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1,3-Propanedisulfonic Acid
1,3-Propanedisulfonic acid is a sulfonic acid containing two sulfonate units. Its salts are called eprodisates and have been evaluated as a protector of renal function in AA amyloidosis. See also *Methanedisulfonic acid *Ethanedisulfonic acid Ethanedisulfonic acid is a diprotic sulfonic acid, with pKa values of -1.46 and -2.06, making it a very strong acid. When used in pharmaceutical formulations, the salts with the active ingredient are known as edisylates. See also *Methanedisul ... References Sulfonic acids {{Organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulfonic Acid
In organic chemistry, sulfonic acid (or sulphonic acid) refers to a member of the class of organosulfur compounds with the general formula , where R is an organic alkyl or aryl group and the group a sulfonyl hydroxide. As a substituent, it is known as a sulfo group. A sulfonic acid can be thought of as sulfuric acid with one hydroxyl group replaced by an organic substituent. The parent compound (with the organic substituent replaced by hydrogen) is the parent sulfonic acid, , a tautomer of sulfurous acid, . Salt (chemistry), Salts or esters of sulfonic acids are called sulfonates. Preparation Aryl sulfonic acids are produced by the process of sulfonation. Usually the sulfonating agent is sulfur trioxide. A large scale application of this method is the production of alkylbenzenesulfonic acids: :RC6H5 + SO3 -> RC6H4SO3H In this reaction, sulfur trioxide is an electrophile and the arene is the nucleophile. The reaction is an example of electrophilic aromatic substitution. Alkyl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AA Amyloidosis
AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of various tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose plasma concentration is highest during inflammation. Causes AA amyloidosis is a complication of a number of inflammatory diseases and infections, although only a small portion of patients with these conditions will go on to develop AA amyloidosis. The most common presentation of AA amyloidosis is renal in nature, including proteinuria, nephrotic syndrome and progressive development of chronic kidney disease leading to end stage kidney disease (ESKD) and need for renal replacement therapy (e.g. dialysis or kidney transplantation). A natural history study of AA amyloidosis patients reported a number of conditions associated with AA amyloidosis: * Autoimmune diseases ** ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Journal Of Nephrology And Renovascular Disease
The ''International Journal of Nephrology and Renovascular Disease'' is an open-access peer-reviewed medical journal focusing on kidney and vascular supply studies. It was established in 2008 and is published by Dove Medical Press. It is abstracted and indexed in PubMed, EMBASE, and Scopus Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-l .... External links * English-language journals Open access journals Dove Medical Press academic journals Nephrology journals Publications established in 2008 {{Medical-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methanedisulfonic Acid
Methanedisulfonic acid is the organosulfur compound with the formula CH2(SO3H)2. It is the di sulfonic acid of methane. It is prepared by treatment of methanesulfonic acid with oleum. Its acid strength (pKa) is comparable to that of sulfuric acid.{{Ullmann, doi=10.1002/14356007.a25_503, isbn=3527306730, title=Sulfonic Acids, Aliphatic, year=2000, last1=Kosswig, first1=Kurt See also *Ethanedisulfonic acid *1,3-Propanedisulfonic acid 1,3-Propanedisulfonic acid is a sulfonic acid containing two sulfonate units. Its salts are called eprodisates and have been evaluated as a protector of renal function in AA amyloidosis. See also *Methanedisulfonic acid Methanedisulfonic acid ... References Sulfonic acids ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethanedisulfonic Acid
Ethanedisulfonic acid is a diprotic sulfonic acid, with pKa values of -1.46 and -2.06, making it a very strong acid. When used in pharmaceutical formulations, the salts with the active ingredient are known as edisylates. See also *Methanedisulfonic acid Methanedisulfonic acid is the organosulfur compound with the formula CH2(SO3H)2. It is the di sulfonic acid of methane. It is prepared by treatment of methanesulfonic acid with oleum. Its acid strength (pKa) is comparable to that of sulfuri ... * 1,3-Propanedisulfonic acid References Sulfonic acids {{Organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
