JOHNSON & JOHNSON is an American multinational medical devices ,
pharmaceutical and consumer packaged goods manufacturing company
founded in 1886. Its common stock is a component of the Dow Jones
Industrial Average and the company is listed among the
Johnson & Johnson is headquartered in
New Brunswick, New Jersey , the
consumer division being located in Skillman,
Johnson & Johnson's brands include numerous household names of medications and first aid supplies. Among its well-known consumer products are the Band-Aid Brand line of bandages , Tylenol medications, Johnson\'s baby products, Neutrogena skin and beauty products , Clean & Clear facial wash and Acuvue contact lenses .
* 1 History
* 1.7 Ethicon, Inc
* 1.7.1 Ethicon Endo-Surgery, Inc.
* 2 Corporate governance
* 3 JNJ Headquarters and the New Brunswick gentrification
* 3.1 Chairmen
* 4 Products
* 4.1 Pharmaceuticals * 4.2 Medical devices * 4.3 Consumer health
* 5 Environmental record
* 6 Recalls and litigation
* 6.1 1982
Chicago Tylenol murders
* 6.2 2010 children\'s product recall
* 6.3 2010 hip-replacement recall
* 6.4 2010 Tylenol recall
* 7 See also * 8 References * 9 External links
Johnson & Johnson operates over 250 companies in what is termed "the Johnson Consumer Healthcare, Medical Devices and Pharmaceuticals.
JOHNSON & JOHNSON FAMILY OF COMPANIES
CONSUMER HEALTHCARE MEDICAL DEVICES PHARMACEUTICALS
Baby Care Skin & Hair Care Wound Care and Topicals Oral Health Care Women’s Health McNeil Consumer Healthcare Over-The-Counter Medicines Nutritionals Advanced Sterilization Products Animas Corporation Biosense Webster DePuy Synthes Companies of Johnson & Johnson Ethicon, Inc. Janssen Diagnostics BVBA Johnson & Johnson Vision Care, Inc. LifeScan, Inc. Mentor Janssen Janssen R"> Robert Wood Johnson
Inspired by a speech by antiseptic advocate Joseph Lister , Robert Wood Johnson joined his brothers James Wood Johnson and Edward Mead Johnson to create a line of ready-to-use surgical dressings in 1885. The company produced its first products in 1886 and incorporated in 1887.
Robert Wood Johnson served as the first president of the company. He worked to improve sanitation practices in the nineteenth century, and lent his name to a hospital in New Brunswick, New Jersey . Upon his death in 1910, he was succeeded in the presidency by his brother James Wood Johnson until 1932, and then by his son, Robert Wood Johnson II .
Robert Wood Johnson's granddaughter, Mary Lea Johnson Richards , was the first baby to appear on a Johnson ">
1959: MCNEIL CONSUMER HEALTHCARE
McNeil Consumer Healthcare was founded on March 16, 1879 by
23-year-old Robert McNeil. In 1904, one of McNeil's sons, Robert
Lincoln McNeil, became part of the company and together they created
McNeil Laboratories in 1933. The company focused on direct marketing
of prescription drugs to hospitals, pharmacists, and doctors.
Development of acetaminophen began under the leadership of Robert L.
McNeil, Jr. , who later served as the firm's chairman. In 1959,
Johnson McNeil medicals products and McNeil Consumer Products Company
(also known as McNeil Consumer Healthcare). The focus of McNeil
medicals products is to market prescription drugs. In 1993 McNeil
medicals products merged with the
Ortho Pharmaceutical to form
In 1933, Swiss chemist
Bernhard Joos set up a small research
1961: JANSSEN PHARMACEUTICALS
Janssen Pharmaceuticals can be traced back to 1933. In 1933 Constant
Janssen , the father of Paul Janssen, acquired the right to distribute
the pharmaceutical products of Richter , a Hungarian pharmaceutical
company, for Belgium, the
Paul Janssen founded his own research laboratory in 1953 on the third
floor of the building in the Statiestraat, still within the
Richter-Eurpharma company of his father. On 5 April 1956, the name of
the company was changed to NV Laboratoria Pharmaceutica C. Janssen
(named after Constant Janssen). On 2 May 1958, the research department
in Beerse became a separate legal entity, the N.V. Research
Laboratorium C. Janssen. On 24 October 1961, the company was acquired
by the American corporation Johnson & Johnson. On 10 February 1964,
the name was changed to
Janssen Pharmaceutica N.V. Between 1990 and
Janssen Pharmaceuticals expanded worldwide, with the company
grew in size to approximately 28000 employees worldwide. In 1999,
clinical research and non-clinical development become a global
organization within Johnson & Johnson. In 2001, part of the research
activities was transferred to the
In August 2013, the company acquired Aragon Pharmaceuticals, Inc. . In November 2014, the company acquired Alios BioPharma, Inc. for $1.75 billion. As a result of the purchase, Alios was incorporated into the infectious diseases therapeutic area of the Janssen Pharmaceutical Companies of Johnson & Johnson. In March 2015, Janssen licensed Tipofarnib (a farnesyl transferase inhibitor) to Kura Oncology who will assume sole responsibility for developing and commercialising the anti-cancer drug. Later in the same month the company announced that Galapagos Pharma and regained the rights to the anti-inflammatory drug candidate GLPG1690 as well as two other compounds including GLPG1205 (a first-in-class inhibitor of GPR84 ). Finally, in March, the company acquired XO1 Limited In November 2015, the company acquired Novira Therapeutics, Inc. , gaining the lead candidate, NVR 3-778 .
