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Chiroscience
Chiroscience Group Plc was a British-based biotech company, founded by Christopher Evans. The company was taken over by Celltech in 1999, which was acquired in 2004 by UCB. History Chiroscience was born from the demise of the company Enzymatix, which was ultimately acquired by Genzyme, when Andrew Richards joined the company and convinced Evans and Peter Keen to launch Chiros, which name was quickly revised to Chrioscience. Seed funding for the company of was provided by Schroder Ventures, Apax and 3i. Chiroscience became one of the first biotechnology Initial Public Offerings in the United Kingdom in 1994. In 1996, the company merged with the American biotech company ''Darwin Molecular Corporation'', based in Cambridge, Massachusetts, retaining Chiroscience as its name. By the time of its merger with Celltech in 1999, both Chris Evans and Peter Keen had left the company, leaving Andrew Richards as the sole remaining founder and member of the original management board. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Celltech
Celltech Group plc was a leading British-based biotechnology business based in Slough. It was listed on the London Stock Exchange and was a constituent of the FTSE 100 Index. History Celltech was founded by Gerard Fairtlough in 1980 with finance from the National Enterprise Board. Amongst the work conducted at Celltech was the cloning of the glutamine synthetase (GS) gene in CHO cells leading to the creation of a biotechnology tool still widely used to express recombinant eukaryotic proteins. In 1999 Celltech led consolidation in the UK biosciences market merging with ''Chiroscience plc'', after which it was briefly referred to as ''Celltech Chiroscience,'' and then buying ''Medeva plc''. Then in 2000 it bought ''Cistron'', a US biosciences business. It expanded into Germany in 2001 buying Thiemann, a German biosciences business, and went on to buy Oxford Glycosciences in July 2003 for £102m. Celltech was acquired by UCB, a Belgian drugmaker, in 2004. Since then it has bee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christopher Evans (businessman)
Sir Christopher Thomas Evans (born 29 November 1957) is a Welsh professor, scientist and biotechnology entrepreneur. Evans is known for founding and co-founding numerous successful biotech companies in the United Kingdom. Since the 1980s, Evans has launched and supported more than 50 companies in the biotechnology sector, including 20 listed on six different stock markets. Many have specialised in their goal of creating unique products and medicines as well as clinical trials. These include an S-Ketoprofen anti-inflammatory pharmaceutical, single isomer chiral synthons for use in new anti-viral drugs, a single-isomer levobupivacaine for local anaesthesia, the pre-eminent rapid bioluminescent test for bacterial contamination, numerous enzymes and proteins for use in clinical diagnostic tests as well as stem cell therapies, immunotherapeutics, oncology drugs and respiratory devices. Early life Evans was born in 1957, in Port Talbot, to Cyril and Jeanette (Cottey) Evans. He atte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Romosozumab
Romosozumab, sold under the brand name Evenity, is a medication used to treat osteoporosis. It has been found to decrease the risk of fractures of the spine. Common side effect include headache, joint pain, and pain at the site of injection. It may increase the risk of heart attacks, strokes, and deaths from cardiovascular disease. It is a humanized monoclonal antibody that targets sclerostin. Research shows the drug increases bone formation and decreases bone resorption in postmenopausal women with low bone density. Romosozumab was approved for medical use in Japan, the United States and the European Union in 2019. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. Medical uses Romosozumab is used for osteoporosis to decrease the risk of fractures. Two trials found that it reduced the rate of vertebral fracture. In one, there was a 73% lower risk of vertebral fracture after one year, and the benefit was maintained after a second yea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotech
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UCB (company)
UCB (Union Chimique Belge) is a multinational biopharmaceutical company headquartered in Brussels, Belgium. UCB is an international company with revenue of €4.178 billion in 2016 which focuses primarily on research and development, specifically involving medications centered on epilepsy, Parkinson's disease, and Crohn's disease. The company's efforts are focused on treatments for severe diseases treated by specialists, particularly in the fields of central nervous system (CNS) disorders (including epilepsy), inflammatory disorders (including allergy), and oncology. Every three years, the company presents the UCB Award under the patronage of the Queen Elisabeth Medical Foundation to promote neuroscience research. The winner of this award is selected by an independent scientific committee. History UCB was founded on 18 January 1928 by Emmanuel Janssen, a Belgian businessman. Initially focused on industrial chemicals (it was one of the first companies to distill ammonia fro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Schroder Ventures
