HOME
The Info List - Echinacea


--- Advertisement ---



Brauneria Necker ex T.C.Porter & Britton Helichroa Raf.

Echinacea
Echinacea
/ˌɛkɪˈneɪʃiə/[1] is a genus, or group of herbaceous flowering plants in the daisy family. The Echinacea
Echinacea
genus has nine species, which are commonly called coneflowers. They are found only in eastern and central North America, where they grow in moist to dry prairies and open wooded areas. They have large, showy heads of composite flowers, blooming from early to late summer. The generic name is derived from the Greek word ἐχῖνος (ekhinos), meaning "hedgehog," due to the spiny central disk. These flowering plants and their parts have different uses. Some species are cultivated in gardens for their showy flowers. Echinacea purpurea
Echinacea purpurea
is used in folk medicine.[2] Two of the species, E. tennesseensis and E. laevigata, are listed in the United States
United States
as endangered species.[3]

Contents

1 Description 2 Species 3 Research

3.1 Common cold 3.2 Cancer

4 Side effects

4.1 Children under 12 years old 4.2 Pregnancy 4.3 Lactation 4.4 General precaution

5 Other uses 6 History 7 See also 8 References 9 Further reading 10 External links

Description[edit]

The spiny center of the head showing the paleae, from which the name derives

A bee on an Echinacea paradoxa
Echinacea paradoxa
head (inflorescence)

A bee on an Echinacea purpurea
Echinacea purpurea
head

Echinacea
Echinacea
species are herbaceous, drought-tolerant perennial plants growing up to 140 cm or 4 feet,[4] in height. They grow from taproots, except E. purpurea, which grows from a short caudex with fibrous roots. They have erect stems that in most species are unbranched. Both the basal and cauline (stem) leaves are arranged alternately. The leaves are normally hairy with a rough texture, having uniseriate trichomes (1–4 rings of cells) but sometimes they lack hairs. The basal leaves and the lower stem leaves have petioles, and as the leaves progress up the stem the petioles often decrease in length. The leaf blades in different species may have one, three or five nerves. Some species have linear to lanceolate leaves, and others have elliptic- to ovate-shaped leaves; often the leaves decrease in size as they progress up the stems. Leaf
Leaf
bases gradually increase in width away from the petioles or the bases are rounded to heart shaped. Most species have leaf margins that are entire, but sometimes they are dentate or serrate. The flowers are collected together into single rounded heads at the ends of long peduncles. The inflorescences have crateriform to hemispheric shaped involucres which are 12–40 mm wide. The phyllaries, or bracts below the flower head, are persistent and number 15–50. The phyllaries are produced in a 2–4 series. The receptacles are hemispheric to conic. The paleae (chaffs on the receptacles of many Asteraceae) have orange to reddish purple ends, and are longer than the disc corollas. The paleae bases partially surrounding the cypselae, and are keeled with the apices abruptly constricted to awn-like tips. The ray florets number 8–21 and the corollas are dark purple to pale pink, white, or yellow. The tubes of the corolla are hairless or sparsely hairy, and the laminae are spreading, reflexed, or drooping in habit and linear to elliptic or obovate in shape. The abaxial faces of the laminae are glabrous or moderately hairy. The flower heads have typically 200–300 fertile, bisexual disc florets but some have more. The corollas are pinkish, greenish, reddish-purple or yellow and have tubes shorter than the throats. The pollen is normally yellow in most species, but usually white in E. pallida. The three or four-angled fruits (cypselae), are tan or bicolored with a dark brown band distally. The pappi are persistent and variously crown-shaped with 0 to 4 or more prominent teeth. x = 11.[5] Like all members of the sunflower family, the flowering structure is a composite inflorescence, with rose-colored (rarely yellow or white) florets arranged in a prominent, somewhat cone-shaped head – "cone-shaped" because the petals of the outer ray florets tend to point downward (are reflexed) once the flower head opens, thus forming a cone. Plants are generally long lived, with distinctive flowers. The common name "cone flower" comes from the characteristic center "cone" at the center of the flower head. The generic name Echinacea
Echinacea
is rooted in the Greek word ἐχῖνος (echinos), meaning hedgehog,[6] it references the spiky appearance and feel of the flower heads. Species[edit] DNA analysis
DNA analysis
is applied to determine the number of Echinacea
Echinacea
species, allowing clear distinctions among species based on chemical differences in root metabolites.[7] The research concluded that of the 40 genetically diverse populations of Echinacea
Echinacea
studied, there were nine distinct species. Species:[8]

