Pipecuronium (Arduan) is a bisquaternary aminosteroid muscle relaxant which blocks nicotinic acetylcholine receptors at the

neuromuscular junction A neuromuscular junction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber. It allows the motor neuron to transmit a signal to the muscle fiber, causing muscle contraction. Muscles require innervation to ...

. It is also an antagonist of M2 and

M3 muscarinic receptors The muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the human gene CHRM3. The M3 muscarinic receptors are located at many places in t ...

and is the most potent neuromuscular blocking agent of the aminosteroid class. It is sold under the trade names Arduan and Pycuron.

References

Muscle relaxants Quaternary ammonium compounds Piperazines Acetate esters Bromides Nicotinic antagonists Androstanes {{musculoskeletal-drug-stub

See also

References