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Al Hakum (Iraq)
Al Hakum — also spelled Al Hakam — was at one time Iraq's most sophisticated and largest biological weapons (BW) production factory. The facility was part of a large military complex at Jurf Al Sakhar (Jur al-Sahkar), about 60-70 kilometers southwest of Baghdad, near al-Musayyib. It produced large quantities of botulinum toxin and anthrax from 1989 to 1996. The name derives from the common Arabic language, Arabic name or title Hakam (title), Al Hakam ("The Judge"), one of the Names of God in the Qur'an. History In the early 1980s, Iraq (under Saddam Hussein) violated the Biological Weapons Convention (BWC) by establishing extensive programs for the development of both chemical and biological weapons. Detailed confirmation of these programs only surfaced in the wake of the Gulf War (1990–91), following investigations conducted by the United Nations Special Commission (UNSCOM) in charge of the disarmament of Saddam's Iraq. One of several BW facilities in Iraq, the "Single-Cell P ...
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Iraq
Iraq,; ku, عێراق, translit=Êraq officially the Republic of Iraq, '; ku, کۆماری عێراق, translit=Komarî Êraq is a country in Western Asia. It is bordered by Turkey to Iraq–Turkey border, the north, Iran to Iran–Iraq border, the east, the Persian Gulf and Kuwait to the southeast, Saudi Arabia to the south, Jordan to Iraq–Jordan border, the southwest and Syria to Iraq–Syria border, the west. The Capital city, capital and largest city is Baghdad. Iraq is home to diverse ethnic groups including Iraqi Arabs, Kurds, Iraqi Turkmen, Turkmens, Assyrian people, Assyrians, Armenians in Iraq, Armenians, Yazidis, Mandaeans, Iranians in Iraq, Persians and Shabaks, Shabakis with similarly diverse Geography of Iraq, geography and Wildlife of Iraq, wildlife. The vast majority of the country's 44 million residents are Muslims – the notable other faiths are Christianity in Iraq, Christianity, Yazidism, Mandaeism, Yarsanism and Zoroastrianism. The official langu ...
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Bacillus Anthracis
''Bacillus anthracis'' is a gram-positive and rod-shaped bacterium that causes anthrax, a deadly disease to livestock and, occasionally, to humans. It is the only permanent (obligate) pathogen within the genus '' Bacillus''. Its infection is a type of zoonosis, as it is transmitted from animals to humans. It was discovered by a German physician Robert Koch in 1876, and became the first bacterium to be experimentally shown as a pathogen. The discovery was also the first scientific evidence for the germ theory of diseases. ''B. anthracis'' measures about 3 to 5 μm long and 1 to 1.2 μm wide. The reference genome consists of a 5,227,419 bp circular chromosome and two extrachromosomal DNA plasmids, pXO1 and pXO2, of 181,677 and 94,830 bp respectively, which are responsible for the pathogenicity. It forms a protective layer called endospore by which it can remain inactive for many years and suddenly becomes infective under suitable environmental conditions. Because of the resil ...
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Iraqi Biological Weapons Program
Saddam Hussein (1937–2006) began an extensive biological weapons (BW) program in Iraq in the early 1980s, despite having signed (but not ratified until 1991) the Biological Weapons Convention (BWC) of 1972. Details of the BW program and a chemical weapons program surfaced after the Gulf War (1990–91) during the disarmament of Iraq under the United Nations Special Commission (UNSCOM). By the end of the war, program scientists had investigated the BW potential of five bacterial strains, one fungal strain, five types of virus, and four toxins. Of these, three—anthrax, botulinum and aflatoxin—had proceeded to weaponization for deployment. Because of the UN disarmament program that followed the war, more is known today about the once-secret bioweapons program in Iraq than that of any other nation. The program no longer existed when the George W. Bush administration cited it as justification for its 2003 invasion of Iraq and the subsequent Iraq War. The program Startup and ...