Permira is a global investment firm. Founded in 1985, the firm advises funds with assets under management of €60+ billion. The Permira funds have made approximately 300 private equity investments in four key sectors: Technology, Consumer, Services and Healthcare. Permira employs over 360 people in 16 offices across North America, Europe and Asia. History Permira was founded in 1985 by Nicholas Ferguson as a number of country-specific separate businesses operating under the Schroder Ventures brand. In 1996, the United Kingdom, French, German and Italian teams joined to create Schroder Ventures Europe and in 1997, this raised its first pan-European fund. In 2001, the firm was renamed Permira. In 2002, Permira expanded into the U.S. with the opening of its New York office. In 2005, Permira launched its first Asia Pacific-based office in Japan. It later opened its Hong Kong office in 2008. In 2006, Permira raised over €10 billion in commitments for its P4 fund, which was, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apax Partners
Apax Partners LLP is a British private equity firm, headquartered in London, England. The company also operates out of six other offices in New York, Hong Kong, Mumbai, Tel Aviv, Munich and Shanghai. As of December 2017, the firm, including its various predecessors, have raised approximately $51 billion (USD) since 1981. Apax Partners is one of the oldest and largest private equity firms operating on an international basis, ranked the fifteenth largest private equity firm globally. Apax invests exclusively in certain business sectors including: telecommunications, technology, retail and consumer products, healthcare and financial and business services. Looks for a target Enterprise Value of $1,000mm - $5,000mm. Apax raises capital for its investment funds through institutional investors including corporate and public pension funds, university and college endowments, foundations and fund of funds. One of the firm's co-founders, Alan Patricof, was an early investor in Apple ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Initial Public Offering
An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investment banks, who also arrange for the shares to be listed on one or more stock exchanges. Through this process, colloquially known as ''floating'', or ''going public'', a privately held company is transformed into a public company. Initial public offerings can be used to raise new equity capital for companies, to monetize the investments of private shareholders such as company founders or private equity investors, and to enable easy trading of existing holdings or future capital raising by becoming publicly traded. After the IPO, shares are traded freely in the open market at what is known as the free float. Stock exchanges stipulate a minimum free float both in absolute terms (the total value as determined by the share price multiplied by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cambridge, Massachusetts
Cambridge ( ) is a city in Middlesex County, Massachusetts, United States. As part of the Boston metropolitan area, the cities population of the 2020 U.S. census was 118,403, making it the fourth most populous city in the state, behind Boston, Worcester, and Springfield. It is one of two de jure county seats of Middlesex County, although the county's executive government was abolished in 1997. Situated directly north of Boston, across the Charles River, it was named in honor of the University of Cambridge in England, once also an important center of the Puritan theology embraced by the town's founders. Harvard University, the Massachusetts Institute of Technology (MIT), Lesley University, and Hult International Business School are in Cambridge, as was Radcliffe College before it merged with Harvard. Kendall Square in Cambridge has been called "the most innovative square mile on the planet" owing to the high concentration of successful startups that have emerged in the vicinity ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chirocaine
Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the ''S''-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AbbVie under the trade name Chirocaine.Rossi S, editor. Australian Medicines Handbook 2006. Adelaide: Australian Medicines Handbook; 2006. Clinical use Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 percent less potent (by molarity) than racemic bupivacaine and has a longer motor block onset time. Indications Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. Contraindications Levobupivacaine is contraindicated for IV regional anaesthesia (IVRA). Adverse effects Adverse drug reactions (ADRs) are rare when it is administered correctly. Most ADRs relate to administration ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutical Industry In The United Kingdom
The pharmaceutical industry in the United Kingdom directly employs around 73,000 people and in 2007 contributed £8.4 billion to the UK's GDP and invested a total of £3.9 billion in research and development. In 2007 exports of pharmaceutical products from the UK totalled £14.6 billion, creating a trade surplus in pharmaceutical products of £4.3 billion. UK Pharmaceutical employment of 73,000 in 2017 compares to 114,000 as of 2015 in Germany, 92,000 as of 2014 in France and 723,000 in the European Union as a whole. In the United States 281,440 people work in pharmaceutical industry as of 2016. The UK is home to GlaxoSmithKline and AstraZeneca, respectively the world's fifth- and sixth-largest pharmaceutical companies measured by 2009 market share. It is also home to the multinational Hikma Pharmaceuticals. Foreign companies with a major presence in the UK pharmaceutical industry include Pfizer, Novartis, Hoffmann–La Roche and Eisai. One in five of the world's biggest-selling ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
