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Anduril (workflow Engine)
Anduril is an open source component-based workflow framework for scientific data analysis developed at the Systems Biology Laboratory, University of Helsinki. Anduril is designed to enable systematic, flexible and efficient data analysis, particularly in the field of high-throughput experiments in biomedical research. The workflow system currently provides components for several types of analysis such as sequencing, gene expression, SNP, ChIP-on-chip, comparative genomic hybridization and exon microarray analysis as well as cytometry and cell imaging analysis. Architecture and features A workflow is a series of processing steps connected together so that the output of one step is used as the input of another. Processing steps implement data analysis tasks such as data importing, statistical tests and report generation. In Anduril, processing steps are implemented using components, which are reusable executable code that can be written in any programming language. Components ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anduril Workflow Engine Logo V , a defense technology company co-founded in 2017 by entrepreneur Palmer Luckey
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Anduril may refer to: * Andúril, a fictional sword in J. R. R. Tolkien's Middle-earth fantasy writings, originally known as Narsil * Anduril (workflow engine), an open-source workflow framework * Anduril Industries Palmer Freeman Luckey (born September 19, 1992) is an American entrepreneur best known as the founder of Oculus VR and designer of the Oculus Rift, a virtual reality head-mounted display that is widely credited with reviving the virtual reality ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lua (programming Language)
Lua ( ; from meaning '' moon'') is a lightweight, high-level, multi-paradigm programming language designed primarily for embedded use in applications. Lua is cross-platform, since the interpreter of compiled bytecode is written in ANSI C, and Lua has a relatively simple C API to embed it into applications. Lua originated in 1993 as a language for extending software applications to meet the increasing demand for customization at the time. It provided the basic facilities of most procedural programming languages, but more complicated or domain-specific features were not included; rather, it included mechanisms for extending the language, allowing programmers to implement such features. As Lua was intended to be a general embeddable extension language, the designers of Lua focused on improving its speed, portability, extensibility, and ease-of-use in development. History Lua was created in 1993 by Roberto Ierusalimschy, Luiz Henrique de Figueiredo, and Waldemar Celes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kepler Scientific Workflow System
Kepler is a free software system for designing, executing, reusing, evolving, archiving, and sharing scientific workflows.Ludäscher B., Altintas I., Berkley C., Higgins D., Jaeger-Frank E., Jones M., Lee E., Tao J., Zhao Y. 2006. Scientific Workflow Management and the Kepler System. Special Issue: Workflow in Grid Systems. Concurrency and Computation: Practice & Experience 18(10): 1039-1065.Altintas I, Berkley C, Jaeger E, Jones M, Ludäscher B, Mock S. 2004. Kepler: An Extensible System for Design and Execution of Scientific Workflows. Proceedings of the Future of Grid Data Environments, Global Grid Forum 10.Michener, William K., James H. Beach, Matthew B. Jones, Bertram Ludaescher, Deana D. Pennington, Ricardo S. Pereira, Arcot Rajasekar, and Mark Schildhauer. 2007. "A Knowledge Environment for the Biodiversity and Ecological Sciences", Journal of Intelligent Information Systems, 29(1): 111-126. Kepler's facilities provide process and data monitoring, provenance information, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GenePattern
GenePattern is a freely available computational biology open-source software package originally created and developed at the Broad Institute for the analysis of genomic data. Designed to enable researchers to develop, capture, and reproduce genomic analysis methodologies, GenePattern was first released in 2004. GenePattern is currently developed at the University of California, San Diego. Functionality GenePattern is a powerful scientific workflow system that provides access to hundreds of genomic analysis tools. Use these analysis tools as building blocks to design sophisticated analysis pipelines that capture the methods, parameters, and data used to produce analysis results. Pipelines can be used to create, edit and share reproducible in silico results. Project Objectives # Accessibility: Run over 200 regularly updated analysis and visualization tools (that support data preprocessing, gene expression analysis, proteomics, Single nucleotide polymorphism (SNP) analysis, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics Workflow Management Systems
