Christopher Evans (businessman)
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Sir Christopher Thomas Evans (born 29 November 1957) is a Welsh professor, scientist and
biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used ...
entrepreneur. Evans is known for founding and co-founding numerous successful
biotech Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
companies in the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the European mainland, continental mainland. It comprises England, Scotlan ...
. Since the 1980s, Evans has launched and supported more than 50 companies in the
biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used ...
sector, including 20 listed on six different stock markets. Many have specialised in their goal of creating unique products and medicines as well as
clinical trial Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, diet ...
s. These include an S-Ketoprofen anti-inflammatory pharmaceutical, single isomer chiral
synthon In retrosynthetic analysis, a synthon is a hypothetical unit within a target molecule that represents a potential starting reagent in the retroactive synthesis of that target molecule. The term was coined in 1967 by E. J. Corey. He noted in 1 ...
s for use in new anti-viral drugs, a single-isomer
levobupivacaine Levobupivacaine (International Nonproprietary Name, rINN) is a local anaesthetic drug belonging to the amino amide group. It is the ''S''-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AbbVie under the trade nam ...
for local anaesthesia, the pre-eminent rapid bioluminescent test for bacterial contamination, numerous enzymes and proteins for use in clinical diagnostic tests as well as stem cell therapies, immunotherapeutics, oncology drugs and respiratory devices.


Early life

Evans was born in 1957, in
Port Talbot Port Talbot (, ) is a town and community in the county borough of Neath Port Talbot, Wales, situated on the east side of Swansea Bay, approximately from Swansea. The Port Talbot Steelworks covers a large area of land which dominates the south ...
, to Cyril and Jeanette (Cottey) Evans. He attended St Joseph's School in Port Talbot before studying microbiology at
Imperial College London Imperial College London (legally Imperial College of Science, Technology and Medicine) is a public research university in London, United Kingdom. Its history began with Prince Albert, consort of Queen Victoria, who developed his vision for a cu ...
. He then obtained a PhD from the
University of Hull , mottoeng = Bearing the Torch f learning, established = 1927 – University College Hull1954 – university status , type = Public , endowment = £18.8 million (2016) , budget = £190 million ...
and
Porton Down Porton Down is a science park in Wiltshire, England, just northeast of the village of Porton, near Salisbury. It is home to two British government facilities: a site of the Ministry of Defence's Defence Science and Technology Laboratory (Dstl ...
, followed by a research fellowship at the
University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...
.