DePuy was acquired by J&J in 1998, rolling it into the Johnson & Johnson Medical Devices group. On June 14, 2012, Johnson and Johnson completed the acquisition of Synthes for $19.7 billion, which was then integrated with the DePuy franchise to establish the DePuy Synthes Companies of Johnson Codman DePuy Ireland Unlimited Company announced it would acquire Neuravi, a company with a portfolio of products for hemorrhagic and ischemic strokes for an undisclosed sum, with Codman Neuro being behind the deal. In June, DePuy Synthes Products, Inc. announced it would acquire Innovative Surgical Solutions, LLC (trading as Sentio, LLC) for an undisclosed sum, bolstering the company's technology for innovative nerve localisation in spinal surgery.
1999: JANSSEN BIOTECH, INC.
Janssen Biotech, Inc., formerly known as
Centocor Biotech, Inc., is a
biotechnology company that was founded in
George F. Merson opened a facility in Edinburgh for the
manufacturing, packaging and sterilizing of catgut, silk and nylon
Johnson & Johnson acquired Mr. Merson’s company in 1947,
and this was renamed Ethicon Suture Laboratories. In 1953 this became
Ethicon Inc. In 1992, Ethicon was restructured, and Ethicon
Endo-Surgery, Inc. became a separate corporate entity . During the
1990s, Ethicon diversified into new and advanced products and
technologies and formed four different companies under the Ethicon
umbrella, each of which specialize in different products. In 2008 J&J
announced it would acquire Mentor
Ethicon Endo-Surgery, Inc.
In January 2017, J&J fought off competition from
JOHNSON & JOHNSON VISION CARE, INC
In July 2016, J&J announced its intention to acquire the privately held company, Vogue International LLC, boosting Johnson & Johnson Consumer Inc. In September of the same year, J&J announced it would acquire Abbott Medical Optics from Abbott Laboratories for $4.325 billion, adding the new division into Johnson & Johnson Vision Care, Inc.
In July 2017, Johnson & Johnson Vision Care, Inc announced that its Abbott Medical Optics subsidiary would acquire TearScience , who recently received FDA approval for an office-based approach to imaging meibomian glands and treating meibomian gland dysfunction .
In October 2010, J"> J"> Johnson & Johnson office in Ontario
The following is an illustration of the company's structure, maintained though a number of mergers ">JOHNSON padding:0;">
Skin border-left:1px solid;vertical-align:top;text-align:center;">
Wound Care and Topicals
Oral Health Care
Vogue International LLC
Medical Devices Division
Advanced Sterilization Products
Coherex Medical, Inc.
Pulsar Vascular Inc.
DePuy Mitek, Inc.
DePuy Orthopaedics, Inc.
Biomedical Enterprises, Inc.
DePuy Spine, Inc
NeuWave Medical, Inc
Megadyne Medical Products, Inc.
Janssen Diagnostics BVBA
Abbott Medical Optics
Aragon Pharmaceuticals, Inc.
Alios BioPharma, Inc.
Novira Therapeutics, Inc.
Janssen Rborder-left:1px solid;vertical-align:top;text-align:center;">
Janssen Healthcare Innovation
Janssen Biotech, Inc.
Ortho Biotech Inc.
Janssen Scientific Affairs
McNeil Nutritional LLC
Mead Johnson (Sold to Reckitt Benckiser)
Current members of the board of directors of Johnson & Johnson are: Mary Sue Coleman , James G. Cullen, Dominic Caruso, Michael M.E. Johns, Ann Dibble Jordan , Arnold G. Langbo, Susan L. Lindquist , Leo F. Mullin, William Perez , Steven S. Reinemund, David Satcher , and William C. Weldon .