Echinacea angustifolia
Echinacea angustifolia
– Narrow-leaf coneflower Echinacea atrorubens
Echinacea atrorubens
– Topeka purple coneflower Echinacea laevigata
Echinacea laevigata
– Smooth coneflower, smooth purple coneflower Echinacea pallida
Echinacea pallida
– Pale purple coneflower Echinacea paradoxa
Echinacea paradoxa
– Yellow coneflower, Bush's purple coneflower Echinacea purpurea
Echinacea purpurea
– Purple coneflower, eastern purple coneflower Echinacea sanguinea – Sanguine purple coneflower Echinacea serotina – Narrow-leaved purple coneflower Echinacea simulata
Echinacea simulata
– Wavyleaf purple coneflower Echinacea tennesseensis
Echinacea tennesseensis
– Tennessee coneflower

Research[edit] Echinacea
Echinacea
products vary widely in composition.[9] They contain different species (E. purpurea, E. angustifolia, E. pallida), different plant segments (roots, flowers, extracts), different preparations (extracts and expressed juice), and different chemical compositions which complicate understanding of a potential effect.[10][11] Well-controlled clinical trials are limited and low in quality.[11][12] Although there are multiple scientific reviews and meta-analyses published on the supposed immunological effects of Echinacea, significant variability of products used among studies has limited conclusions about effects and safety, consequently leading to non-approval by regulatory authorities like the United States
United States
Food and Drug
Drug
Administration of any health benefit or anti-disease activity.[2][11] Common cold[edit] While one 2014 systematic review found that Echinacea
Echinacea
products are not effective to treat or prevent the common cold,[12] a 2016 meta-analysis found tentative evidence that use of Echinacea
Echinacea
extracts reduced the risk of repeated respiratory infections.[13] A 2015 monograph by the European Medicines Agency
European Medicines Agency
stated that oral consumption of "expressed juice" or dried expressed juice of Echinacea could prevent or reduce symptoms of a common cold at its onset.[14] As of 2017, the benefit, if any, appears to be small and thus of little utility.[15] Cancer[edit] According to Cancer Research UK: "There is no scientific evidence to show that echinacea can help treat, prevent or cure cancer in any way. Some therapists have claimed that echinacea can help relieve side effects from cancer treatments such as chemotherapy and radiotherapy, but this has not been proven either."[16] Side effects[edit] When taken by mouth, Echinacea
Echinacea
does not usually cause side effects,[2] but may have undesirable interactions with various drugs prescribed for diseases, such as heart disease, bleeding, and autoimmune diseases, such as rheumatoid arthritis, lupus, or psoriasis.[17][18] Although there are no specific case reports of drug interactions with Echinacea,[19] safety about taking Echinacea
Echinacea
supplements is not well-understood, with possibilities that it may cause side effects, such as nausea, stomach upset or diarrhea, and that it may have adverse reactions with other medications.[17] One of the most extensive and systematic studies to review the safety of Echinacea products concluded that overall, "adverse events are rare, mild and reversible," with the most common symptoms being "gastrointestinal and skin-related."[20] Such side effects include nausea, abdominal pain, diarrhea, itch, and rash.[18] Echinacea
Echinacea
has also been linked to allergic reactions, including asthma, shortness of breath, and one case of anaphylaxis.[20][21][22] Muscle and joint pain has been associated with Echinacea, but it may have been caused by cold or flu symptoms for which the Echinacea
Echinacea
products were administered.[20] There are isolated case reports of rare and idiosyncratic reactions including thrombocytopenic purpura, leucopenia, hepatitis, kidney failure, and atrial fibrillation, although it is not clear that these were due to Echinacea
Echinacea
itself.[17] Up to 58 drugs or supplements may interact with Echinacea.[18] As a matter of manufacturing safety, one investigation by an independent-consumer testing laboratory found that five of eleven selected retail Echinacea
Echinacea
products failed quality testing. Four of the failing products contained levels of phenols below the potency level stated on the labels. One failing product was contaminated with lead.[23] Children under 12 years old[edit] The European Herbal Medicinal Products Committee (HMPC) and the UK Herbal Medicines Advisory Committee (HMAC) recommended against the use of Echinacea-containing products in children under the age of 12. Manufacturers re-labelled all oral Echinacea
Echinacea
products that had product licenses for children with a warning that they should not be given to children under 12 as a precautionary measure.[24] Pregnancy[edit] Although research has not found increased risk of birth defects associated with use of Echinacea
Echinacea
during the first trimester, it is recommended that pregnant women should avoid Echinacea
Echinacea
products until stronger safety supporting evidence becomes available.[17] Lactation[edit] It is recommended that women breastfeeding should use caution with Echinacea
Echinacea
products due to insufficient safety information available.[17] General precaution[edit] The U.S. Food and Drug Administration
Food and Drug Administration
recommends precaution about using dietary supplements because some products may not be risk free under certain circumstances or may interact with prescription and over-the-counter medicines.[25] As with any herbal preparation, individual doses of Echinacea
Echinacea
may vary significantly in chemical composition.[2] Inconsistent process control in manufactured echinacea products may involve poor inter- and intra-batch homogeneity, species or plant part differences, variable extraction methods, and contamination or adulteration with other products, leading to potential for substantial product variability.[12][23] Other uses[edit] Some species of Echinacea, notably E. purpurea, E. angustifolia, and E. pallida, are grown as ornamental plants in gardens.[26] Many cultivars exist, and many of them are asexually propagated to keep them true to type. Echinacea
Echinacea
extracts inhibited growth of three species of trypanosomatids: Leishmania donovani, Leishmania major, and Trypanosoma brucei.[27] History[edit] Echinacea angustifolia
Echinacea angustifolia
was widely used by the North American Plains Indians for its supposed medicinal qualities.[28] According to Wallace Sampson, its modern use for the common cold began when a Swiss herbal supplement maker was "erroneously told" that Echinacea
Echinacea
was used for cold prevention by Native American tribes who lived in the area of South Dakota.[29] Although Native American tribes did not use Echinacea
Echinacea
for the common cold, some Plains tribes did use echinacea for cold symptoms. The Kiowa
Kiowa
used it for coughs and sore throats, the Cheyenne
Cheyenne
for sore throats, the Pawnee for headaches, and many tribes including the Lakotah used it as a pain medication.[30] See also[edit]

