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Backcross
Backcrossing is a crossing of a hybrid with one of its parents or an individual genetically similar to its parent, to achieve offspring with a genetic identity closer to that of the parent. It is used in horticulture, animal breeding, and production of gene knockout organisms. Backcrossed hybrids are sometimes described with acronym "BC"; for example, an F1 hybrid crossed with one of its parents (or a genetically similar individual) can be termed a BC1 hybrid, and a further cross of the BC1 hybrid to the same parent (or a genetically similar individual) produces a BC2 hybrid. Plants Advantages * If the recurrent parent is an elite genotype, at the end of the backcrossing programme, an elite genotype is recovered. * As no "new" recombination results, the elite combination is not lost. Disadvantages * It works poorly for quantitative traits. * It is more restricted for recessive traits. * In practice, sections of genome from the nonrecurrent parents are often still present and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Backcrossing Mice From Chimera
Backcrossing is a crossing of a Hybrid (biology), hybrid with one of its parents or an individual genetically similar to its parent, to achieve offspring with a genetic identity closer to that of the parent. It is used in horticulture, animal breeding, and production of gene knockout organisms. Backcrossed hybrids are sometimes described with acronym "BC"; for example, an F1 hybrid crossed with one of its parents (or a genetically similar individual) can be termed a BC1 hybrid, and a further cross of the BC1 hybrid to the same parent (or a genetically similar individual) produces a BC2 hybrid. Plants Advantages * If the recurrent parent is an elite genotype, at the end of the backcrossing programme, an elite genotype is recovered. * As no "new" Genetic recombination, recombination results, the elite combination is not lost. Disadvantages * It works poorly for quantitative traits. * It is more restricted for recessive traits. * In practice, sections of genome from the nonrecurre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hybrid (biology)
In biology, a hybrid is the offspring resulting from combining the qualities of two organisms of different varieties, subspecies, species or genera through sexual reproduction. Generally, it means that each cell has genetic material from two different organisms, whereas an individual where some cells are derived from a different organism is called a chimera. Hybrids are not always intermediates between their parents such as in blending inheritance (a now discredited theory in modern genetics by particulate inheritance), but can show hybrid vigor, sometimes growing larger or taller than either parent. The concept of a hybrid is interpreted differently in animal and plant breeding, where there is interest in the individual parentage. In genetics, attention is focused on the numbers of chromosomes. In taxonomy, a key question is how closely related the parent species are. Species are reproductively isolated by strong barriers to hybridization, which include genetic and morph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Introgression Line
Introgression, also known as introgressive hybridization, in genetics is the transfer of genetic material from one species into the gene pool of another by the repeated backcrossing of an interspecific hybrid with one of its parent species. Introgression is a long-term process, even when artificial; it may take many hybrid generations before significant backcrossing occurs. This process is distinct from most forms of gene flow in that it occurs between two populations of different species, rather than two populations of the same species. Introgression also differs from simple hybridization. Simple hybridization results in a relatively even mixture; gene and allele frequencies in the first generation will be a uniform mix of two parental species, such as that observed in mules. Introgression, on the other hand, results in a complex, highly variable mixture of genes, and may only involve a minimal percentage of the donor genome. Definition Introgression or introgressive hybridizat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Population
Population is a set of humans or other organisms in a given region or area. Governments conduct a census to quantify the resident population size within a given jurisdiction. The term is also applied to non-human animals, microorganisms, and plants, and has specific uses within such fields as ecology and genetics. Etymology The word ''population'' is derived from the Late Latin ''populatio'' (a people, a multitude), which itself is derived from the Latin word ''populus'' (a people). Use of the term Social sciences In sociology and population geography, population refers to a group of human beings with some predefined feature in common, such as location, Race (human categorization), race, ethnicity, nationality, or religion. Ecology In ecology, a population is a group of organisms of the same species which inhabit the same geographical area and are capable of Sexual reproduction, interbreeding. The area of a sexual population is the area where interbreeding is possi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quantitative Trait
