Adipostatin A is an
alkylresorcinol, a type of
phenolic lipid
Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids includ ...
s composed of long aliphatic chains and phenolic rings. Chemically, it is similar in structure to
urushiol
Urushiol is an oily mixture of organic compounds with allergenic properties found in plants of the family Anacardiaceae, especially '' Toxicodendron'' ''spp.'' (e.g., poison oak, Chinese lacquer tree, poison ivy, poison sumac), ''Comoclad ...
, the irritant found in
poison ivy.
Adipostatin A can be found in ''
Gingko biloba
''Ginkgo biloba'', commonly known as ginkgo or gingko ( ), also known as the maidenhair tree, is a species of tree native to China. It is the last living species in the order Ginkgoales, which first appeared over 290 million years ago. Fossils ...
'' fruits as well as in ''
Streptomyces cyaneus''. It is also found in
cashew nutshell liquid (''Anacardium occidentale''), in ''
Anacardium othonianum
''Anacardium othonianum'' is a tree native from the tropical savanna (''cerrado'') region of Brazil, whose fruit is similar to (but smaller than) that of the common cashew tree ('' A. occidentale'') of the Brazilian Northeast. It is locally kno ...
'' and in ''
Ardisia elliptica
''Ardisia elliptica'' is an evergreen tree, also known as the shoebutton ardisia, duck's eye and coralberry, native to the west coast of India, Sri Lanka, Indochina, Malaysia, Indonesia and New Guinea. It is a prolific reproducer which has made i ...
''.
It is an inhibitor of
glycerol-3-phosphate dehydrogenase
''sn''-Glycerol 3-phosphate is the organic ion with the formula HOCH2CH(OH)CH2OPO32-. It is one of three stereoisomers of the ester of dibasic phosphoric acid (HOPO32-) and glycerol. It is a component of glycerophospholipids. Equally appropriat ...
.
References
Alkylresorcinols
{{phenol-stub