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ATC Code A03
A03A Drugs for functional gastrointestinal disorders A03AA Chemical synthesis, Synthetic anticholinergics, esters with Tertiary amine, tertiary amino group :A03AA01 Oxyphencyclimine :A03AA03 Camylofin :A03AA04 Mebeverine :A03AA05 Trimebutine :A03AA06 Rociverine :A03AA07 Dicycloverine :A03AA08 Dihexyverine :A03AA09 Difemerine :A03AA30 Piperidolate A03AB Synthetic anticholinergics, quaternary ammonium compounds :A03AB01 Benzilone :A03AB02 Glycopyrronium bromide :A03AB03 Oxyphenonium :A03AB04 Penthienate :A03AB05 Propantheline :A03AB06 Otilonium bromide :A03AB07 Methantheline :A03AB08 Tridihexethyl :A03AB09 Isopropamide :A03AB10 Hexocyclium :A03AB11 Poldine :A03AB12 Mepenzolate :A03AB13 Bevonium :A03AB14 Pipenzolate :A03AB15 Diphemanil :A03AB16 (2-benzhydryloxyethyl)diethyl-methylammonium iodide :A03AB17 Tiemonium iodide :A03AB18 Prifinium bromide :A03AB19 Timepidium bromide :A03AB21 Fenpiverinium :A03AB53 Oxyphenonium, combinations :QA03AB90 Benzetimide :QA03AB92 Carbachol :QA03AB9 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Functional Gastrointestinal Disorder
Functional gastrointestinal disorders (FGID), also known as disorders of gut–brain interaction, include a number of separate idiopathic disorders which affect different parts of the human gastrointestinal tract, gastrointestinal tract and involve visceral hypersensitivity and Gastrointestinal physiology#Motility, motility disturbances. Definition Using the Delphi method, the Rome process, Rome Foundation and its board of directors, chairs and co-chairs of the Rome process, ROME IV committees developed the current definition for disorders of gut-brain interaction. A group of disorders classified by GI symptoms related to any combination of: * Motility disturbance * Visceral hypersensitivity * Altered mucosal and immune function * Altered gut microbiota * Altered central nervous system (CNS) processing Classification Terms such as ''functional colonic disease'' (or ''functional bowel disorder'') refer in medicine to a group of bowel disorders which are characterized by chronic ab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Penthienate
Penthienate is an anticholinergic and has actions similar to atropine. It reduces gastric motility and secretion and is used for the treatment of peptic ulcer and dyspepsia Indigestion, also known as dyspepsia or upset stomach, is a condition of impaired digestion. Symptoms may include upper abdominal fullness, heartburn, nausea, belching, or upper abdominal pain. People may also experience feeling full earlier .... References Muscarinic antagonists Thiophenes Tertiary alcohols Quaternary ammonium compounds Carboxylate esters Cyclopentyl compounds {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prifinium Bromide
Prifinium bromide is a pharmaceutical drug used primarily in the treatment of irritable bowel syndrome due to its action as an anticholinergic. Prifinium bromide's mechanism of action is believed to be due to its activity as an antispasmodic agent. Prifinium bromide is an antimuscarinic A muscarinic acetylcholine receptor antagonist, also simply known as a muscarinic antagonist or as an antimuscarinic agent, is a type of anticholinergic drug that blocks the activity of the muscarinic acetylcholine receptors (mAChRs). The muscarin .... References Muscarinic antagonists Quaternary ammonium compounds Pyrrolidines Alkene derivatives {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tiemonium Iodide
Tiemonium iodide is an antimuscarinic. It is poorly absorbed from the gut. The active moiety is tiemonium, a quaternary ammonium cation In organic chemistry, quaternary ammonium cations, also known as quats, are positively-charged polyatomic ions of the structure , where R is an alkyl group, an aryl group or organyl group. Unlike the ammonium ion () and the primary, secondary, .... References Iodides M1 receptor antagonists M2 receptor antagonists M3 receptor antagonists M4 receptor antagonists M5 receptor antagonists Morpholines Quaternary ammonium compounds Tertiary alcohols Thiophenes {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diphemanil
In the field of pharmacology, diphemanil metilsulfate also known as diphemanil methylsulfate is an antimuscarinic (an agent that blocks the action of the natural neurotransmitter A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a Chemical synapse, synapse. The cell receiving the signal, or target cell, may be another neuron, but could also be a gland or muscle cell. Neurotra ... acetylcholine). References Muscarinic antagonists Quaternary ammonium compounds Piperidines {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pipenzolate
