Armand Trousseau
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Armand Trousseau (14 October 1801 – 23 June 1867) was a French internist. His contributions to medicine include Trousseau sign of malignancy, Trousseau sign of latent tetany, Trousseau–Lallemand bodies (an archaic synonym for
Bence Jones protein Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22–24 kDa. Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenström's macroglobuli ...
s). He is sometimes credited with the quip "use new drugs quickly, while they still work", though
Michel-Philippe Bouvart Michel-Philippe Bouvart (Chartres, 11 January 1717 – Paris, 19 January 1787) was a French medical doctor. He was made a member of the French Academy of Sciences in 1743 and a professor in the Paris Faculty of Medicine in 1745 and also in t ...
had said the same over 40 years earlier.Gaston de Lévis, ''Souvenirs et portraits, 1780-1789'', 1813
p. 240
/ref>


Biography

A native of
Tours Tours ( , ) is one of the largest cities in the region of Centre-Val de Loire, France. It is the prefecture of the department of Indre-et-Loire. The commune of Tours had 136,463 inhabitants as of 2018 while the population of the whole metro ...
, Indre-et-Loire, Armand Trousseau began his medical studies in his native town as a pupil of Pierre Fidele Bretonneau at the local general hospital. He later continued his studies in Paris, where he received his doctorate in 1825 and became adjunct faculty in 1827. In 1828, the French government assigned him to investigate epidemics ravaging some parts of southern France. After completing his mission the same year, Trousseau travelled to
Gibraltar ) , anthem = " God Save the King" , song = "Gibraltar Anthem" , image_map = Gibraltar location in Europe.svg , map_alt = Location of Gibraltar in Europe , map_caption = United Kingdom shown in pale green , mapsize = , image_map2 = Gibr ...
as a member of a commission to investigate
yellow fever Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains – particularly in the back – and headaches. Symptoms typically improve within five days. ...
. This work, and a monograph on laryngeal phthisis, led to his early recognition in Paris. In 1830 Trousseau became ''Médecin des hôpitaux'' through concours, and in 1832 received a position in public health with the central bureau while working as a physician in the Hôtel-Dieu under Joseph Claude Anthelme Récamier. In 1837 he received the great prize of the academy. In 1839 he was appointed physician at the Hôpital St. Antoine and eventually became Chair of therapy and pharmacology at the Paris medical faculty. In 1850 he assumed the Chair of clinical medicine and again commenced working in the Hôtel-Dieu. He was also active in politics, particularly after the
French Revolution of 1848 The French Revolution of 1848 (french: Révolution française de 1848), also known as the February Revolution (), was a brief period of civil unrest in France, in February 1848, that led to the collapse of the July Monarchy and the foundatio ...
, holding several positions including being a member of the legislative body. During his later years Trousseau developed
gastric cancer Stomach cancer, also known as gastric cancer, is a cancer that develops from the lining of the stomach. Most cases of stomach cancers are gastric carcinomas, which can be divided into a number of subtypes, including gastric adenocarcinomas. Lym ...
. Coincidentally, he previously described Trousseau sign of malignancy and developed a similar finding in himself. This cancer limited his activities and eventually proved fatal.