List of ineffective cancer treatments

References[edit]

^ Sunset Western Garden Book, 1995:606–607 ^ a b c d "Echinacea: NCCIH Herbs at a Glance". National Center for Complementary and Integrative Health, US National Institutes of Health. September 2015.  ^ Kelly, Kindscher. "The Conservation Status of Echinacea
Echinacea
Species" (PDF). USDA. Retrieved 29 October 2014.  ^ 32 ^ " Echinacea
Echinacea
in Flora of North America
North America
@". Efloras.org. Retrieved 2010-02-01.  ^ Plowden, Celeste. A manual of plant names. London, Allen and Unwin, 1972. p. 47. ISBN 0-04-580008-1.  ^ Perry, Ann. 2010. Exploring Echinacea’s Enigmatic Origins. United States Department of Agriculture, Agricultural Research Service ^ The Plant
Plant
List search for Echinacea ^ "The Common Cold and Complementary Health Approaches: What the Science Says". U.S. Department of Health and Human Services. Retrieved 1 November 2014.  ^ Barnes J, Anderson LA, Gibbons S, Phillipson JD (2005). "Echinacea species ( Echinacea angustifolia
Echinacea angustifolia
(DC.) Hell., Echinacea pallida
Echinacea pallida
(Nutt.) Nutt., Echinacea purpurea
Echinacea purpurea
(L.) Moench): a review of their chemistry, pharmacology and clinical properties". J Pharm Pharmacol. 57 (8): 929–54. doi:10.1211/0022357056127. PMID 16102249.  ^ a b c Hart A, Dey P (2009). " Echinacea
Echinacea
for prevention of the common cold: an illustrative overview of how information from different systematic reviews is summarised on the internet". Preventive Medicine. 49 (2–3): 78–82. doi:10.1016/j.ypmed.2009.04.006. PMID 19389422.  ^ a b c Karsch-Völk M, Barrett B, Kiefer D, Bauer R, Ardjomand-Woelkart K, Linde K (2014). " Echinacea
Echinacea
for preventing and treating the common cold". Cochrane Database Syst Rev (Systematic review). 2 (2): CD000530. doi:10.1002/14651858.CD000530.pub3. PMC 4068831 . PMID 24554461.  ^ Schapowal, A; Klein, P; Johnston, S. L (2015). " Echinacea
Echinacea
reduces the risk of recurrent respiratory tract infections and complications: A meta-analysis of randomized controlled trials". Advances in Therapy. 32 (3): 187–200. doi:10.1007/s12325-015-0194-4. PMID 25784510.  ^ "European Union herbal monograph on Echinacea purpurea
Echinacea purpurea
(L.) Moench, herba recens" (PDF). Committee on Herbal Medicinal Products, European Medicines Agency. 24 November 2015. Retrieved 16 March 2018.  ^ "The Common Cold and Complementary Health Approaches". NCCIH. August 2017. Retrieved 3 November 2017.  ^ "Echinacea". Cancer Research UK. Retrieved October 22, 2012.  ^ a b c d e " Echinacea
Echinacea
( Echinacea angustifolia
Echinacea angustifolia
DC, Echinacea
Echinacea
pallida, Echinacea
Echinacea
purpurea): Safety". Mayo Clinic. Retrieved 2011-09-05.  ^ a b c "Echinacea". Drugs.com. 2017. Retrieved 2 November 2017.  ^ Izzo AA, Ernst E (2009). "Interactions between herbal medicines and prescribed drugs: an updated systematic review". Drugs. 69 (13): 1777–98. doi:10.2165/11317010-000000000-00000. PMID 19719333.  ^ a b c Huntley AL, Thompson Coon J, Ernst E (2005). "The safety of herbal medicinal products derived from Echinacea
