Biomedical Advanced Research And Development Authority
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Biomedical Advanced Research And Development Authority
The Biomedical Advanced Research and Development Authority (BARDA) is a U.S. Department of Health and Human Services (HHS) office responsible for the procurement and development of medical countermeasures, principally against bioterrorism, including chemical, biological, radiological and nuclear (CBRN) threats, as well as pandemic influenza and emerging diseases. BARDA was established in 2006 through the Pandemic and All-Hazards Preparedness Act (PAHPA) and reports to the Office of the Assistant Secretary for Preparedness and Response (ASPR). The office manages Project BioShield, which funds the research, development and stockpiling of vaccines and treatments that the government could use during public health emergencies such as chemical, biological, radiological or nuclear (CBRN) attacks. In addition to preparing and maintaining bioterrorism responses and countermeasures, HHS, through the ASPR and BARDA, prepares and maintains an integrated system of medical countermeasu ...
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United States Dollars
The United States dollar (Currency symbol, symbol: Dollar sign, $; ISO 4217, code: USD; also abbreviated US$ or U.S. Dollar, to distinguish it from Dollar, other dollar-denominated currencies; referred to as the dollar, U.S. dollar, American dollar, or colloquially buck) is the official currency of the United States and International use of the U.S. dollar, several other countries. The Coinage Act of 1792 introduced the U.S. dollar at par with the Spanish dollar, Spanish silver dollar, divided it into 100 cent (currency), cents, and authorized the minting of coins denominated in dollars and cents. U.S. banknotes are issued in the form of Federal Reserve Notes, popularly called greenbacks due to their predominantly green color. The monetary policy of the United States is conducted by the Federal Reserve System, which acts as the nation's central bank. The U.S. dollar was originally defined under a bimetallism, bimetallic standard of (0.7735 troy ounces) fine silver or, from 1 ...
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Public Health Service Act
The Public Health Service Act is a United States federal law enacted in 1944. The full act is codified in Title 42 of the United States Code (The Public Health and Welfare), Chapter 6A (Public Health Service). Contents The act clearly established the federal government's quarantine authority for the first time. It gave the United States Public Health Service responsibility for preventing the introduction, transmission and spread of communicable diseases from foreign countries into the United States. The Public Health Service Act granted the original authority for scientists and special consultants to be appointed "without regard to the civil-service laws", known as a Title 42 appointment. During COVID-19 pandemic, section has been used for Title 42 expulsion. Amendments It has since been amended many times. Some of these amendments are: *Family Planning Services and Population Research Act of 1970 , which established Title X of the Public Health Service Act, dedicated to pr ...
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Venture Capital
Venture capital (commonly abbreviated as VC) is a form of private equity financing that is provided by venture capital firms or funds to startups, early-stage, and emerging companies that have been deemed to have high growth potential or which have demonstrated high growth (in terms of number of employees, annual revenue, scale of operations, etc). Venture capital firms or funds invest in these early-stage companies in exchange for equity, or an ownership stake. Venture capitalists take on the risk of financing risky start-ups in the hopes that some of the companies they support will become successful. Because startups face high uncertainty, VC investments have high rates of failure. The start-ups are usually based on an innovative technology or business model and they are usually from high technology industries, such as information technology (IT), clean technology or biotechnology. Typical venture capital investments occur after an initial "seed funding" round. The first ro ...
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Emergency Use Authorization
An Emergency Use Authorization (EUA) in the United States is an authorization granted to the Food and Drug Administration (FDA) under sections of the Federal Food, Drug, and Cosmetic Act as added to and amended by various Act of Congress, Acts of Congress, including by the Pandemic and All-Hazards Preparedness Reauthorization Act of 2013 (PAHPRA), as codified by , to allow the use of a drug prior to approved drug, approval. It does not constitute ''approval'' of the drug in the full statutory meaning of the term, but instead authorizes the FDA to facilitate availability of an unapproved product, or an unapproved use of an approved product, during a declared state of emergency from one of several agencies or of a "material threat" by the Secretary of Homeland Security. Use EUAs have historically been infrequent. A review article by Rizk et al. provides a summary of the US experience in 2020 with pharmacological EUA approvals during the COVID-19 pandemic. It also provides a descripti ...
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Food And Drug Administration
Food is any substance consumed by an organism for nutritional support. Food is usually of plant, animal, or fungal origin, and contains essential nutrients, such as carbohydrates, fats, proteins, vitamins, or minerals. The substance is ingested by an organism and assimilated by the organism's cells to provide energy, maintain life, or stimulate growth. Different species of animals have different feeding behaviours that satisfy the needs of their unique metabolisms, often evolved to fill a specific ecological niche within specific geographical contexts. Omnivorous humans are highly adaptable and have adapted to obtain food in many different ecosystems. The majority of the food energy required is supplied by the industrial food industry, which produces food with intensive agriculture and distributes it through complex food processing and food distribution systems. This system of conventional agriculture relies heavily on fossil fuels, which means that the food and agricultural ...
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Business Accelerator
Startup accelerators, also known as seed accelerators, are fixed-term, Cohort (educational group), cohort-based programs, that include mentorship and educational components and culminate in a public sales pitch, pitch event or demo day. While traditional business incubators are often government-funded, generally take no equity, and rarely provide funding, accelerators can be either privately or publicly funded and cover a wide range of industries. Unlike business incubators, the application process for seed accelerators is open to anyone but highly competitive. There are specific accelerators, such as corporate accelerators, which are often subsidiaries or programs of larger corporations that act like seed accelerators. Distinctive qualities The main differences between business incubators, startup studios, and accelerators are: # The application process is open to anyone but highly competitive. Y Combinator (company), Y Combinator and TechStars have application acceptance rates be ...
