cGMP-dependent protein kinase 1, alpha isozyme is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that in humans is encoded by the ''PRKG1''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Interactions
PRKG1 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with:
*
GTF2I
General transcription factor II-I is a protein that in humans is encoded by the ''GTF2I'' gene.
Function
This gene encodes a multifunctional phosphoprotein, TFII-I, with roles in transcription and signal transduction. Haploinsuffiency (deletio ...
,
*
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1 is a protein that in humans is encoded by the ''ITPR1'' gene.
Interactions
ITPR1 has been shown to interact with:
* AHCYL1,
* CA8,
* EPB41L1
* FKBP1A,
* MRVI1,
* PRKG1,
* RHOA, and
* TRPC4 ...
,
*
MRVI1
Protein MRVI1 is a protein that in humans is encoded by the ''MRVI1'' gene.
Function
This gene is similar to a mouse putative tumor suppressor gene that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is fo ...
,
RGS2
Regulator of G-protein signaling 2 is a protein that in humans is encoded by the ''RGS2'' gene. It is part of a larger family of RGS proteins that control signalling through G-protein coupled receptors (GPCR).
Function
RGS2 is thought to have p ...
,TNNT1
Slow skeletal muscle troponin T (sTnT) is a protein that in humans is encoded by the ''TNNT1'' gene.
The TNNT1 gene is located at 19q13.4 in the human chromosomal genome, encoding the slow twitch skeletal muscle isoform of troponin T (ssTnT). ss ...
.
References
Further reading
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EC 2.7.11
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