Pelanserin (TR2515) is an

antagonist An antagonist is a character in a story who is presented as the chief foe of the protagonist. Etymology The English word antagonist comes from the Greek ἀνταγωνιστής – ''antagonistēs'', "opponent, competitor, villain, enemy, riv ...

of the 5-HT₂ and α₁-adrenergic receptors.

Synthesis

The reaction between

isatoic anhydride Isatoic anhydride is an organic compound derived from anthranilic acid. A white solid, it is prepared by reaction of anthranilic acid with phosgene. Reactions Hydrolysis gives carbon dioxide and anthranilic acid. Alcoholysis proceeds similarly, ...

(1) and 1-(3-Aminopropyl)-4-phenylpiperazine 0529-19-5(2) with

phosgene Phosgene is the organic chemical compound with the formula COCl2. It is a toxic, colorless gas; in low concentrations, its musty odor resembles that of freshly cut hay or grass. Phosgene is a valued and important industrial building block, espe ...

completed the synthesis of pelanserin (3).

References

5-HT2 antagonists Alpha-1 blockers {{pharma-stub

Synthesis

See also

References