CURB65
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CURB65
CURB-65, also known as the CURB criteria, is a clinical prediction rule that has been validated for predicting mortality in community-acquired pneumonia and infection of any site. The CURB-65 is based on the earlier CURB score and is recommended by the British Thoracic Society for the assessment of severity of pneumonia. It was developed in 2002 at the University of Nottingham by Dr. W.S. Lim et al. In 2018 a new toolkit was presented on the basis of CURB-65. The score is an acronym for each of the risk factors measured. Each risk factor scores one point, for a maximum score of 5: * Confusion of new onset (defined as an AMTS of 8 or less) * Blood Urea nitrogen greater than 7 mmol/L (19 mg/dL) * Respiratory rate of 30 breaths per minute or greater * Blood pressure less than 90 mmHg systolic or diastolic blood pressure 60 mmHg or less * Age 65 or older Predicting death Pneumonia The risk of death at 30 days increases as the score increases: * 0—0.7% * 1—3.2% * 2— ...
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Clinical Prediction Rule
A clinical prediction rule or clinical probability assessment specifies how to use medical signs, symptoms, and other findings to estimate the probability of a specific disease or clinical outcome. Physicians have difficulty in estimated risks of diseases; frequently erring towards overestimation, perhaps due to cognitive biases such as base rate fallacy in which the risk of an adverse outcome is exaggerated. Methods In a prediction rule study, investigators identify a consecutive group of patients who are suspected of having a specific disease or outcome. The investigators then obtain a standard set of clinical observations on each patient and a test or clinical follow-up to define the true state of the patient. They then use statistical methods to identify the best clinical predictors of the patient's true state. The probability of disease will depend on the patient's key clinical predictors. Published methodological standards specify good practices for developing a clinical p ...
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Community-acquired Pneumonia
Community-acquired pneumonia (CAP) refers to pneumonia contracted by a person outside of the healthcare system. In contrast, hospital-acquired pneumonia (HAP) is seen in patients who are in a hospital or who have recently been hospitalized in the last 48 hours. Those who live in long-term care facilities or who had pneumonia after 48 hours of hospitalization for another cause are also classified as having CAP (they were previously designated as having HCAP (healthcare associated pneumonia)). CAP is common, affecting people of all ages, and its symptoms occur as a result of oxygen-absorbing areas of the lung ( alveoli) becoming colonized by a pathogenic microorganism (such as bacteria, viruses or fungi). The resulting inflammation and tissue damage causes fluid to fill the alveoli, inhibiting lung function and causing the symptoms of the disease. Common symptoms of CAP include dyspnea, fever, chest pains and cough. 10% of those with CAP are hospitalized. The 30 day mortality for tho ...
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British Thoracic Society
The British Thoracic Society (BTS) was formed in 1982 by the amalgamation of the British Thoracic Association and the Thoracic Society. It is a registered charity and a company limited by guarantee. Function The Society's main charitable objective is to improve the care of people with respiratory disorders, which it aims to achieve by: * promoting optimum standards of care (the website contains treatment Guidelines, good practice guides and related audit tools) * promoting and advancing knowledge about the causes, prevention and treatment of respiratory diseases (the Society runs two large conferences each year and a range of short courses) * promoting and disseminating research (the Society's Winter Meeting is the main showcase for this activity, as well as the journal Thorax, published jointly with the British Medical Journal, and thRespiratory Futureswebsite). Structure BTS is a membership organisation, with over 4,700 members from the respiratory health sector (). These in ...
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University Of Nottingham
The University of Nottingham is a public research university in Nottingham, England. It was founded as University College Nottingham in 1881, and was granted a royal charter in 1948. Nottingham's main campus (University Park Campus, Nottingham, University Park) with Jubilee Campus and teaching hospital (Queen's Medical Centre) are located within the City of Nottingham, with a number of smaller campuses and sites elsewhere in Nottinghamshire and Derbyshire. Outside the UK, the university has campuses in Semenyih, Malaysia, and Ningbo, China. Nottingham is organised into five constituent faculties, within which there are more than 50 schools, departments, institutes and research centres. Nottingham has more than 46,000 students and 7,000 staff across the UK, China and Malaysia and had an income of £834.7 million in 2023–24, of which £141.6 million was from research grants and contracts, with an expenditure of £615.3 million. The institution's alumni have been awarded one ...