JNJ HEADQUARTERS AND THE NEW BRUNSWICK GENTRIFICATION
The company has historically been located on the Delaware and Raritan Canal in New Brunswick. The company considered moving its headquarters out of New Brunswick in the 1960s, but decided to stay in the town after city officials promised to gentrify downtown New Brunswick by demolishing old buildings and constructing new ones.
While New Brunswick lost at least one historic edifice (the inn where
The company's CNS products include the ADHD drug Concerta (methylphenidate extended release), and the long-acting injectable antipsychotics Invega Sustenna (paliperidone palmitate ) and Risperdal Consta (risperidone ). Invega Sustenna and Risperdal Consta were the first widely utilized long-acting depot injections for the treatment of schizophrenia. Designed to address the issue of poor patient compliance with oral therapy, they are administered by intramuscular injection at intervals of 2 weeks and one month, respectively. Only minimal improvements in outcomes relative to the oral versions of these drugs were observed in the clinical trial setting, but some evidence suggests that the advantages of long-acting injections in clinical practice may be greater than is readily demonstrated in the environment of a clinical trial.
Oncology products include Velcade (bortezomib ), for the treatment of multiple myeloma and mantle cell lymphoma and Zytiga (abiraterone ), an androgen antagonist for the treatment of prostate cancer. In clinical trials, abiraterone treatment was associated with a 4.6 to 5.2 survival advantage when used either before or after chemotherapy with platinum based drugs. On December 31, 2012, the Food and Drug Administration approved Sirturo (bedaquiline), a Johnson -webkit-column-count: 2; column-count: 2;">
Sectors in which the company is active include:
* Aesthetics (Ethicon, Mentor) * Arrhythmias (Biosense Webster) * Bariatric Surgery for Obesity (Ethicon) * Cardiovascular Disease (Biosense Webster, Inc.) * Diabetes Care (LifeScan, Animas Corporation) * Ear, Nose, and Throat Conditions (Acclarent) * General Surgery (Ethicon, Codman Neuro) * Hernia Surgery (Ethicon) * Insulin Delivery Devices (Animas) * Neurovascular Disease (Codman Neuro, DePuy Synthes) * Orthopaedics ( DePuy Synthes): Joint Reconstruction, Trauma, Spine, Sports Medicine and Power Tools * Self-Measured Blood Glucose Monitors (LifeScan) * Surgical Instruments and Infection Prevention(Advanced Sterilization Products) * Urologic Surgery (Ethicon) * Vision Care (VISTAKON®)
Sectors in which the company is active include:
* Baby Care * Nutritionals * Oral Health Care * Over-the-Counter Medicines * Skin & Hair Care * Vision Care * Wound Care & Topicals
Johnson & Johnson has set several positive goals to keep the company environmentally friendly and was ranked third among the United States's largest companies in Newsweek's "Green Rankings". Some examples are the reduction in water use, waste, and energy use and an increased level of transparency. Johnson & Johnson agreed to change its packaging of plastic bottles used in the manufacturing process, switching their packaging of liquids to non-polycarbonate containers. The corporation is working with the Climate Northwest Initiative and the EPA National Environmental Performance Track program. As a member of the national Green Power Partnership, Johnson & Johnson operates the largest solar power generator in Pennsylvania at its site in Spring House, PA .
RECALLS AND LITIGATION
1982 CHICAGO TYLENOL MURDERS
Main article: Chicago Tylenol murders
On September 29, 1982, a "Tylenol scare" began when the first of
seven individuals died in
Chicago metropolitan area
2010 CHILDREN\'S PRODUCT RECALL
Main article: 2010 Johnson & Johnson children\'s product recall
On April 30, 2010,
McNeil Consumer Healthcare , a subsidiary of
Johnson and Johnson, voluntarily recalled 43 over-the-counter
children's medicines, including Tylenol , Tylenol Plus,
2010 HIP-REPLACEMENT RECALL
Main article: 2010 DePuy Hip Recall
On August 2009, 2010, DePuy, a subsidiary of American giant Johnson & Johnson, recalled its ASR (articular surface replacement) hip prostheses from the market. DePuy said the recall was due to unpublished National Joint Registry data showing a 12% revision rate for resurfacing at five years and an ASR XL revision rate of 13%. All hip prostheses fail in some patients, but it is expected that the rate will be about 1% a year. Pathologically, the failing prosthesis had several effects. Metal debris from wear of the implant led to a reaction that destroyed the soft tissues surrounding the joint, leaving some patients with long term disability. Ions of cobalt and chromium—the metals from which the implant was made—were also released into the blood and cerebral spinal fluid in some patients.