Career

Evans' first company, Enzymatix, was one of the earliest
biotech Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
companies in Europe. Its early work involve the use of cabbages and eggs to mass-produce
phospholipids Phospholipids, are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids, joined by an alcohol residue (usually a glycerol molecule). Marine phospholipids t ...
which were used in surfactants to help premature babies breathe. Evans was a co-founder of the biotech business
Chiroscience Chiroscience Group Plc was a British-based biotech company, founded by Christopher Evans. The company was taken over by Celltech in 1999, which was acquired in 2004 by UCB. History Chiroscience was born from the demise of the company Enzymati ...
, which was founded in 1991. The company made a number of breakthroughs in the early 1990s. It developed an anesthetic known as Chirocaine, and discovered
Romosozumab Romosozumab, sold under the brand name Evenity, is a medication used to treat osteoporosis. It has been found to decrease the risk of fractures of the spine. Common side effect include headache, joint pain, and pain at the site of injection. ...
, which was later acquired by Celltech. In 1992, Evans was the founder of Celsis, which was based in
Cambridge Cambridge ( ) is a College town, university city and the county town in Cambridgeshire, England. It is located on the River Cam approximately north of London. As of the 2021 United Kingdom census, the population of Cambridge was 145,700. Cam ...
, UK. It specialised in contamination detectors, which included a revolutionary test to detect
E.coli ''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Esche ...
in water.
Chiroscience Chiroscience Group Plc was a British-based biotech company, founded by Christopher Evans. The company was taken over by Celltech in 1999, which was acquired in 2004 by UCB. History Chiroscience was born from the demise of the company Enzymati ...
became one of the UK's first
biotech Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
companies to go public in 1994, when it filed for its
initial public offering An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investme ...
. Evans remained at the business for another couple of years and left prior to its merger with
Celltech Celltech Group plc was a leading British-based biotechnology business based in Slough. It was listed on the London Stock Exchange and was a constituent of the FTSE 100 Index. History Celltech was founded by Gerard Fairtlough in 1980 with fina ...
in 1999. Evans founded a number of ventures under the Merlin group. During the 1990s, Merlin focused on partnering with entrepreneurs to create new businesses, in a similar way to how
seed funding Seed money, sometimes known as seed funding or seed capital, is a form of securities offering in which an investor invests capital in a startup company in exchange for an equity stake or convertible note stake in the company. The term ''seed'' su ...
is now used. Early investments were made in over 20 life science based companies. A £2.5 million investment was made in
Cyclacel Cyclacel Pharmaceuticals Inc. is a biotechnology firm based in Berkeley Heights, New Jersey Berkeley Heights is a township in Union County, New Jersey, United States. A commuter town in northern- central New Jersey, the township is nestled wit ...
in 1997. In 1994, founded Toad, a vehicle technology company specialising in car security devices which went to be a publicly listed company. In 1997, Evans co-founded ReNeuron, a stem cell research company. The company's research focused on treatments to reverse the effects of neurological diseases. In 1998, Evans founded Biovex, a company which specialised in the development of a genetically modified herpes virus which kills off cancer cells. The company was ultimately sold to Amgen in 2011 for $1 billion. Later that year, Lord
David Puttnam David Terence Puttnam, Baron Puttnam, CBE, HonFRSA, HonFRPS, MRIA (born 25 February 1941) is a British film producer, educator, environmentalist and former member of the House of Lords. His productions include ''Chariots of Fire'', which wo ...
assembled a team of eight trustees for the National Endowment for Science, Technology and the Arts, which included Evans. This later became known as
Nesta Nesta (formerly NESTA, National Endowment for Science, Technology and the Arts) is an innovation foundation based in the UK. The organisation acts through a combination of programmes, investment, policy and research, and the formation of part ...
. It was awarded £200 million by the British government in the 1998 budget. In 2000, ReNeuron was listed on the
Alternative Investment Market AIM (formerly the Alternative Investment Market) is a sub-market of the London Stock Exchange that was launched on 19 June 1995 as a replacement to the previous Unlisted Securities Market (USM) that had been in operation since 1980. It allows ...
in a £60 million listing. In 2004, Vectura a respiratory drug company founded by Evans was listed the Alternative Investment Market. In 2021, The Philip Morris Group made a successful bid of £1billion for the company. Arakis Limited, one of the companies developed by Evans was sold to Sosei Co. Ltd for £106.5 million in 2005. Evans’ Excalibur Group sold Piramed, which developed treatments for cancer and autoimmune diseases to Roche in 2008 for £$175 million dollars. In 2013, Evans founded Arthurian Life Sciences, which aimed to bring
biotech Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
investment into the Welsh economy. A year later, it worked with the Welsh Government to create and build the Wales Life Sciences Investment Fund, a £100 million 50/50 joint venture life sciences investment fund created to attract business to Wales. The fund has invested in and provided grants to ReNeuron, in which Evans also invested. In 2015, Evans led the investment funding for Proton Partners International to create the UK’s first network of centres offering
proton beam A charged particle beam is a spatially localized group of electrically charged particles that have approximately the same position, kinetic energy (resulting in the same velocity), and direction. The kinetic energies of the particles are much ...
therapy, a specialised form of radiotherapy. Proton Partners later became Rutherford Health and Evans remains a non-executive director. In 2016, Evans founded and became deputy chairman of Arix Bioscience, a health and life sciences company investing in medical innovation. The company was listed on the
London Stock Exchange London Stock Exchange (LSE) is a stock exchange in the City of London, England, United Kingdom. , the total market value of all companies trading on LSE was £3.9 trillion. Its current premises are situated in Paternoster Square close to St P ...
with a market cap of £200m in 2017. In 2017, founded and became chairman of Ellipses Pharma, a company specialising in the development of new cancer drugs. In 2019, Evans created Excalibur Healthcare Services to specialise in international medical supplies, clinical research and development, diagnostics and testing. The company was formally incorporated in January 2020. In April 2020, Excalibur was at the forefront of the first phase of a
clinical trial Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, diet ...
which could help diabetics that contract
COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Wuhan, China, in December 2019. The disease quickly ...
. The trial was arranged and structured by Evans. The second phase of the trial received £10 million in funding in August 2020.