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Acronym
An acronym is a type of abbreviation consisting of a phrase whose only pronounced elements are the initial letters or initial sounds of words inside that phrase. Acronyms are often spelled with the initial Letter (alphabet), letter of each word in all caps with no punctuation. For some, an initialism or alphabetism connotes this general meaning, and an ''acronym'' is a subset with a narrower definition; an acronym is pronounced as a word rather than as a sequence of letters. In this sense, ''NASA'' () is an acronym, but ''United States, USA'' () is not. The broader sense of ''acronym'', ignoring pronunciation, is its original meaning and in common use. . Dictionary and style-guide editors dispute whether the term ''acronym'' can be legitimately applied to abbreviations which are not pronounced as words, and they do not agree on acronym space (punctuation), spacing, letter case, casing, and punctuation. The phrase that the acronym stands for is called its . The of an acron ...
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Abbreviated Mental Test Score
The Abbreviated Mental Test Score (AMTS) is a 10-point test designed for the rapid assessment of elderly patients for potential dementia. It is recommended as the primary screening tool in emergency and hospital settings for patients over 65. First introduced in 1972, it is now also utilized to assess mental confusion (including delirium) and other cognitive impairments. The test takes approximately 34 minutes to administer and requires no specialist training or licensing. History The AMTS was developed to address the need for a rapid, practical method of assessing cognitive impairment in geriatric patients. In 1972, Hodkinson adapted it from the 26-item Blessed Dementia Scale (BDS) by removing 16 items: 13 for repetitiveness, 2 for being too easy, and 1 for being too difficult. Validation studies revealed a near-linear correlation between AMTS and BDS scores, indicating strong convergent validity and measurement accuracy. Questionnaire and scoring The standard AMTS consist ...
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Pneumonia Severity Index
The pneumonia severity index (PSI) or PORT Score is a clinical prediction rule that medical practitioners can use to calculate the probability of morbidity and mortality among patients with community acquired pneumonia. The PSI/PORT score is often used to predict the need for hospitalization in people with pneumonia. This is consistent with the conclusions stated in the original report that published the PSI/PORT score: "The prediction rule we describe accurately identifies the patients with community-acquired pneumonia who are at low risk for death and other adverse outcomes. This prediction rule may help physicians make more rational decisions about hospitalization for patients with pneumonia." Mortality prediction is similar to that when using CURB-65. Development The rule uses demographics (whether someone is older, and is male or female), the coexistence of co-morbid illnesses, findings on physical examination and vital signs, and essential laboratory findings. This stud ...
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Diagnostic Intensive Care Medicine
Diagnosis (: diagnoses) is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in a lot of different disciplines, with variations in the use of logic, analytics, and experience, to determine " cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions. Computer science and networking * Bayesian network * Complex event processing * Diagnosis (artificial intelligence) * Event correlation * Fault management * Fault tree analysis * Grey problem * RPR problem diagnosis * Remote diagnostics * Root cause analysis * Troubleshooting * Unified Diagnostic Services Mathematics and logic * Bayesian probability * Block Hackam's dictum * Occam's razor * Regression diagnostics * Sutton's law Medicine * Medical diagnosis * Molecular diagnostics Methods * CDR computerized assessment system * Computer-aided diagnosis * Differential diagnosis * Retrospective ...
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Medical Scales
Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healin ...
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Science And Technology In Nottinghamshire
Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which study the physical world, and the social sciences, which study individuals and societies. While referred to as the formal sciences, the study of logic, mathematics, and theoretical computer science are typically regarded as separate because they rely on deductive reasoning instead of the scientific method as their main methodology. Meanwhile, applied sciences are disciplines that use scientific knowledge for practical purposes, such as engineering and medicine. The history of science spans the majority of the historical record, with the earliest identifiable predecessors to modern science dating to the Bronze Age in Ancient Egypt, Egypt and Mesopotamia (). Their contributions to mathematics, astronomy, and medicine entered and shaped the Gree ...
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