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γ-Butyrolactone
γ-Butyrolactone (GBL) or ''gamma''-butyrolactone is an organic compound with the formula . It is a hygroscopic, colorless, water-miscible liquid with a weak characteristic odor. It is the simplest Γ-lactone, 4-carbon lactone. It is mainly used as an intermediate in the production of other chemicals, such as N-Methyl-2-pyrrolidone, N-methyl-2-pyrrolidone. In humans, GBL acts as a prodrug for Gamma-Hydroxybutyric acid, ''gamma''-hydroxybutyric acid (GHB) and is often used as a Recreational drug use, recreational drug. GHB acts as a central nervous system (CNS) depressant with effects similar to those of barbiturates. Occurrence GBL has been found in extracts from samples of unadulterated wines. This finding indicates that GBL is a naturally occurring component in some wines and may be present in similar products. The concentration detected was approximately 5 μg/mL and was easily observed using a simple extraction technique followed by Gas chromatography-mass spectrometry, GC/M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Depressant
Depressants, also known as central nervous system depressants, or colloquially known as "downers", are drugs that lower neurotransmission levels, decrease the electrical activity of brain cells, or reduce arousal or stimulation in various areas of the brain. Some specific depressants do influence mood, either positively (e.g., opioids) or negatively, but depressants often have no clear impact on mood (e.g., most anticonvulsants). In contrast, stimulants, or "uppers", increase mental alertness, making stimulants the opposite drug class from depressants. Antidepressants are defined by their effect on mood, not on general brain activity, so they form an orthogonal category of drugs. Depressants are closely related to sedatives as a category of drugs, with significant overlap. The terms may sometimes be used interchangeably or may be used in somewhat different contexts. Depressants are widely used throughout the world as prescription medicines and illicit substances. A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