Awards

Evans holds 10 honorary professorships, 6 fellowships and a doctorate in sciences. He has been the author of more than 100 scientific publications and patents. In 1998, he became the youngest recipient of Society of Chemical Industry Centenary medal and was awarded the Henderson Memorial Medal. A year later in 1999, he received the Royal Society of Chemistry Interdisciplinary Medal. Evans has twice been the recipient of "Cambridge Businessman of the Year" in 1996 and 1998. He was awarded the OBE in 1995 and knighted in 2001. He was appointed a Honorary
Fellow A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher education ...
of the Royal Academy of Engineering in 2005. In March of that year, he was appointed by
Gordon Brown James Gordon Brown (born 20 February 1951) is a British former politician who served as Prime Minister of the United Kingdom and Leader of the Labour Party from 2007 to 2010. He previously served as Chancellor of the Exchequer in Tony B ...
to the UK Stem Cell Initiative. He made a £1 million loan to the British Labour Party during 2005, which became part of a wider police investigation into party donations, but on 19 July 2007 the UK
Crown Prosecution Service The Crown Prosecution Service (CPS) is the principal public agency for conducting criminal prosecutions in England and Wales. It is headed by the Director of Public Prosecutions. The main responsibilities of the CPS are to provide legal advi ...
announced he was cleared of any wrongdoing.


Personal life

Evans resides in the Cotswolds, and was listed in the '' Sunday Times Rich List 2020'' in 583rd place with an estimated fortune of £208 million. He has a wife and four grown children.


Philanthropy

In 2018, Evans launched the Evamore project, a musical collaboration inspired from the letters of
First World War World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
soldiers. The first release from the project, "One More Yard", was written by Evans and published in November 2018 to mark the centenary of
Armistice Day Armistice Day, later known as Remembrance Day in the Commonwealth and Veterans Day in the United States, is commemorated every year on 11 November to mark the armistice signed between the Allies of World War I and Germany at Compiègne, Fran ...
. Sinead O’Connor sang lead vocals on the track, with supporting vocals by
Imelda May Imelda Mary Higham (born Imelda Mary Clabby, 10 July 1974), professionally known as Imelda May, is an Irish singer, songwriter and multi-instrumentalist. Known primarily as a singer, she also plays the bodhrán, guitar, bass guitar and tambou ...
. Guitar was played by
Ronnie Wood Ronald David Wood (born 1 June 1947) is an English rock musician, best known as an official member of the Rolling Stones since 1975, as well as a member of Faces and the Jeff Beck Group. Wood began his career in 1964, playing guitar with a ...
, with Nick Mason playing on drums, whilst instrumentation was provided by Brian Eno and spoken word excerpts recorded by actor
Cillian Murphy Cillian Murphy (; born 25 May 1976) is an Irish actor. Originally the lead singer, guitarist, and lyricist of the rock band The Sons of Mr. Green Genes, he turned down a record deal in the late 1990s and began acting on stage and in short an ...
. Proceeds from Evamore were donated to The Cancer Awareness Trust, a charity founded by Evans which aims to build ‘useful, reliable and easily understood information’ for use by individuals who have been diagnosed with cancer. Evans founded The UK Stem Cell Foundation in 2005, a charity focused on funding stem cell research.


References


External links


Personal Profile page

Ellipses Pharma

Excalibur Health Services

The Evamore Project
{{DEFAULTSORT:Evans, Christopher 1957 births Living people People from Port Talbot Alumni of Imperial College London Alumni of the University of Hull University of Michigan alumni 20th-century Welsh businesspeople Businesspeople in the pharmaceutical industry Businesspeople awarded knighthoods Officers of the Order of the British Empire Knights Bachelor Labour Party (UK) people 21st-century Welsh businesspeople