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Lymph Node
A lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system. A large number of lymph nodes are linked throughout the body by the lymphatic vessels. They are major sites of lymphocytes that include B and T cells. Lymph nodes are important for the proper functioning of the immune system, acting as filters for foreign particles including cancer cells, but have no detoxification function. In the lymphatic system, a lymph node is a secondary lymphoid organ. A lymph node is enclosed in a fibrous capsule and is made up of an outer cortex and an inner medulla. Lymph nodes become inflamed or enlarged in various diseases, which may range from trivial throat infections to life-threatening cancers. The condition of lymph nodes is very important in cancer staging, which decides the treatment to be used and determines the prognosis. Lymphadenopathy refers to glands that are enlarged or swollen. When inflamed or enlarged, lymph nodes can ...
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Lymphatic Vessel
The lymphatic vessels (or lymph vessels or lymphatics) are thin-walled vessels (tubes), structured like blood vessels, that carry lymph. As part of the lymphatic system, lymph vessels are complementary to the cardiovascular system. Lymph vessels are lined by endothelium, endothelial cells, and have a thin layer of smooth muscle, and adventitia that binds the lymph vessels to the surrounding tissue. Lymph vessels are devoted to the propulsion of the lymph from the lymph capillaries, which are mainly concerned with the absorption of interstitial fluid from the tissues. Lymph capillaries are slightly bigger than their counterpart capillary, capillaries of the vascular system. Lymph vessels that carry lymph to a lymph node are called afferent lymph vessels, and those that carry it from a lymph node are called efferent lymph vessels, from where the lymph may travel to another lymph node, may be returned to a vein, or may travel to a larger lymph duct. Lymph ducts drain the lymph into ...
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Axillary Lymph Nodes
The axillary lymph nodes or armpit lymph nodes are lymph nodes in the human armpit. Between 20 and 49 in number, they drain lymph vessels from the lateral quadrants of the breast, the superficial lymph vessels from thin walls of the chest and the abdomen above the level of the navel, and the vessels from the upper limb. They are divided in several groups according to their location in the armpit. These lymph nodes are clinically significant in breast cancer, and metastases from the breast to the axillary lymph nodes are considered in the Cancer staging, staging of the disease. Structure The axillary lymph nodes are arranged in six groups: #Pectoral axillary lymph nodes, Anterior (pectoral) group: Lying along the lower border of the pectoralis minor behind the pectoralis major, these nodes receive lymph vessels from the lateral quadrants of the breast and superficial vessels from the anterolateral abdominal wall above the level of the umbilicus. #Subscapular axillary lymph nodes, ...
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Grammatical Number
In linguistics, grammatical number is a Feature (linguistics), feature of nouns, pronouns, adjectives and verb agreement (linguistics), agreement that expresses count distinctions (such as "one", "two" or "three or more"). English and many other languages present number categories of singular or plural. Some languages also have a Dual (grammatical number), dual, #Trial, trial and #Paucal, paucal number or other arrangements. The word "number" is also used in linguistics to describe the distinction between certain grammatical aspects that indicate the number of times an event occurs, such as the semelfactive aspect, the iterative aspect, etc. For that use of the term, see "Grammatical aspect". Overview Most languages of the world have formal means to express differences of number. One widespread distinction, found in English and many other languages, involves a simple two-way contrast between singular and plural number (''car''/''cars'', ''child''/''children'', etc.). Discussion ...
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Blood–brain Barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane, semipermeable border of endothelium, endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. The blood–brain barrier is formed by endothelial cells of the Capillary, capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane. This system allows the passage of some small molecules by passive transport, passive diffusion, as well as the selective and active transport of various nutrients, ions, organic anions, and macromolecules such as glucose and amino acids that are crucial to neural function. The blood–brain barrier restricts the passage of pathogens, the diffusion of solutes in the blood, and Molecular mass, large or Hydrophile, hydrophilic molecules into the cerebrospinal fluid, while a ...
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Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilateria, bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and Coelenterata, diploblasts. It is a structure composed of nervous tissue positioned along the Anatomical_terms_of_location#Rostral,_cranial,_and_caudal, rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain, though precursor structures exist in onychophorans, gastropods and lancelets. The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal ...
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Tracheobronchial Lymph Nodes
The tracheobronchial lymph nodes are lymph nodes that are located around the division of trachea and main bronchi. Structure These lymph nodes form four main groups including paratracheal, tracheobronchial, bronchopulmonary and pulmonary nodes. # ''Paratracheal nodes'' are located on either side of the trachea. # ''Tracheobronchial nodes'' can be divided into three nodes including left and right superior tracheobronchial nodes, and the inferior trachiobronchial node. The two superior tracheobronchial nodes are located on either side of trachea just before its bifurcation. The inferior tracheobronchial node is located just below the bifurcation in the angle between the two bronchi. # ''Bronchopulmonary nodes'' (hilar nodes) situate in the hilum of each lung. # ''Pulmonary nodes'' are embedded the lung substance on the larger branches of the bronchi. The ''afferents'' of the tracheobronchial glands drain the lungs and bronchi, the thoracic part of the trachea and the hear ...
