O-2545 is an
analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It ...
cannabinoid
Cannabinoids () are several structural classes of compounds found in the cannabis plant primarily and most animal organisms (although insects lack such receptors) or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tet ...
derivative created by
Organix Inc
Organix Inc is a US fine chemicals company specialising in chemical synthesis of analytical standards and custom synthesis of finished compounds and intermediates.{{Citation needed, date=February 2020
Chemistry
Organix carries out research and de ...
. for use in scientific research. Unlike most cannabinoids discovered to date, it is water-soluble, which gives it considerable advantages over many related cannabinoids. It has high affinity for both
CB1 and
CB2 receptors
Receptor may refer to:
*Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse
*Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a n ...
, with
''K''i values of 1.5 nM at CB
1 and 0.32 nM at CB
2.
See also
*
O-2113
O-2113 is a drug that is a classical cannabinoid derivative, which acts as a potent agonist for cannabinoid receptors, producing sedation, hypothermia and analgesia
Pain management is an aspect of medicine and health care involving relief ...
*
O-2372
O-2372 is an analgesic cannabinoid derivative created by Organix Inc. for use in scientific research. It has high affinity for both CB1 and CB2 receptors, with ''K''i values of 1.3 nM at CB1 and 0.57 nM at CB2, but is only moderatel ...
*
Tropoxane
Tropoxane (O-1072) is an aryloxytropane derivative drug developed by Organix Inc., which acts as a stimulant and potent dopamine and serotonin reuptake inhibitor. It is an analogue of dichloropane where the amine nitrogen has been replaced by an ...
References
{{cannabinoid-stub
Cannabinoids
Benzochromenes
Phenols
Imidazoles