Hawaiian baby woodrose
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''Argyreia nervosa'' is a
perennial A perennial plant or simply perennial is a plant that lives more than two years. The term ('' per-'' + '' -ennial'', "through the years") is often used to differentiate a plant from shorter-lived annuals and biennials. The term is also widel ...
climbing
vine A vine (Latin ''vīnea'' "grapevine", "vineyard", from ''vīnum'' "wine") is any plant with a growth habit of trailing or scandent (that is, climbing) stems, lianas or runners. The word ''vine'' can also refer to such stems or runners themsel ...
native to the
Indian subcontinent The Indian subcontinent is a physiographical region in Southern Asia. It is situated on the Indian Plate, projecting southwards into the Indian Ocean from the Himalayas. Geopolitically, it includes the countries of Bangladesh, Bhutan, In ...
and introduced to numerous areas worldwide, including
Hawaii Hawaii ( ; haw, Hawaii or ) is a state in the Western United States, located in the Pacific Ocean about from the U.S. mainland. It is the only U.S. state outside North America, the only state that is an archipelago, and the only stat ...
,
Africa Africa is the world's second-largest and second-most populous continent, after Asia in both cases. At about 30.3 million km2 (11.7 million square miles) including adjacent islands, it covers 6% of Earth's total surface area ...
, and the
Caribbean The Caribbean (, ) ( es, El Caribe; french: la Caraïbe; ht, Karayib; nl, De Caraïben) is a region of the Americas that consists of the Caribbean Sea, its islands (some surrounded by the Caribbean Sea and some bordering both the Caribbean ...
. Though it can be invasive, it is often prized for its aesthetic and medicinal value. Common names include Hawaiian baby woodrose, adhoguda अधोगुडा or vidhara विधारा (Sanskrit), elephant creeper and woolly morning glory. Its seeds are known for their powerful entheogenic properties, greater or similar to those of
Ipomoea ''Ipomoea'' () is the largest genus in the plant family Convolvulaceae, with over 600 species. It is a large and diverse group, with common names including morning glory, water convolvulus or water spinach, sweet potato, bindweed, moonfl ...
species, with users reporting significant psychedelic and spiritual experiences. The two botanical varieties are ''A. n.'' var. ''nervosa'' described here, and ''A. n.'' var. ''speciosa'', which are used in
Ayurvedic medicine Ayurveda () is an alternative medicine system with historical roots in the Indian subcontinent. The theory and practice of Ayurveda is pseudoscientific. Ayurveda is heavily practiced in India and Nepal, where around 80% of the population repor ...
for their medicinal value. ''Argyreia nervosa'' seeds contain various
ergoline Ergoline is a chemical compound whose structural skeleton is contained in a variety of alkaloids, referred to as ergoline derivatives or ergoline alkaloids. Ergoline alkaloids, one being ergine, were initially characterized in ergot. Some of thes ...
alkaloid Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of simila ...
s such as
ergine Ergine, also known as d-lysergic acid amide (LSA) and d-lysergamide, is an ergoline alkaloid that occurs in various species of vines of the Convolvulaceae and some species of fungi. The psychedelic properties in the seeds of ololiuhqui, Hawai ...
. A study reported
stereoisomers In stereochemistry, stereoisomerism, or spatial isomerism, is a form of isomerism in which molecules have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms ...
of ergine to be found in the seeds at a concentration of 0.325% of dry weight. A more recent study reported presence of ergometrine,
lysergol Lysergol is an alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi (most within ''Claviceps''), and in the morning glory family of plants (Convolvulaceae), including the hallucinogenic seeds of ''Rivea co ...
, lysergic acid and other alkaloids that contribute to its pharmacological effects.


History

While several other plants in the family
Convolvulaceae Convolvulaceae (), commonly called the bindweeds or morning glories, is a family of about 60 genera and more than 1,650 species. These species are primarily herbaceous vines, but also include trees, shrubs and herbs. The tubers of several spe ...
, such as ''
Ipomoea corymbosa ''Ipomoea corymbosa'' is a species of morning glory, native throughout Latin America from Mexico as far south as Peru and widely naturalised elsewhere. Its common names include Christmasvine, Christmaspops, and snakeplant. Description and name ...
'' (ololiuhqui) and '' Ipomoea tricolor'' (tlitliltzin), were used in shamanic rituals of
Latin America Latin America or * french: Amérique Latine, link=no * ht, Amerik Latin, link=no * pt, América Latina, link=no, name=a, sometimes referred to as LatAm is a large cultural region in the Americas where Romance languages — languages derived ...
for centuries, ''A. nervosa'' was not traditionally used for this purpose. Its properties were first brought to attention in the 1960s.


