Glyceollin III is a
glyceollin
Glyceollins are a family of prenylated pterocarpans found in ineffective types of nodule in soybean in response to symbiotic infection.
It possesses two chiral centers and can be asymmetrically synthesized chemically at a gram level scale.
Mol ...
, a type of
pterocarpan
Pterocarpans are derivatives of isoflavonoids found in the family Fabaceae. It is a group of compounds which can be described as benzo-pyrano-furano-benzenes (i.e. 6''H''- enzofuro ,2-chromene skeleton) which can be formed by coupling of the B rin ...
, found in the soybean (''
Glycine max
Glycine (symbol Gly or G; ) is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid (carbamic acid is unstable), with the chemical formula NH2‐ CH2‐ COOH. Glycine is one of the proteinogeni ...
''). It has an
antiestrogenic
Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. They act by blocking the estrogen receptor (ER) and/or inh ...
effect. In soil, it has an
antifungal
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as crypto ...
activity against ''
Aspergillus sojae
''Aspergillus sojae'' is a species of fungus in the genus ''Aspergillus''.
In Japan, it is used to make the ferment ( ''kōji'') of soy sauce, miso, mirin, and other lacto-fermented condiments such as ''tsukemono''. Soy sauce condiment is produ ...
''.
[Antifungal Activity of Glyceollins Isolated from Soybean Elicited with Aspergillus sojae. Hyo Jung Kim, Hwa-Jin Suh, Choong Hwan Lee, Jeong Hwan Kim, Sun Chul Kang, Sunmin Park and Jong-Sang Kim, J. Agric. Food Chem., 2010, 58 (17), pp. 9483–9487, ]
References
Antiestrogens
Pterocarpans
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