Hamycin is a pair

polyene antimycotic Polyene antimycotics, sometimes referred to as polyene antibiotics, are a class of antimicrobial polyene compounds that target fungi. These polyene antimycotics are typically obtained from some species of '' Streptomyces'' bacteria. Previously, po ...

organic compound In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. T ...

s described in

India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...

. It is a heptaene antifungal compound rather similar in

chemical structure A chemical structure determination includes a chemist's specifying the molecular geometry and, when feasible and necessary, the electronic structure of the target molecule or other solid. Molecular geometry refers to the spatial arrangement of ...

amphotericin B Amphotericin B is an antifungal medication used for serious mycosis, fungal infections and leishmaniasis. The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candida infections, candidiasis, coccidioidomy ...

except that it has an additional

aromatic In chemistry, aromaticity is a chemical property of cyclic ( ring-shaped), ''typically'' planar (flat) molecular structures with pi bonds in resonance (those containing delocalized electrons) that gives increased stability compared to satur ...

group A group is a number of persons or things that are located, gathered, or classed together. Groups of people * Cultural group, a group whose members share the same cultural identity * Ethnic group, a group whose members share the same ethnic ide ...

bonded to the molecule. When pure, hamycin is a yellow, powdered

solid Solid is one of the four fundamental states of matter (the others being liquid, gas, and plasma). The molecules in a solid are closely packed together and contain the least amount of kinetic energy. A solid is characterized by structural ...

. There are two versions of hamycin with very similar

s: hamycin A and hamycin B. __TOC__

Sources

Hamycin is obtained from a strain of streptomyces bacteria growing in soil i.e., ''Streptomyces pimprina''. This compound is being produced in India by

Hindustan Antibiotics Limited Hindustan Antibiotics Limited (HAL),is an Indian Public Sector Undertakings in India, central public sector undertaking under the ownership of Ministry of Chemicals and Fertilizers, Government of India. It is based in Pune, India. It is the fir ...

, located at Pimpri, Pune, Maharashtra, India. It is similar to nystatin and it is more water-soluble.

Uses

It is useful as an antifungal antibiotic drug for

topical A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes ...

as well as systemic

mycoses Fungal infection, also known as mycosis, is disease caused by fungi. Different types are traditionally divided according to the part of the body affected; superficial, subcutaneous, and systemic. Superficial fungal infections include common ti ...

References

Antifungals Polyenes {{antimicrobial-stub