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2003 Invasion Of Iraq
The 2003 invasion of Iraq was a United States-led invasion of the Republic of Iraq and the first stage of the Iraq War. The invasion phase began on 19 March 2003 (air) and 20 March 2003 (ground) and lasted just over one month, including 26 days of major combat operations, in which a combined force of troops from the United States, the United Kingdom, Australia, and Poland invaded Iraq. Twenty-two days after the first day of the invasion, the capital city of Baghdad was captured by Coalition forces on 9 April 2003 after the six-day-long Battle of Baghdad. This early stage of the war formally ended on 1 May 2003 when U.S. President George W. Bush declared the "end of major combat operations" in his Mission Accomplished speech, after which the Coalition Provisional Authority (CPA) was established as the first of several successive transitional governments leading up to the first Iraqi parliamentary election in January 2005. U.S. military forces later remained in Iraq ...
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The Demon In The Freezer
''The Demon in the Freezer'' is a 2002 nonfiction book on the biological weapon agents smallpox and anthrax and how the American government develops defensive measures against them. It was written by journalist Richard Preston, also author of the best-selling book ''The Hot Zone'' (1994), about ebolavirus outbreaks in Africa and Reston, Virginia and the U.S. government's response to them. The book is primarily an account of the Smallpox Eradication Program (1967–1980), the ongoing perception by the U.S. government that smallpox is still a potential bioterrorism agent, and the controversy over whether or not the remaining samples of smallpox virus in Atlanta and Moscow (the "demon" in the freezer) should be finally destroyed. However, the writer was overtaken by events—the 9/11 attacks and the anthrax letter incidents (called "Amerithrax"), both in 2001—and so much of the book interweaves the anthrax investigation with the smallpox material in a manner some critics have ...
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Richard Preston
Richard Preston (born August 5, 1954) is a writer for ''The New Yorker'' and bestselling author who has written books about infectious disease, bioterrorism, redwoods and other subjects, as well as fiction. Biography Preston was born in Cambridge, Massachusetts. He graduated Wellesley High School in Massachusetts in 1972 and attended Pomona College in Claremont, California. He earned a Ph.D. in English from Princeton University in 1983. His 1992 ''New Yorker'' article "Crisis in the Hot Zone" was expanded into his breakout book, ''The Hot Zone'' (1994). It is classified as a "non-fiction thriller" about ebolaviruses. He learned of ebola through such contacts as U.S. Army researchers Drs. C.J. Peters and Nancy Jaax. His fascination began during a visit to Africa where he was an eyewitness to epidemics. The book served as the (very loose) basis of the Hollywood movie ''Outbreak'' (1995) about military machinations surrounding a fictional "Motaba virus". Preston's novel ''The ...
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Bacillus Thuringiensis
''Bacillus thuringiensis'' (or Bt) is a gram-positive, soil-dwelling bacterium, the most commonly used biological pesticide worldwide. ''B. thuringiensis'' also occurs naturally in the gut of caterpillars of various types of moths and butterflies, as well on leaf surfaces, aquatic environments, animal feces, insect-rich environments, and flour mills and grain-storage facilities. It has also been observed to parasitize other moths such as '' Cadra calidella''—in laboratory experiments working with ''C. calidella'', many of the moths were diseased due to this parasite. During sporulation, many Bt strains produce crystal proteins (proteinaceous inclusions), called delta endotoxins, that have insecticidal action. This has led to their use as insecticides, and more recently to genetically modified crops using Bt genes, such as Bt corn. Many crystal-producing Bt strains, though, do not have insecticidal properties. The subspecies ''israelensis'' is commonly used for control ...