Complex traits are phenotypes that are controlled by two or more genes and do not follow Mendelian inheritance, Mendel's Law of Dominance. They may have a range of Gene expression, expression which is typically continuous. Both environmental and genetic factors often impact the variation in expression. Human height is a continuous trait meaning that there is a wide range of heights. There are an estimated 50 genes that affect the height of a human. Environmental factors, like nutrition, also play a role in a human's height. Other examples of complex traits include: crop yield, plant color, and many diseases including diabetes and Parkinson's disease. One major goal of genetic research today is to better understand the molecular mechanisms through which genetic variants act to influence complex traits. Complex traits are also known as polygenic traits and Multigenic trait, multigenic traits. The existence of complex traits, which are far more common than Mendelian traits, represent ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Senecio Eboracensis
''Senecio eboracensis'', the York groundsel or York radiate groundsel, is a flowering plant in the daisy family Asteraceae. It is a hybrid between a native and a non-native introduced species, which naturalised in England but the population failed to sustain itself. It was brought back by captive cultivation. It is a self-pollinating hybrid species of ragwort and one of only six new plant species to be discovered in either the United Kingdom or North America in the last 100 years. The plant was first discovered in York, England in 1979 and last seen in the wild in 1991. A survey by UK government advisory body Natural England found it was driven to extinction by 2000, partly due to the use of weedkiller. Seeds of the plant were stored at the Millennium Seed Bank, successfully germinated, and reintroduced to York in 2023. Description York radiate groundsel is an annual herbaceous plant that sets its seed within the 3 months that it takes this plant to mature from germination to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Culture
Cell culture or tissue culture is the process by which cell (biology), cells are grown under controlled conditions, generally outside of their natural environment. After cells of interest have been Cell isolation, isolated from living tissue, they can subsequently be maintained under carefully controlled conditions. They need to be kept at body temperature (37 °C) in an incubator. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or rich growth medium, medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases (Carbon dioxide, CO2, Oxygen, O2), and regulates the physio-chemical environment (Buffer solution, pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown free floating in a medium as a suspension culture. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Marker
In molecular biology and other fields, a molecular marker is a molecule, sampled from some source, that gives information about its source. For example, DNA is a molecular marker that gives information about the organism from which it was taken. For another example, some proteins can be molecular markers of Alzheimer's disease in a person from which they are taken. Molecular markers may be non-biological. Non-biological markers are often used in environmental studies. Genetic markers In genetics, a molecular marker (identified as genetic marker) is a fragment of DNA that is associated with a certain location within the genome A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as .... Molecular markers are used in molecular biology and biotechnology to identify a particular sequence ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Positive Selectable Marker
Positive is a property of positivity and may refer to: Mathematics and science * Positive formula, a logical formula not containing negation * Positive number, a number that is greater than 0 * Plus sign, the sign "+" used to indicate a positive number * Positive operator, a type of linear operator in mathematics * Positive result, a result that has been found significant in statistical hypothesis testing * Positive test, a diagnostic test result that indicates some parameter being evaluated was present * Positive charge, one of the two types of electrical charge * Positive (electrical polarity), in electrical circuits * Positive lens, in optics * Positive (photography), a positive image, in which the color and luminance correlates directly with that in the depicted scene * Positive sense, said of an RNA sequence that codes for a protein Philosophy and humanities * Affirmative (policy debate), the team which affirms the resolution * Negative and positive rights, conce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stem Cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50 to 150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. '' In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, whe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Selection (biology)
Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the Heredity, heritable traits characteristic of a population over generations. Charles Darwin popularised the term "natural selection", contrasting it with selective breeding, artificial selection, which is intentional, whereas natural selection is not. Genetic diversity, Variation of traits, both Genotype, genotypic and phenotypic, exists within all populations of organisms. However, some traits are more likely to facilitate survival and reproductive success. Thus, these traits are passed the next generation. These traits can also become more Allele frequency, common within a population if the environment that favours these traits remains fixed. If new traits become more favoured due to changes in a specific Ecological niche, niche, microevolution occurs. If new traits become more favoured due to changes in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
