The frontal nerve is the largest branch of the

ophthalmic nerve The ophthalmic nerve (V1) is a sensory nerve of the face. It is one of three divisions of the trigeminal nerve (CN V). It has three branches that provide sensory innervation to the eye, the skin of the upper face, and the skin of the anterior sc ...

(V₁), itself a branch of the

trigeminal nerve In neuroanatomy, the trigeminal nerve ( lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chewin ...

(CN V). It supplies sensation to the skin of the forehead, the

mucosa A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It is ...

of the

frontal sinus The frontal sinuses are one of the four pairs of paranasal sinuses that are situated behind the brow ridges. Sinuses are mucosa-lined airspaces within the bones of the face and skull. Each opens into the anterior part of the corresponding middle ...

, and the skin of the

upper eyelid An eyelid is a thin fold of skin that covers and protects an eye. The levator palpebrae superioris muscle retracts the eyelid, exposing the cornea to the outside, giving vision. This can be either voluntarily or involuntarily. The human eyel ...

. It may be affected by

schwannoma A schwannoma (or neurilemmoma) is a usually benign nerve sheath tumor composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral nerves. Schwannomas are homogeneous tumors, consisting only of Schwann cells ...

Structure

The frontal nerve is a branch of the ophthalmic nerve (V₁), itself a branch of the

(CN V). The frontal nerve branches immediately before entering the superior orbital fissure. In then travels superolateral to the

annulus of Zinn The common tendinous ring, also known as the annulus of Zinn, or annular tendon, is a ring of fibrous tissue surrounding the optic nerve at its entrance at the apex of the orbit. It is the common origin of the four recti muscles of the group of ex ...

between the

lacrimal nerve The lacrimal nerve is the smallest branch of the ophthalmic nerve (V1), itself a branch of the trigeminal nerve (CN V). The other branches of the ophthalmic nerve are the frontal nerve and nasociliary nerve. Structure The lacrimal nerve branche ...

and

inferior ophthalmic vein The inferior ophthalmic vein is a vein of the orbit that - together with the superior ophthalmic vein - represents the principal drainage system of the orbit. It begins from a venous network in the front of the orbit, then passes backwards throu ...

. After entering the orbit it travels anteriorly between the roof periosteum and the

levator palpebrae superioris The levator palpebrae superioris ( la, elevating muscle of upper eyelid) is the muscle in the orbit that elevates the upper eyelid. Structure The levator palpebrae superioris originates from inferior surface of the lesser wing of the sphenoid bo ...

. Midway between the apex and base of the orbit it divides into two branches, the

supratrochlear nerve The supratrochlear nerve is a branch of the frontal nerve, itself a branch of the ophthalmic nerve (CN V1) from the trigeminal nerve (CN V). It provides sensory innervation to the skin of the forehead and the upper eyelid. Structure The supra ...

and supraorbital nerve.

Functions

The two branches of the frontal nerve provide sensory innervation to the skin of the forehead, mucosa of the

(an air sinus), and the skin of the

Clinical significance

The frontal nerve may rarely be affected by

, a

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...

affecting its

myelin sheath Myelin is a lipid-rich material that surrounds nerve cell axons (the nervous system's "wires") to insulate them and increase the rate at which electrical impulses (called action potentials) are passed along the axon. The myelinated axon can be l ...

. This may be between the superior orbital fissure and the

supraorbital foramen The supraorbital foramen, is a bony elongated opening located above the orbit (eye socket) and under the forehead. It is part of the frontal bone of the skull. The supraorbital foramen lies directly under the eyebrow. In some people this foramen i ...

or supraorbital notch. It may cause damage to the adjacent orbital part of the

frontal bone The frontal bone is a bone in the human skull. The bone consists of two portions.''Gray's Anatomy'' (1918) These are the vertically oriented squamous part, and the horizontally oriented orbital part, making up the bony part of the forehead, par ...

. A CT scan or

magnetic resonance imaging Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio wave ...

may be used to identify the extent of the cancer. A

biopsy A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist. The process involves extraction of sample cells or tissues for examination to determine the presence or extent of a diseas ...

may be taken to confirm a diagnosis. Surgery may be used to remove the schwannoma.

Additional images

File:Gray777.png, Nerves of the orbit. The frontal nerve is visible branching from the ophthalmic nerve. File:Slide5abab.JPG, Superior view of a dissection of the orbit. The frontal nerve is visible branching into the supratrochlear and supraorbital nerves. File:Slide4ior.JPG, Superior view of a dissection of the orbit. An instrument is inserted between the frontal nerve and the levator palpebrae superioris.

References

{{Authority control Ophthalmic nerve