, and diarrhea. Bouts of vomiting can be repeated with an extended delay in between. This is because even if infected food was eliminated from the stomach in the first bout, microbes, like bacteria (if applicable), can pass through the stomach into the intestine and begin to multiply. Some types of microbes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