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COVID-19 Pandemic In The United States
The COVID-19 pandemic in the United States is a part of the COVID-19 pandemic, worldwide pandemic of COVID-19, coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the United States, it has resulted in confirmed cases with all-time deaths, the most of any country, and COVID-19 pandemic death rates by country, the twentieth-highest per capita worldwide. The COVID-19 pandemic ranks first on the list of disasters in the United States by death toll; it was the third-leading cause of death in the U.S. in 2020, behind heart disease and cancer. From 2019 to 2020, U.S. life expectancy dropped by 3years for Hispanic and Latino Americans, 2.9years for African Americans, and 1.2years for white Americans. These effects persisted as U.S. deaths due to COVID-19 in 2021 exceeded those in 2020, and life expectancy continued to fall from 2020 to 2021. On December 31, 2019, China announced the discovery of a cluster of pne ...
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Rick Bright
Rick Arthur Bright is an American immunologist, vaccine researcher, and public health official. He was the director of the Biomedical Advanced Research and Development Authority (BARDA) from 2016 to 2020. In May 2020, he filed a whistleblower complaint, alleging that the Trump administration ignored his early warnings about the COVID-19 pandemic and illegally retaliated against him by ousting him from his role and demoting him to a position at the National Institutes of Health. On October 6, 2020, Bright resigned from the government. On November 9 he was named a member of President-elect Joe Biden's coronavirus advisory board. Early life Bright was born and raised in Hutchinson, Kansas. In 1984, he graduated from Hutchinson High School. Following two years at the University of Kansas, he received a Bachelor of Science degree with a double major in biology (medical technology) and physical science (chemistry) from Auburn University-Montgomery. His undergraduate academic adv ...
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Pandemic And All-Hazards Preparedness And Advancing Innovation Act
A pandemic () is an epidemic of an infectious disease that has spread across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. A widespread endemic disease with a stable number of infected individuals is not a pandemic. Widespread endemic diseases with a stable number of infected individuals such as recurrences of seasonal influenza are generally excluded as they occur simultaneously in large regions of the globe rather than being spread worldwide. Throughout human history, there have been a number of pandemics of diseases such as smallpox. The most fatal pandemic in recorded history was the Black Death—also known as The Plague—which killed an estimated 75–200 million people in the 14th century. The term had not been used then but was used for later epidemics, including the 1918 influenza pandemic—more commonly known as the Spanish flu. Current pandemics include HIV/AIDS and COVID-19. Definition A pand ...
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Pandemic And All-Hazards Preparedness Reauthorization Act Of 2013
The Pandemic and All-Hazards Preparedness Reauthorization Act of 2013 () is a law enacted by the 113th United States Congress. The Act amends the Public Health Service Act in order to extend, fund, and improve several programs designed to prepare the United States and health professionals in the event of a pandemic, epidemic, or biological, chemical, radiological, or nuclear accident or attack. The Act clarifies the authority of different American officials, makes it easier to temporarily reassign personnel to respond to emergency situations, and alters the process for testing and producing medical countermeasures. The Act is focused on improving preparedness for any public health emergency. Background The Pandemic and All-Hazards Preparedness Reauthorization Act (PAHPRA) of 2013 is a follow-up bill to both the Project Bioshield Act of 2004 and the Pandemic and All-Hazards Preparedness Act of 2006. These acts were focused on preparing the country to deal with possible Ch ...
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September 11 Attacks
The September 11 attacks, commonly known as 9/11, were four coordinated suicide terrorist attacks carried out by the militant Islamist extremist network al-Qaeda against the United States on September 11, 2001. That morning, 19 terrorists hijacked four commercial airliners scheduled to travel from the New England and Mid-Atlantic regions of the East Coast to California. The hijackers crashed the first two planes into the Twin Towers of the World Trade Center in New York City, two of the top five tallest buildings in the world at the time. The hijackers aimed the next two flights toward targets in the Washington metropolitan area as part of a similarly coordinated attack on the nation's capital, and successfully flew the third plane into the Pentagon, the headquarters of the U.S. Department of Defense in Arlington County, Virginia. The fourth was intended to strike a nearby federal government building in Washington, D.C., but crashed in rural Pennsylvania following a passe ...
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2001 Anthrax Attacks
The 2001 anthrax attacks, also known as Amerithrax (a portmanteau of "America" and "anthrax", from its FBI case name), occurred in the United States over the course of several weeks beginning on September 18, 2001, one week after the September 11 terrorist attacks. Letters containing anthrax spores were mailed to several news media offices and to Democratic Senators Tom Daschle and Patrick Leahy, killing five people and infecting 17 others. According to the FBI, the ensuing investigation became "one of the largest and most complex in the history of law enforcement". A major focus in the early years of the investigation was bioweapons expert Steven Hatfill, who was eventually exonerated. Bruce Edwards Ivins, a scientist at the government's biodefense labs at Fort Detrick in Frederick, Maryland, became a focus around April 4, 2005. On April 11, 2007, Ivins was put under periodic surveillance and an FBI document stated that he was "an extremely sensitive suspect in the 2001 anthrax ...
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