Ralph L. Obendorf
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Ralph Louis Obendorf (born July 11, 1938) is an Emeritus Professor of Crop Physiology at
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to tea ...
who is notable for his research on the health-related components in seeds, particularly fagopyritol A1, which is isosteric to an insulin mediator believed to be deficient in subjects with non-insulin dependent
diabetes mellitus Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ...
(NIDDM or
type II diabetes Type 2 diabetes, formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urinatio ...
) and
polycystic ovary syndrome Polycystic ovary syndrome, or PCOS, is the most common endocrine disorder in women of reproductive age. The syndrome is named after the characteristic cysts which may form on the ovaries, though it is important to note that this is a sign and no ...
, which affects 10% of women of reproductive age.


Career

Obendorf joined the
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to tea ...
faculty as an assistant professor in 1966, became an associate professor in 1971 and a Full Professor in 1978. He became Professor Emeritus in the School of Integrative Plant Science, Section of Soil and Crop Sciences,
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to tea ...
, 2014–present. He was a visiting scientist at the Institute for Cancer Research
Fox Chase Cancer Center Fox Chase Cancer Center is a National Cancer Institute-designated Comprehensive Cancer Center research facility and hospital located in the Fox Chase section of Philadelphia, Pennsylvania, United States. The main facilities of the center are loca ...
in Philadelphia in 1972–73, and 1983 he was a visiting plant physiologist at the Plant Growth Laboratory,
University of California at Davis The University of California, Davis (UC Davis, UCD, or Davis) is a public land-grant research university near Davis, California. Named a Public Ivy, it is the northernmost of the ten campuses of the University of California system. The institut ...
. He was a visiting scientist in Chemical Physiology of Plants, Institut für Pflanzenphysiologie,
University of Vienna The University of Vienna (german: Universität Wien) is a public research university located in Vienna, Austria. It was founded by Duke Rudolph IV in 1365 and is the oldest university in the German-speaking world. With its long and rich hist ...
in 1997. Obendorf was a visiting scholar at the
University of California at San Diego The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public land-grant research university in San Diego, California. Established in 1960 near the pre-existing Scripps Institution of Oceanography, UC San Diego is t ...
in 2004 and 2013–present.


Research

Obendorf's research on the biology of seeds included characterizing the molecular structure and synthesis of galactosyl cyclitols; characterizing the enzymes and genes regulating pathways of soluble carbohydrate biosynthesis and degradation; studying the regulation of embryo growth, maturation, and germination ''in vitro'' and ''in planta''. Obendorf has also done research on somatic embryogenesis, desiccation tolerance, seed water relations; the purification and characterization of pectin methyl esterase. He has studied cell wall polysaccharides and the role of sugars, cyclitols and methanol in seed deterioration and germplasm preservation. His early work characterized imbibitional chilling in soybean, maize and sorghum, stelar lesions and hydrational damage, respiration, energy metabolism and transcription.


