Carl-Henry Alström
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Carl-Henry Alström
Carl-Henry Alström (3 May 1907 – December 31, 1993) was a Swedish psychiatrist who described a syndrome now named for him, Alström syndrome, a hereditary disorder that characteristically includes obesity in childhood, nerve deafness, and retinal degeneration (due to atypical retinitis pigmentosa Retinitis pigmentosa (RP) is a member of a group of genetic disorders called inherited retinal dystrophy (IRD) that cause loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visua ...).Alstrom C. H., Hallgren B., Nilsson L. B., Asander H. (1959) "Retinal degeneration combined with obesity, diabetes mellitus and neurogenous deafness: a specific syndrome (not hitherto described) distinct from the Laurence-Moon-Bardet-Biedl syndrome: a clinical, endocrinological and genetic examination based on a large pedigree." Acta Psychiatr Neurol Scand Suppl. 129:1-35 External linksCarl-Henry Alströmbiographical sketch oWho Named ...
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Västerås
Västerås () is a city in central Sweden on the shore of Mälaren, Lake Mälaren in the province of Västmanland, west of Stockholm. The city had a population of 127,799 at the end of 2019, out of the municipal total of 158,653, over 100,000 more than the next largest of the 17 localities included in the Västerås Municipality. Västerås is the seat of Västerås Municipality, which is the capital of Västmanland County and an episcopal see. History Västerås is one of the oldest cities in Sweden and Northern Europe. The area has been populated since the Nordic Viking Age, before 1000 CE. Anundshög, Sweden's largest burial mound, is located just outside the City of Västerås. It was built about 500 CE and is over wide and is almost high. In the beginning of the 11th century, Västerås was the second largest city in Sweden; by the 12th century, it had become the seat of the bishop. The name ''Västerås'' originates from ''Västra Aros'' (), first recorded as ''Westra ...
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Karolinska Institute
The Karolinska Institute (KI; ; sometimes known as the (Royal) Caroline Institute in English) is a research-led medical university in Solna within the Stockholm urban area of Sweden and one of the foremost medical research institutes globally. The Nobel Assembly at the Karolinska Institute awards the Nobel Prize in Physiology or Medicine. The assembly consists of fifty professors from various medical disciplines at the university. The current vice-chancellor of Karolinska Institute is Annika Östman Wernerson, who took office in March 2023. The Karolinska Institute was founded in 1810 on the island of Kungsholmen on the west side of Stockholm; the main campus was relocated decades later to Solna, just outside Stockholm. A second campus was established more recently in Flemingsberg, Huddinge, south of Stockholm. The institute also has a Centre for Reparative Medicine, consisting of two nodes, one in Stockholm and one in Hong Kong. The Karolinska Institute is Sweden's thir ...
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Alström Syndrome
Alström syndrome (AS), also called Alström–Hallgren syndrome, is a very rare autosomal recessive genetic disorder characterised by childhood obesity and multiple organ dysfunction. Symptoms include early-onset type 2 diabetes, cone-rod dystrophy resulting in blindness, sensorineural hearing loss and dilated cardiomyopathy. Endocrine disorders typically also occur, such as hypergonadotrophic hypogonadism and hypothyroidism, as well as acanthosis nigricans resulting from hyperinsulinemia. Developmental delay is seen in almost half of people with Alström syndrome. It is caused by mutations in the gene '' ALMS1'', which is involved in the formation of cellular cilia, making Alström syndrome a ciliopathy. At least 239 disease-causing mutations in ''ALMS1'' have been described . Alström syndrome is sometimes confused with Bardet–Biedl syndrome, another ciliopathy which has similar symptoms, but Bardet–Biedl syndrome tends to have later onset in its symptoms, includ ...
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Sweden
Sweden, formally the Kingdom of Sweden, is a Nordic countries, Nordic country located on the Scandinavian Peninsula in Northern Europe. It borders Norway to the west and north, and Finland to the east. At , Sweden is the largest Nordic country by both area and population, and is the List of European countries by area, fifth-largest country in Europe. Its capital and largest city is Stockholm. Sweden has a population of 10.6 million, and a low population density of ; 88% of Swedes reside in urban areas. They are mostly in the central and southern half of the country. Sweden's urban areas together cover 1.5% of its land area. Sweden has a diverse Climate of Sweden, climate owing to the length of the country, which ranges from 55th parallel north, 55°N to 69th parallel north, 69°N. Sweden has been inhabited since Prehistoric Sweden, prehistoric times around 12,000 BC. The inhabitants emerged as the Geats () and Swedes (tribe), Swedes (), who formed part of the sea-faring peopl ...