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Aflatoxin
Aflatoxins are various poisonous carcinogens and mutagens that are produced by certain molds, particularly '' Aspergillus'' species. The fungi grow in soil, decaying vegetation and various staple foodstuffs and commodities such as hay, sweetcorn, wheat, millet, sorghum, cassava, rice, chili peppers, cottonseed, peanuts, tree nuts, sesame seeds, sunflower seeds, and various spices. In short, the relevant fungi grow on almost any crop or food. When such contaminated food is processed or consumed, the aflatoxins enter the general food supply. They have been found in both pet and human foods, as well as in feedstocks for agricultural animals. Animals fed contaminated food can pass aflatoxin transformation products into eggs, milk products, and meat. For example, contaminated poultry feed is the suspected source of aflatoxin-contaminated chicken meat and eggs in Pakistan. Children are particularly affected by aflatoxin exposure, which is associated with stunted growth, delaye ...
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Ricin
Ricin ( ) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, ''Ricinus communis''. The median lethal dose (LD50) of ricin for mice is around 22 micrograms per kilogram of body weight via intraperitoneal injection. Oral exposure to ricin is far less toxic. An estimated lethal oral dose in humans is approximately 1 milligram per kilogram of body weight. Ricin was first described by Peter Hermann Stillmark, the founder of lectinology. Biochemistry Ricin is classified as a type 2 ribosome-inactivating protein (RIP). Whereas type 1 RIPs are composed of a single protein chain that possesses catalytic activity, type 2 RIPs, also known as holotoxins, are composed of two different protein chains that form a heterodimeric complex. Type 2 RIPs consist of an A chain that is functionally equivalent to a type 1 RIP, covalently connected by a single disulfide bond to a B chain that is catalytically inactive, but serve ...
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Camel Pox
A camel (from: la, camelus and grc-gre, κάμηλος (''kamēlos'') from Hebrew or Phoenician: גָמָל ''gāmāl''.) is an even-toed ungulate in the genus ''Camelus'' that bears distinctive fatty deposits known as "humps" on its back. Camels have long been domesticated and, as livestock, they provide food (milk and meat) and textiles (fiber and felt from hair). Camels are working animals especially suited to their desert habitat and are a vital means of transport for passengers and cargo. There are three surviving species of camel. The one-humped dromedary makes up 94% of the world's camel population, and the two-humped Bactrian camel makes up 6%. The Wild Bactrian camel is a separate species and is now critically endangered. The word ''camel'' is also used informally in a wider sense, where the more correct term is "camelid", to include all seven species of the family Camelidae: the true camels (the above three species), along with the "New World" camelids: the llama, ...
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Rotavirus
''Rotavirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae''. Rotaviruses are the most common cause of diarrhoeal disease among infants and young children. Nearly every child in the world is infected with a rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe. Adults are rarely affected. There are nine species of the genus, referred to as A, B, C, D, F, G, H, I and J. ''Rotavirus A'', the most common species, causes more than 90% of rotavirus infections in humans. The virus is transmitted by the faecal-oral route. It infects and damages the cells that line the small intestine and causes gastroenteritis (which is often called "stomach flu" despite having no relation to influenza). Although rotavirus was discovered in 1973 by Ruth Bishop and her colleagues by electron micrograph images and accounts for approximately one third of hospitalisations for severe diarrhoea in infants a ...
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Conjunctivitis
Conjunctivitis, also known as pink eye, is inflammation of the outermost layer of the white part of the eye and the inner surface of the eyelid. It makes the eye appear pink or reddish. Pain, burning, scratchiness, or itchiness may occur. The affected eye may have increased tears or be "stuck shut" in the morning. Swelling of the white part of the eye may also occur. Itching is more common in cases due to allergies. Conjunctivitis can affect one or both eyes. The most common infectious causes are viral followed by bacterial. The viral infection may occur along with other symptoms of a common cold. Both viral and bacterial cases are easily spread between people. Allergies to pollen or animal hair are also a common cause. Diagnosis is often based on signs and symptoms. Occasionally, a sample of the discharge is sent for culture. Prevention is partly by handwashing. Treatment depends on the underlying cause. In the majority of viral cases, there is no specific treatment. Mo ...
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