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Benno Müller-Hill
Benno Müller-Hill (5 February 1933 – 11 August 2018) was a German biologist and author. Together with Walter Gilbert, Müller-Hill purified the lac repressor The ''lac'' repressor (LacI) is a DNA-binding protein that inhibits the expression of genes coding for proteins involved in the metabolism of lactose in bacteria. These genes are repressed when lactose is not available to the cell, ensuring th ..., the first genetic control protein to be isolated. Müller-Hill has lectured widely and written books on the misuse of science by the Nazis. He was a professor of Genetics at the University of Cologne. He wrote several journal articles including 'Genetics of susceptibility to tuberculosis: Mengele's experiments in Auschwitz' (2001) and 'The blood from Auschwitz and the silence of the scholars' (1999). He also wrote Murderous Science: Elimination by Scientific Selection of Jews, Gypsies, and Others, Germany 1933-1945. It "is a devastating indictment of the role German s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Walter Gilbert
Walter Gilbert (born March 21, 1932) is an American biochemist, physicist, molecular biology pioneer, and Nobel laureate. Education and early life Walter Gilbert was born in Boston, Massachusetts, on March 21, 1932, the son of Emma (Cohen), a child psychologist, and Richard V. Gilbert, an economist. When Gilbert was seven years old, the family moved to the Washington D.C. area so his father could work under Harry Hopkins on the New Deal brain trust. While living in Washington the family became friends with the family of I.F. Stone and Wally met Stone's oldest daughter, Celia, when they were both 8. They later married at age 21. He was educated at the Sidwell Friends School, and attended Harvard University for undergraduate and graduate studies, earning a baccalaureate in chemistry and physics in 1953 and a master's degree in physics in 1954. He studied for his doctorate at the University of Cambridge, where he earned a PhD in physics supervised by the Nobel laureate Abdus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lac Repressor
The ''lac'' repressor (LacI) is a DNA-binding protein that inhibits the expression of genes coding for proteins involved in the metabolism of lactose in bacteria. These genes are repressed when lactose is not available to the cell, ensuring that the bacterium only invests energy in the production of machinery necessary for uptake and utilization of lactose when lactose is present. When lactose becomes available, it is firstly converted into allolactose by β-Galactosidase (lacZ) in bacteria. The DNA binding ability of lac repressor bound with allolactose is inhibited due to allosteric regulation, thereby genes coding for proteins involved in lactose uptake and utilization can be expressed. Function The ''lac'' repressor (LacI) operates by a helix-turn-helix motif in its DNA-binding domain, binding base-specifically to the major groove of the operator region of the ''lac'' operon, with base contacts also made by residues of symmetry-related alpha helices, the "hinge" heli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1933 Births
Events January * January 11 – Sir Charles Kingsford Smith makes the first commercial flight between Australia and New Zealand. * January 17 – The United States Congress votes in favour of Philippines independence, against the wishes of U.S. President Herbert Hoover. * January 28 – "Pakistan Declaration": Choudhry Rahmat Ali publishes (in Cambridge, UK) a pamphlet entitled ''Now or Never; Are We to Live or Perish Forever?'', in which he calls for the creation of a Muslim state in northwest India that he calls " Pakstan"; this influences the Pakistan Movement. * January 30 ** National Socialist German Workers Party leader Adolf Hitler is appointed Chancellor of Germany by President of Germany Paul von Hindenburg. ** Édouard Daladier forms a government in France in succession to Joseph Paul-Boncour. He is succeeded on October 26 by Albert Sarraut and on November 26 by Camille Chautemps. February * February 1 – Adolf Hitler gives his "Proclamation to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2018 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