In March 2013, a jury in Los Angeles ordered Johnson & Johnson to pay more than $8.3 million in damages to a Montana man in the first of more than 10,000 lawsuits pending against the company in connection with the now-recalled DePuy hip.
Some lawyers and industry analysts have estimated that the suits ultimately will cost Johnson & Johnson billions of dollars to resolve.
2010 TYLENOL RECALL
In 2010 and 2011, Johnson & Johnson voluntarily recalled some over-the-counter products including Tylenol due to an odor caused by tribromoanisole. In this case, 2,4,6-tribromophenol was used to treat wooden pallets on which product packaging materials were transported and stored.
In 2010 a group of shareholders sued the board for allegedly failing to take action to prevent serious failings and illegalities since the 1990s, including manufacturing problems, bribing officials, covering up adverse effects and misleading marketing for unapproved uses. The judge initially dismissed the case in September 2011, but allowed the plaintiffs opportunity to refile at a later time. In 2012 Johnson and Johnson proposed a settlement with the shareholders, whereby the company would institute new oversight, quality and compliance procedures binding for five years.
ILLEGAL MARKETING OF RISPERDAL
Juries in several US states have found J&J guilty of concealing the adverse effects of Janssen Pharmaceuticals ' antipsychotic medication Risperdal , produced by its unit, in order to promote it to doctors and patients as better than cheaper generics, and of falsely marketing it for treating patients with dementia. States that have awarded damages include Texas ($158 million), South Carolina ($327 million), Louisiana ($258 million), and most notably Arkansas ($1.2 billion).
In 2010, the
Johnson & Johnson has also been subject to congressional investigations related to payments given to psychiatrists to promote its products and ghost write articles, notably Joseph Biederman and his pediatric bipolar disorder research unit.
In 2011, J&J settled litigation brought by the US Securities and Exchange Commission under the Foreign Corrupt Practices Act and paid around $70M in disgorgement and fines. J&J's employees had given kickbacks and bribes to doctors in Greece, Poland, and Romania to obtain business selling drugs and medical devices and had bribed officials in Iraq to win contracts under the Oil for Food program. J&J fully cooperated with the investigation once the problems came to light.
CONSUMER FRAUD SETTLEMENTS
Johnson & Johnson registered the
A declaration made by the U.S. upon its ratification of the 1949
In August 2007,
Johnson & Johnson filed a lawsuit against the
BOSTON SCIENTIFIC LAWSUITS
Johnson & Johnson and
PATENT-INFRINGEMENT CASE AGAINST ABBOTT
In 2007, Johnson & Johnson sued Abbott Laboratories over the development and sale of the arthritis drug Humira . Johnson & Johnson claimed that Abbott used technology patented by New York University and licensed exclusively to Johnson & Johnson's Centocor division to develop Humira. Johnson & Johnson won the court case, and in 2009 Abbott was ordered to pay Johnson & Johnson $1.17 billion in lost revenues and $504 million in royalties. The judge also added $175.6 million in interest to bring the total to $1.84 billion. This was the largest patent-infringement award in U.S. history until the 2013 decision against Teva in favor of Takeda and Pfizer for over 2.1 billion dollars. Abbott has since successfully reversed the verdict at appeal.
In February 2016, J&J was ordered to pay $72 million in damages to the family of Jacqueline Fox, a 62-year-old woman who died of ovarian cancer in 2015. She had been sprinkling Johnson's Baby Powder on her underwear nearly every day since she was a teenager. J&J claimed that the safety of cosmetic talc is supported by decades of scientific evidence and it plans to appeal the verdict. The British charity, Ovacome was quoted as saying that while there were 16 studies which showed that using talc increased the risk of ovarian cancer by around a third and that a 2013 review of US studies came up with similar results for genital, but not general talcum powder use, J&J were not convinced that the results were reliable. Furthermore, Ovacome said, " Ovarian cancer is a rare disease, and increasing a small risk by a third still gives a small risk."
By March 2017, over 1,000 U.S. women had sued J the company says that 70 percent of its Baby Powder is used by adults.
* Frederick Barnett Kilmer – Director of Scientific Laboratories from 1889 to 1934. * Zodiac – Historic schooner built for the Johnson family heirs.
* ^ A B C D E F "Johnson ">(XBRL).
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