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Psychiatrist
A psychiatrist is a physician who specializes in psychiatry. Psychiatrists are physicians who evaluate patients to determine whether their symptoms are the result of a physical illness, a combination of physical and mental ailments or strictly mental issues. Sometimes a psychiatrist works within a multi-disciplinary team, which may comprise clinical psychologists, social workers, occupational therapists, and nursing staff. Psychiatrists have broad training in a biopsychosocial approach to the assessment and management of mental illness. As part of the clinical assessment process, psychiatrists may employ a mental status examination; a physical examination; brain imaging such as a computerized tomography, magnetic resonance imaging, or positron emission tomography scan; and blood testing. Psychiatrists use pharmacologic, psychotherapeutic, or interventional approaches to treat mental disorders. Subspecialties The field of psychiatry has many subspecialties that ...
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Obesity
Obesity is a medical condition, considered by multiple organizations to be a disease, in which excess Adipose tissue, body fat has accumulated to such an extent that it can potentially have negative effects on health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over ; the range is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is Obesity-associated morbidity, correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity has individual, socioeconomic, and environmental causes. Some known causes are Western pattern diet, diet, low physical activity, automation, urbanization, quantitative trait locus, genetic susceptibility, medications, mental disorders, Economic policy, economic pol ...
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Deafness
Deafness has varying definitions in cultural and medical contexts. In medical contexts, the meaning of deafness is hearing loss that precludes a person from understanding spoken language, an audiological condition. In this context it is written with a lower case ''d''. It later came to be used in a cultural context to refer to those who primarily communicate with a deafness aid or through sign language regardless of hearing ability, often capitalized as ''Deaf'' and referred to as "big D Deaf" in speech and sign. The two definitions overlap but are not identical, as hearing loss includes cases that are not severe enough to impact spoken language comprehension, while cultural Deafness includes hearing people who use sign language, such as children of deaf adults. Medical context In a medical context, deafness is defined as a degree of hearing difficulties such that a person is unable to understand speech, even in the presence of amplification. In profound deafness, eve ...
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Retinitis Pigmentosa
Retinitis pigmentosa (RP) is a member of a group of genetic disorders called inherited retinal dystrophy (IRD) that cause loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visual field). As peripheral vision worsens, people may experience " tunnel vision". Complete blindness is uncommon. Onset of symptoms is generally gradual and often begins in childhood. Retinitis pigmentosa is generally inherited from one or both parents. It is caused by genetic variants in nearly 100 genes. The underlying mechanism involves the progressive loss of rod photoreceptor cells that line the retina of the eyeball. The rod cells secrete a neuroprotective substance (rod-derived cone viability factor, RdCVF) that protects the cone cells from apoptosis. When these rod cells die, this substance is no longer provided. This is generally followed by the loss of cone photoreceptor cells. Diagnosis is through eye examination of the retina ...
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1907 Births
Events January * January 14 – 1907 Kingston earthquake: A 6.5 Mw earthquake in Kingston, Jamaica, kills between 800 and 1,000. February * February 9 – The " Mud March", the first large procession organised by The National Union of Women's Suffrage Societies ( NUWSS), takes place in London. * February 11 – The French warship ''Jean Bart'' sinks off the coast of Morocco. * February 12 – The steamship ''Larchmont'' collides with the ''Harry Hamilton'' in Long Island Sound; 183 lives are lost. * February 16 – SKF, a worldwide mechanical parts manufacturing brand (mainly, bearings and seals), is founded in Gothenburg, Sweden. * February 21 – The English mail steamship ''Berlin'' is wrecked off the Hook of Holland; 142 lives are lost. * February 24 – The Austrian Lloyd steamship ''Imperatrix'', from Trieste to Bombay, is wrecked on Cape of Crete and sinks; 137 lives are lost. March * March ** The steamship ''Congo'' collide ...
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1993 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ...
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Swedish Psychiatrists
Swedish or ' may refer to: Anything from or related to Sweden, a country in Northern Europe. Or, specifically: * Swedish language, a North Germanic language spoken primarily in Sweden and Finland ** Swedish alphabet, the official alphabet used by the Swedish language * Swedish people or Swedes, persons with a Swedish ancestral or ethnic identity ** A national or citizen of Sweden, see demographics of Sweden ** Culture of Sweden * Swedish cuisine See also * * Swedish Church (other) * Swedish Institute (other) * Swedish invasion (other) * Swedish Open (other) Swedish Open is a tennis tournament. Swedish Open may also refer to: * Swedish Open (badminton) * Swedish Open (table tennis) * Swedish Open (squash) * Swedish Open (darts) {{disambiguation ... {{disambig Language and nationality disambiguation pages ...
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