''Morbillivirus'' is a genus of viruses in the order '' Mononegavirales'', in the family '' Paramyxoviridae''. Humans, dogs, cats, cattle, seals, and cetaceans serve as natural hosts. This genus includes seven species. Diseases in humans associated with viruses classified in this genus include

measles Measles is a highly contagious infectious disease caused by measles virus. Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days. Initial symptoms typically include fever, often greater than , cough, ...

; in animals, they include acute febrile respiratory tract infection. In 2013, a wave of increased death among the Common bottlenose dolphin population was attributed to morbillivirus.

Genus

Structure

Morbillivirions are enveloped, with spherical geometries. Their diameter is around 150 nm. Genomes are linear, around 15-16 kb in length. The genome codes for eight proteins. Morbillivirus genomes

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaching to host cell. Replication follows the negative-stranded RNA virus replication model. Negative-stranded RNA virus transcription, using

polymerase stuttering Polymerase stuttering is the process by which a polymerase transcribes a nucleotide several times without progressing further on the mRNA chain. It is often used in addition of poly A tails or capping mRNA chains by less complex organisms such as ...

, through co-transcriptional RNA editing is the method of transcription. Translation takes place by leaky scanning. The virus exits the host cell by budding. Humans, cattle, dogs, cats, and cetaceans serve as the natural hosts. Transmission routes are respiratory.

References

External links

ICTV Report: ''Paramyxoviridae''

Virus Pathogen Database and Analysis Resource (ViPR): Paramyxoviridae
{{Authority control Morbilliviruses Virus genera