Echinacea
species: a systematic review". Drug
Drug
Saf. 28 (5): 387–400. doi:10.2165/00002018-200528050-00003. ISSN 0114-5916. PMID 15853441.  ^ Mullins RJ. Echinacea-associated anaphylaxis. Med J Aust 1998;168: 170-171 ^ Ang-Lee MK, Moss J, Yuan CS (July 2001). "Herbal medicines and perioperative care". JAMA. 286 (2): 208–16. doi:10.1001/jama.286.2.208. PMID 11448284.  ^ a b "Product Review: Echinacea". ConsumerLab.com, LLC. 18 March 2004. Retrieved 2 August 2007.  ^ "Press release: Echinacea
Echinacea
herbal products should not be used in children under 12 years old". MHRA.  ^ "Tips for Dietary Supplement Users". U.S. Food and Drug Administration. Retrieved 1 November 2014.  ^ "A Comprehensive Echinacea
Echinacea
Germplasm Collection Located at the North Central Regional Plant
Plant
Introduction Station", USDA ^ Canlas J, Hudson JB, Sharma M, Nandan D.," Echinacea
Echinacea
and trypanasomatid parasite interactions: Growth-inhibitory and anti-inflammatory effects of Echinacea". Pharm Biol. 2010 Sep;48(9):1047-52 ^ Wishart, David J. (2007). Encyclopedia of the Great Plains Indians. U of Nebraska Press. p. 156. ISBN 978-0-8032-9862-0.  ^ Study: Echinacea
Echinacea
Cuts Colds by Half WebMD Health News, June 26, 2007 ^ Moerman, Daniel E. (1998). Native American Ethnobotany. Timber Press. p. 205. ISBN 978-0-88192-453-4. 

Further reading[edit]

Mowrey, Daniel (1998). Echinacea. McGraw-Hill Professional. ISBN 978-0-87983-610-8. 

External links[edit]

Wikimedia Commons has media related to Echinacea.

Wikispecies
Wikispecies
has information related to Echinacea

Echinacea
Echinacea
at Curlie (based on DMOZ)

Taxon identifiers

Wd: Q1642983 EoL: 59379 EPPO: 1ECEG FNA: 111203 FoC: 111203 GBIF: 3150914 GRIN: 4094 IPNI: 8725-1 ITIS: 37275 NCBI: 53747 PLANTS: ECHIN Tropicos: 400

.

Time at 25413640.066667, Busy percent: 30
***************** NOT Too Busy at 25413640.066667 3../logs/periodic-service_log.txt
1440 = task['interval'];
25414985.983333 = task['next-exec'];
25413545.983333 = task['last-exec'];
daily-work.php = task['exec'];
25413640.066667 Time.

10080 = task['interval'];
25423626 = task['next-exec'];
25413546 = task['last-exec'];
weekly-work.php = task['exec'];
25413640.066667 Time.

1440 = task['interval'];
25414986 = task['next-exec'];
25413546 = task['last-exec'];
PeriodicStats.php = task['exec'];
25413640.066667 Time.

1440 = task['interval'];
25414986 = task['next-exec'];
25413546 = task['last-exec'];
PeriodicBuild.php = task['exec'];
25413640.066667 Time.

1440 = task['interval'];
25414986.016667 = task['next-exec'];
25413546.016667 = task['last-exec'];
cleanup.php = task['exec'];
25413640.066667 Time.

1440 = task['interval'];
25414986.033333 = task['next-exec'];
25413546.033333 = task['last-exec'];
build-sitemap-xml.php = task['exec'];
25413640.066667 Time.