A bioinformatics workflow management system is a specialized form of workflow management system designed specifically to compose and execute a series of computational or data manipulation steps, or a workflow, that relate to bioinformatics. There are currently many different workflow systems. Some have been developed more generally as scientific workflow systems for use by scientists from many different disciplines like astronomy and earth science. All such systems are based on an abstract representation of how a computation proceeds in the form of a directed graph, where each node represents a task to be executed and edges represent either data flow or execution dependencies between different tasks. Each system typically provides a visual front-end, allowing the user to build and modify complex applications with little or no programming expertise. Examples In alphabetical order, some examples of bioinformatics workflow management systems include: * Anduril bioinformatics and i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ingenuity Systems
QIAGEN Silicon Valley (formerly known as Ingenuity Systems, Inc) is a company based in Redwood City, California, USA, to analyze complex biological systems. QIAGEN Silicon Valley's first product, IPA, was introduced in 2003, and is used to help researchers analyze omics data and model biological systems. The software has been cited in thousands of scientific molecular biology publications and is one of several tools for systems biology researchers and bioinformaticians in drug discovery and institutional research. Technology All QIAGEN Silicon Valley use the Ingenuity Knowledge Base, which contains biological and chemical interactions and functional annotations created from millions of individually modeled relationships between proteins, genes, complexes, cells, tissues, drugs, and diseases. Each relationship originates from reported experimental facts from primary literature sources, including peer-reviewed journal articles and textbooks. The knowledge acquisition and extract ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Time Series
In mathematics, a time series is a series of data points indexed (or listed or graphed) in time order. Most commonly, a time series is a sequence taken at successive equally spaced points in time. Thus it is a sequence of discrete-time data. Examples of time series are heights of ocean tides, counts of sunspots, and the daily closing value of the Dow Jones Industrial Average. A time series is very frequently plotted via a run chart (which is a temporal line chart). Time series are used in statistics, signal processing, pattern recognition, econometrics, mathematical finance, weather forecasting, earthquake prediction, electroencephalography, control engineering, astronomy, communications engineering, and largely in any domain of applied science and engineering which involves temporal measurements. Time series ''analysis'' comprises methods for analyzing time series data in order to extract meaningful statistics and other characteristics of the data. Time series ''fore ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carcinogenesis
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division. Cell division is a physiological process that occurs in almost all tissues and under a variety of circumstances. Normally, the balance between proliferation and programmed cell death, in the form of apoptosis, is maintained to ensure the integrity of tissues and organs. According to the prevailing accepted theory of carcinogenesis, the somatic mutation theory, mutations in DNA and epimutations that lead to cancer disrupt these orderly processes by interfering with the programming regulating the processes, upsetting the normal balance between proliferation and cell death. This results in uncontrolled cell division and the evolution of those cells by natural selection in the body. Only certain mutations lead to canc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer Research
Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery, radiation therapy, chemotherapy, hormone therapy, immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards therapies derived from biotechnology research, such as cancer immunotherapy and gene therapy. Cancer research is done in academia, research institutes, and corporate environments, and is largely government funded. History Cancer research has been ongoing for centuries. Early research focused on the causes of cancer. Percivall Pott identified the first environmental trigger (chimney soot) for cancer in 1775 and cigarette smoking was identi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Data Integration
Data integration involves combining data residing in different sources and providing users with a unified view of them. This process becomes significant in a variety of situations, which include both commercial (such as when two similar companies need to merge their databases) and scientific (combining research results from different bioinformatics repositories, for example) domains. Data integration appears with increasing frequency as the volume (that is, big data) and the need to share existing data explodes. It has become the focus of extensive theoretical work, and numerous open problems remain unsolved. Data integration encourages collaboration between internal as well as external users. The data being integrated must be received from a heterogeneous database system and transformed to a single coherent data store that provides synchronous data across a network of files for clients. A common use of data integration is in data mining when analyzing and extracting informati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