Flatulence

Desiccation tolerance in maturing seeds involves the accumulation of non-reducing galactosyl sucrose oligosaccharides such as
stachyose Stachyose is a tetrasaccharide consisting of two α--galactose units, one α--glucose unit, and one β--fructose unit sequentially linked as gal(α1→6)gal(α1→6)glc(α1↔2β)fru. Together with related oligosaccharides such as raffinose, stac ...
and
raffinose Raffinose is a trisaccharide composed of galactose, glucose, and fructose. It can be found in beans, cabbage, brussels sprouts, broccoli, asparagus, other vegetables, and whole grains. Raffinose can be hydrolyzed to D-galactose and sucro ...
. These galactosyl sucrose oligosaccharides cause flatulence in animals and human beings because human beings do not have the enzyme, α-galactosidase to cleave the α-galactosyl linkage. Consequently, the intact galactosyl sucrose oligosaccharide is not absorbed by the digestive tract and the bacteria in the colon use it as a substrate that results in gas formation. As a result of the relationship found between the oligosaccharides and flatulence, the Protein Advisory Group of the
United Nations The United Nations (UN) is an intergovernmental organization whose stated purposes are to maintain international peace and security, develop friendly relations among nations, achieve international cooperation, and be a centre for harmoniz ...
has recommended that the elimination of flatulence associated with the consumption of foods be one of the research priorities. However, Obendorf found that the accumulation of the flatulence-producing oligosaccharides is required for seed germinability and seed desiccation tolerance. Thus the elimination of the flatulence-producing oligosaccharides from seeds would result in a deterioration of the crop that produces them. According to Obendorf,
Breeding seed plants for quality embryos emphasizes elimination of flatulence-producing oligosaccharides. Before this effort proceeds too far, we need to determine if the flatulence-producing maturation sugars are required for desiccation tolerance and storability of seed germplasm, the threshold level required, and if biosynthesis of the
stachyose Stachyose is a tetrasaccharide consisting of two α--galactose units, one α--glucose unit, and one β--fructose unit sequentially linked as gal(α1→6)gal(α1→6)glc(α1↔2β)fru. Together with related oligosaccharides such as raffinose, stac ...
series oligosaccharides and/or oligogalactocyclitols can be regulated genetically and biochemically in parallel with altered desiccation tolerance and storability of seed germplasm.
In 1722,
Jonathan Swift Jonathan Swift (30 November 1667 – 19 October 1745) was an Anglo-Irish satirist, author, essayist, political pamphleteer (first for the Whigs, then for the Tories), poet, and Anglican cleric who became Dean of St Patrick's Cathedral, Dubl ...
wrote a pamphlet entitled, ''The Benefit of Farting Explain'd: or, The fundament-All Cause of the Distempers Incident to the Fair-Sex...''. Recent research indicates that flatulence-producing oligosaccharides may have health benefits for human beings as well as for beans.


Teaching

Obendorf's teaching responsibilities included''Teaching Experience'', ''Undergraduate Research'', ''Independent Research in Biology'', ''Introduction to Research Methods'', ''Field Crop Systems'', and ''Seed Biology'' with an emphasis on training society ready graduates. Obendorf trained more than 230 undergraduates in research, resulting in 52 undergraduate coauthors on refereed journal papers. Obendorf has won numerous teaching awards.


Awards

In 1987, Obendorf won a Medal from Poznan Agriculture University, and a Medal from the Polish Ministry of Agriculture. In 1992, he won a Medal from Warsaw Agricultural University. In 2008 he was presented by Medal by Ryszard J. Górecki, Rector of the University of Warmia and Mazury, Olsztyn, Poland. Obendorf was made an Elected Fellow of the
Crop Science Society of America The Crop Science Society of America (CSSA) is a scientific and professional society of plant biologists and crop scientists based in the United States. About The Crop Science Society of America was founded in 1956 as a daughter society of the ...
in 1995, an Elected Fellow of the
American Society of Agronomy The American Society of Agronomy (ASA) is a scientific and professional society of agronomists and scientists of related disciplines, principally in the United States but with many non-U.S. members as well. About It was founded December 13, 190 ...
in 1996 and an Elected Fellow of the American Association for the Advancement of Science (AAAS) in 2004 and an Elected Fifty-year Life Member in 2016. Obendorf was given an Honorary doctorate at the University of Warmia and Mazury in Olsztyn, Poland in 2002


Personal life

Ralph Obendorf was born on July 11, 1938, in Ripley County, Indiana to Louis Eugene and Miriam Clara (Stegemoller) Obendorf. Obendorf grew up in Indiana. Obendorf married Sharon Kay Randel on March 11, 1967. They have two children: Michael Bradley Obendorf and Kevin Andrew Obendorf.


References


External links


Personal website
Section of Soil and Crop Science, Cornell University
SIPS Section of Soil and Crop Science
Cornell University


Patents held by Ralph L. Obendorf
{{DEFAULTSORT:Obendorf, Ralph L. Plant physiologists Living people 1938 births Cornell University faculty Purdue University alumni University of California, Davis alumni People from Ripley County, Indiana 20th-century American botanists