Cultivation

Where temperatures fall below 13 °C (55 °F), ''Argyreia nervosa'' is grown in a warm
greenhouse A greenhouse (also called a glasshouse, or, if with sufficient heating, a hothouse) is a structure with walls and roof made chiefly of transparent material, such as glass, in which plants requiring regulated climatic conditions are grown.These ...
. Elsewhere, it is grown on arbours,
pergola A pergola is most commonly an outdoor garden feature forming a shaded walkway, passageway, or sitting area of vertical posts or pillars that usually support cross-beams and a sturdy open lattice, often upon which woody vines are trained. T ...
s, walls, or trees. It is often grown professionally under glass in a
loam Loam (in geology and soil science) is soil composed mostly of sand ( particle size > ), silt (particle size > ), and a smaller amount of clay (particle size < ). By weight, its mineral composition is about 40–40–20% concentration of sand–si ...
-based potting compost ( John Innes No. 3) in full light, and watered freely from spring to autumn, with a balanced liquid fertilizer applied monthly and reduced water in winter. It is grown outdoors in moderately fertile, moist but well-drained soil in full sun. Pruning is done in late winter.


Glycosides

*Argyroside, (24''R'')-ergost-5-en-11-oxo-3β-ol-α-D-glucopyranoside, a steroidal glycoside unique to ''Argyreia nervosa''


Ergolines


Hydroxycinnamic acids


Fatty acids


Entheogen

Certain
New Age New Age is a range of spiritual or religious practices and beliefs which rapidly grew in Western society during the early 1970s. Its highly eclectic and unsystematic structure makes a precise definition difficult. Although many scholars consi ...
sources claim that, according to 'various oral histories' Huna shamans used the powdered seeds to prepare an entheogenic drink. This is unlikely to reflect an authentic practice having once formed a part of traditional
Hawaiian Religion Hawaiian religion refers to the indigenous religious beliefs and practices of native Hawaiians, also known as the kapu system. Hawaiian religion is based largely on the tapu religion common in Polynesia and likely originated among the Tahitia ...
, given that ''Huna'' has been widely discredited as a culturally appropriative New Age religion invented by
Max Freedom Long Max Freedom Long (October 26, 1890 – September 23, 1971) was an American novelist and New Age author. Early life and career Max Freedom Long was born on October 26, 1890, in Sterling, Colorado to Toby Albert Long and his wife Jessie Diffendaffer ...
. The seeds of ''Argyreia nervosa'' can produce
psychoactive A psychoactive drug, psychopharmaceutical, psychoactive agent or psychotropic drug is a chemical substance, that changes functions of the nervous system, and results in alterations in perception, mood, consciousness, cognition or behavior. Th ...
effects, but it has not yet been demonstrated satisfactorily that their use as an entheogen predates the various countercultural movements of the 1960s. Given that ''A. nervosa'' is not native to Hawaii, having been introduced there from India, any Hawaiian practices involving it are unlikely to be of any antiquity. It cannot, however, be ruled out that the plant may have been utilised as an intoxicant in its native India at some time in the past, although evidence for this (if present) has not yet come to light. The seeds of ''A. nervosa'' contain ergot alkaloids varying considerably in concentration with LSA weight ranging between exactly similar looking seeds from 3 μg to 34 μg (avg 17 μg). However, in its effects, LSA is about one tenth as potent as its cousin LSD, making a threshold dose level for LSA about 500 μg. The psychoactive effects of the seeds may therefore be due to other alkaloids present in them and the safe and effective dose may be difficult to predict.


Uses in the traditional medicine of India

While he does not claim there to be any evidence for the use of the seeds of ''A. nervosa'' as a traditional entheogen in its native India,
Christian Rätsch Christian Rätsch (20 April 1957 – 17 September 2022) was a German anthropologist and writer on topics like ethnopharmacology, psychoactive plants and animals. Life Rätsch was born in 1957 in a Bohemian community in Hamburg, Germany. His fat ...
does describe some interesting traditional uses of the
root In vascular plants, the roots are the organs of a plant that are modified to provide anchorage for the plant and take in water and nutrients into the plant body, which allows plants to grow taller and faster. They are most often below the su ...
of the plant in
Ayurveda Ayurveda () is an alternative medicine system with historical roots in the Indian subcontinent. The theory and practice of Ayurveda is pseudoscientific. Ayurveda is heavily practiced in India and Nepal, where around 80% of the population rep ...
somewhat suggestive of effects upon the CNS:
The root is regarded as a tonic for the nerves and brain and is ingested as a rejuvenation tonic and
aphrodisiac An aphrodisiac is a substance that increases sexual desire, sexual attraction, sexual pleasure, or sexual behavior. Substances range from a variety of plants, spices, foods, and synthetic chemicals. Natural aphrodisiacs like cannabis or cocai ...
to increase
intelligence Intelligence has been defined in many ways: the capacity for abstraction, logic, understanding, self-awareness, learning, emotional knowledge, reasoning, planning, creativity, critical thinking, and problem-solving. More generally, it can ...
.
Other traditional uses are in the treatment of gonorrhea, strangury, chronic ulcers, diabetes, anemia, and cerebral disorders. The plant is also used as appetizer, brain tonic, cardiotonic, and aphrodisiac. It possesses anti-inflammatory, immunomodulatory, antibacterial, antiviral, and antifungal activities


References


External links


PLANTS database entry
* {{Taxonbar, from=Q383947 nervosa Decorative fruits and seeds Entheogens Flora of the Indian subcontinent Herbal and fungal hallucinogens Natural sources of lysergamides Medicinal plants of Asia Soma (drink) Plants described in 1837 Taxa named by Wenceslas Bojer Taxa named by Nicolaas Laurens Burman