The Nottingham prognostic index (NPI) is used to determine prognosis following surgery for breast cancer.
Its value is calculated using three pathological criteria: the size of the tumour; the number of involved lymph nodes; and the Grading (tumors), grade of the tumour.
It is calculated to select patients for adjuvant treatment.
Calculation
The index is calculated using the formula:
:NPI = [0.2 x S] + N + G
Where:
* S is the size of the index lesion in centimetres
* N is the node status: 0 nodes = 1, 1-3 nodes = 2, >3 nodes = 3
* G is the grade of tumour: Grade I =1, Grade II =2, Grade III =3
Interpretation
References
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External links
Online calculator based on Todd et al, 1987 studyThe Nottingham Prognostic Index Biomedical Informatics Research GroupNottingham prognostic index Ganfyd
Breast cancer
Diagnostic obstetrics and gynaecology
Health in Nottinghamshire
Science and technology in Nottinghamshire
University of Nottingham