Pipenzolate bromide is a pharmaceutical drug that has been studied as an antispasmodic agent and to treat peptic ulcer. Mechanism of action Pipenzolate bromide acts as an antimuscarinic agent. It binds to muscarinic acetylcholine receptors as an antagonist therefore preventing acetylcholine Acetylcholine (ACh) is an organic compound that functions in the brain and body of many types of animals (including humans) as a neurotransmitter. Its name is derived from its chemical structure: it is an ester of acetic acid and choline. Par ... from binding to the receptors. References Muscarinic antagonists Quaternary ammonium compounds Piperidines Tertiary alcohols {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bevonium
Bevonium (piribenzil) is an antimuscarinic with antispasmodic An antispasmodic (synonym: spasmolytic) is a pharmaceutical drug or other agent that suppresses muscle spasms. Smooth muscle spasm One type of antispasmodics is used for smooth muscle relaxation, especially in tubular organs of the gastrointestina ... and bronchodilating properties. The compound is commonly used as the methyl sulfate (metilsulfate). References Muscarinic antagonists Quaternary ammonium compounds Piperidines Tertiary alcohols {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mepenzolate
Mepenzolate is an antimuscarinic A muscarinic acetylcholine receptor antagonist, also simply known as a muscarinic antagonist or as an antimuscarinic agent, is a type of anticholinergic drug that blocks the activity of the muscarinic acetylcholine receptors (mAChRs). The muscarin ... medication primarily used to treat peptic ulcers by reducing stomach acid secretion. It is the methylated version of N-Methyl-3-piperidyl benzilate. Pharmacology Mepenzolate works by blocking the action of acetylcholine on muscarinic receptors in the gastrointestinal tract. This action reduces the secretion of stomach acid and slows intestinal motility, making it useful in the management of peptic ulcers and other gastrointestinal disorders. Chemical Structure The chemical structure of Mepenzolate is characterized by the presence of a piperidyl group attached to a benzilate moiety, with an additional methyl group. This structure is similar to that of N-Methyl-3-piperidyl benzilate, but with a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poldine
Poldine is an antimuscarinic that is used to treat peptic ulcer Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer, while ...s. References Muscarinic antagonists Quaternary ammonium compounds Pyrrolidines Tertiary alcohols Carboxylate esters {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hexocyclium
Hexocyclium is an antimuscarinic A muscarinic acetylcholine receptor antagonist, also simply known as a muscarinic antagonist or as an antimuscarinic agent, is a type of anticholinergic drug that blocks the activity of the muscarinic acetylcholine receptors (mAChRs). The muscarin .... It is used in the form of its methyl sulfate, called hexocyclium metilsulfate. References M1 receptor antagonists M3 receptor antagonists M4 receptor antagonists M5 receptor antagonists Phenylethanolamines Piperazines Quaternary ammonium compounds Tertiary alcohols {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isopropamide
Isopropamide (R79) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica Johnson & Johnson Innovative Medicine (formerly Janssen Pharmaceuticals) is a Belgian pharmaceutical company headquartered in Beerse, Belgium, and wholly owned by Johnson & Johnson. It was founded in 1953 by Paul Janssen. In 1961, Janssen Ph ... in 1954. References Further reading * * Muscarinic antagonists Quaternary ammonium compounds Carboxamides Janssen Pharmaceutica Belgian inventions Diisopropylamino compounds {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tridihexethyl
Tridihexethyl (which is commonly used as its chloride salt, tridihexethyl chloride) is an anticholinergic, antimuscarinic and antispasmodic drug. It may be used, usually in combination with other drugs, to treat acquired nystagmus or peptic ulcer Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer, while ... disease. Many patients discontinue the drug because of unwanted side effects. It is also known as Pathilon or Propethonum. References Muscarinic antagonists Quaternary ammonium compounds Tertiary alcohols {{gastrointestinal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
