3,4′-dihydroxystilbene
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3,4′-dihydroxystilbene
3,4′-Dihydroxystilbene is a stilbenoid found in the roots of '' Hydrangea macrophylla''.Lunularic acid and related compounds in liverworts, algae and Hydrangea. John Gorham, Phytochemistry, 1977, Volume 16, Issue 2, Pages 249–253, See also * 4,4'-Dihydroxystilbene * Resveratrol Resveratrol (3,5,4′-trihydroxy-''trans''-stilbene) is a stilbenoid, a type of natural phenol or polyphenol and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacterium, ba ... References Stilbenoids {{aromatic-stub ...
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Hydrangea Macrophylla
''Hydrangea macrophylla'' is a species of flowering plant in the family (biology), family Hydrangeaceae, native plant, native and endemism, endemic to Japan. It is a deciduous shrub growing to tall by or more broad with large heads of pink or blue flowers in summer and autumn. It is currently treated as monotypic, with no subspecies or varieties. Common names include bigleaf hydrangea, and, for particular cultivar groups, the names lacecap hydrangea, mophead hydrangea, and hortensia. It is widely cultivated in many parts of the world in many climates. It is not to be confused with ''Hydrangea aspera, H. aspera'' 'Macrophylla'. Distribution and habitat ''Hydrangea macrophylla'' is endemic to Japan, where it occurs in coastal habitats from Honshu southwards. Natural wild plants, formerly sometimes distinguished as ''H. macrophylla'' var. ''normalis'' E.H.Wilson, have "lacecap" structure flowerheads, with a few large sterile showy bract-like flowers that act as targets for polli ...
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Stilbenoid
Stilbenoids are hydroxylated derivatives of stilbene. They have a C6–C2–C6 structure. In biochemical terms, they belong to the family of phenylpropanoids and share most of their biosynthesis pathway with Chalconoid, chalcones. Most stilbenoids are produced by plants, and the only known exception is the antimicrobial stilbenoid drug tapinarof which is biosynthesized by the Gram-negative bacterium ''Photorhabdus luminescens.'' Chemistry Stilbenoids are hydroxylated derivatives of stilbene and have a C6–C2–C6 structure. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with Chalconoid, chalcones. Under UV irradiation, stilbene and its derivatives undergo intramolecular cyclization, called stilbene photocyclization to form dihydrophenanthrenes. Oligomeric forms are known as oligostilbenoids. Types ;Aglycones * Piceatannol in the roots of Norway spruces * Pinosylvin is a fungal toxin protecting wood from fungal infection, found in t ...
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4,4'-Dihydroxystilbene
Stilbestrol, or stilboestrol, also known as 4,4'-dihydroxystilbene or 4,4'-stilbenediol, is a stilbenoid nonsteroidal estrogen and the parent compound of a group of more potent nonsteroidal estrogen derivatives that includes, most notably, diethylstilbestrol (DES). The term "stilbestrol" is often used incorrectly to refer to DES, but they are not the same compound. Stilbestrol itself is an active estrogen but is less potent than DES and other derivatives. Stilbestrol derivatives The stilbestrol estrogenic drugs include the following: * Acefluranol (an antiestrogen) * Benzestrol (''technically'' not a stilbestrol derivative due to its elongated central chain, but a very close analogue and grouped with the stilbestrol estrogens in any case) * Bifluranol * Dienestrol ** Dienestrol acetate * Diethylstilbestrol (commonly, but erroneously shortened to simply “stilbestrol”) ** Diethylstilbestrol diacetate ** Diethylstilbestrol dilaurate ** Diethylstilbestrol dipalmitate ** Die ...
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Resveratrol
Resveratrol (3,5,4′-trihydroxy-''trans''-stilbene) is a stilbenoid, a type of natural phenol or polyphenol and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacterium, bacteria or fungus, fungi. Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries, and peanuts. Although commonly used as a dietary supplement and studied in laboratory models of human diseases, there is no evidence-based medicine, high-quality evidence that resveratrol improves longevity, lifespan or has a substantial effect on any human disease. Research Resveratrol has been studied for its potential therapeutic use, with little evidence of anti-disease effects or health benefits in humans. Cardiovascular disease There is no evidence of benefit from resveratrol in people who already have heart disease. A 2018 meta-analysis found no effect on systolic blood pressure, systolic or diastolic blood pr ...
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