Topiroxostat
   HOME

TheInfoList



OR:

Topiroxostat (
INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...
; trade names Topiloric, Uriadec) is a drug for the treatment of
gout Gout ( ) is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot and swollen joint, caused by deposition of monosodium urate monohydrate crystals. Pain typically comes on rapidly, reaching maximal intensit ...
and hyperuricemia. It was approved for use in Japan in June 2013. Topiroxostat is a
xanthine oxidase inhibitor A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism. In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhi ...
which reduces serum
urate Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C5H4N4O3. It forms ions and salts known as urates and acid urates, such as ammonium acid urate. Uric acid is a product of the metabolic breakdown o ...
levels.


References

Xanthine oxidase inhibitors Triazoles Pyridines Nitriles {{musculoskeletal-drug-stub