Legacy

Trousseau was instrumental in creating new modes of treatment of
croup Croup, also known as laryngotracheobronchitis, is a type of respiratory infection that is usually caused by a virus. The infection leads to swelling inside the trachea, which interferes with normal breathing and produces the classic symptoms ...
,
emphysema Emphysema, or pulmonary emphysema, is a lower respiratory tract disease, characterised by air-filled spaces ( pneumatoses) in the lungs, that can vary in size and may be very large. The spaces are caused by the breakdown of the walls of the alv ...
,
pleurisy Pleurisy, also known as pleuritis, is inflammation of the membranes that surround the lungs and line the chest cavity ( pleurae). This can result in a sharp chest pain while breathing. Occasionally the pain may be a constant dull ache. Other sy ...
,
goiter A goitre, or goiter, is a swelling in the neck resulting from an enlarged thyroid gland. A goitre can be associated with a thyroid that is not functioning properly. Worldwide, over 90% of goitre cases are caused by iodine deficiency. The term is ...
, and
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. ...
. He received the prize of the French Academy of Medicine for his classic essay on
laryngology Laryngology is a branch of medicine that deals with disorders, diseases and injuries of the larynx, colloquially known as the voice box. Laryngologists treat disorders of the larynx, including diseases that affects the voice, swallowing, or upper a ...
which originally appeared in 1837. He was the first in France to perform a
tracheotomy Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the trachea (windpipe). The r ...
, and he wrote a monograph on this as well as
intubation Intubation (sometimes entubation) is a medical procedure involving the insertion of a tube into the body. Patients are generally anesthetized beforehand. Examples include tracheal intubation, and the balloon tamponade with a Sengstaken-Blake ...
in 1851. His textbooks on clinical medicine and therapeutics were both extremely popular and translated into English. Trousseau coined the terms
aphasia Aphasia is an inability to comprehend or formulate language because of damage to specific brain regions. The major causes are stroke and head trauma; prevalence is hard to determine but aphasia due to stroke is estimated to be 0.1–0.4% in ...
and ''
forme fruste In medicine, a ''forme fruste'' ( French, "crude, or unfinished, form"; ''pl.'', ''formes frustes'') is an atypical or attenuated manifestation of a disease or syndrome, with the implications of incompleteness, partial presence or aborted state. Th ...
'' and popularized
eponym An eponym is a person, a place, or a thing after whom or which someone or something is, or is believed to be, named. The adjectives which are derived from the word eponym include ''eponymous'' and ''eponymic''. Usage of the word The term ''epon ...
s in disease description such as
Addison's disease Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrena ...
and
Hodgkin's lymphoma Hodgkin lymphoma (HL) is a type of lymphoma, in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the patient's lymph nodes. The condition w ...
. In 1833, Trousseau invented the Trousseau Tracheal Dilator, a blunt-nosed forceps designed to allow easier access to a
tracheostomy Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the trachea (windpipe). The r ...
stoma In botany, a stoma (from Greek ''στόμα'', "mouth", plural "stomata"), also called a stomate (plural "stomates"), is a pore found in the epidermis of leaves, stems, and other organs, that controls the rate of gas exchange. The pore is bo ...
. Trousseau was considered an outstanding teacher. Numerous students of his achieved fame in their own right, including Puerto Rican pro-independence leader, surgeon and
Légion d'honneur The National Order of the Legion of Honour (french: Ordre national de la Légion d'honneur), formerly the Royal Order of the Legion of Honour ('), is the highest French order of merit, both military and civil. Established in 1802 by Napoleon ...
laureate,
Ramón Emeterio Betances Ramón Emeterio Betances y Alacán (April 8, 1827 – September 16, 1898) was a Puerto Rican independence advocate and medical doctor. He was the primary instigator of the Grito de Lares revolution and is considered to be the father of the Pu ...
.Ojeda Reyes, Félix, ''El Desterrado de París'', pp. 20, 29–30 Trousseau’s son Georges Phillipe Trousseau (1833–1894) became the royal doctor of the
Kingdom of Hawaii The Hawaiian Kingdom, or Kingdom of Hawaiʻi ( Hawaiian: ''Ko Hawaiʻi Pae ʻĀina''), was a sovereign state located in the Hawaiian Islands. The country was formed in 1795, when the warrior chief Kamehameha the Great, of the independent islan ...
, and Armand's grandson was the distinguished
ophthalmologist Ophthalmology ( ) is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a med ...
Armand Henri Trousseau (1856–1910).


References


External links

* {{DEFAULTSORT:Trousseau, Armand 1801 births 1867 deaths People from Tours, France 19th-century French physicians Deputies of Eure-et-Loir Deaths from stomach cancer Burials at Père Lachaise Cemetery