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Paraaortic Lymph Nodes
The periaortic lymph nodes (also known as lumbar) are a group of lymph nodes that lie in front of the lumbar vertebrae near the aorta. These lymph nodes receive drainage from the gastrointestinal tract and the abdominal organs. The periaortic lymph nodes are different from the paraaortic lymph nodes. The periaortic group is the general group, that is subdivided into: preaortic, paraaortic, and retroaortic groups. The paraaortic group is synonymous with the lateral aortic group. Divisions The periaortic lymph node group is divided into three subgroups: preaortic, paraaortic, and retroaortic: * The preaortic group drains the gastrointestinal viscera. They can be subdivided into three groups: the celiac nodes, the superior mesenteric nodes, and the inferior mesenteric nodes. *The paraaortic group (also known as lateral aortic group) drains the iliac nodes, the ovaries, the testes and other pelvic organs. The lateral group nodes are located adjacent to the aorta, anterior to th ...
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Inguinal Lymph Nodes
Inguinal lymph nodes are lymph nodes in the groin. They are situated in the femoral triangle of the inguinal region. They are subdivided into two groups: the superficial inguinal lymph nodes and deep inguinal lymph nodes. Superficial inguinal lymph nodes The superficial inguinal lymph nodes are the inguinal lymph nodes that form a chain immediately inferior to the inguinal ligament. They lie deep to the fascia of Camper that overlies the femoral vessels at the medial aspect of the thigh. They are bounded superiorly by the inguinal ligament in the femoral triangle, laterally by the border of the sartorius muscle, and medially by the adductor longus muscle. There are approximately 10 superficial lymph nodes. They normally measure up to 2 cm in diameter. Last updated: Last updated: Feb 16, 2017 They are divided into three groups: * inferior – inferior of the saphenous opening of the leg, receive drainage from lower legs * superolateral – on the side of the saphenous open ...
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Cervical Lymph Nodes
Cervical lymph nodes are lymph nodes found in the neck. Of the 800 lymph nodes in the human body, 300 are in the neck. Cervical lymph nodes are subject to a number of different pathological conditions including tumours, infection and inflammation. Classification There are approximately 300 lymph nodes in the neck, and they can be classified in a number of different ways. History The classification of the cervical lymph nodes is generally attributed to Henri Rouvière in his 1932 publication "Anatomie des Lymphatiques de l'Homme" Rouviere described the cervical lymph nodes as a collar which surrounded the upper aerodigestive tract, consisting of submental, facial, submandibular, parotid, mastoid, occipital and retropharyngeal nodes, together with two chains that run in the long axis of the neck, the anterior cervical and postero-lateral cervical groups. However, this system was based upon anatomical landmarks found in dissection, making it imperfectly suited to the n ...
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Hilum (anatomy)
In human anatomy, the hilum (; : hila), sometimes formerly called a hilus (; : hili), is a depression or fissure where structures such as blood vessels and nerves enter an Organ (anatomy), organ. Examples include: * Hilum of kidney, admits the renal artery, renal vein, vein, ureter, and nerves * Splenic hilum, on the surface of the spleen, admits the splenic artery, splenic vein, vein, lymph vessels, and nerves * Hilum of lung, a triangular depression where the structures which form the root of the lung enter and leave the Organ (biology)#Viscera, viscus * Hilum of lymph node, the portion of a lymph node where the Efferent lymphatic vessel, efferent vessels exit * Hippocampus proper#CA4, Hilus of dentate gyrus, part of hippocampus that contains the Mossy fiber (hippocampus), mossy cells. ...
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Trabecula
A trabecula (: trabeculae, from Latin for 'small beam') is a small, often microscopic, biological tissue, tissue element in the form of a small Beam (structure), beam, strut or rod that supports or anchors a framework of parts within a body or organ. A trabecula generally has a mechanical function, and is usually composed of dense collagenous tissue (such as the trabeculae of spleen, trabecula of the spleen). It can be composed of other material such as muscle and bone. In the heart, muscles form trabeculae carneae and septomarginal trabecula, septomarginal trabeculae, and the left atrial appendage has a tubular trabeculated structure. Bone#Trabeculae, Cancellous bone is formed from groupings of trabeculated bone tissue. In cross section, trabeculae of a Bone#Trabeculae, cancellous bone can look like septum, septa, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. When crossing fluid-filled ...
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