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Declaration Of Helsinki
The Declaration of Helsinki (DoH, ) is a set of ethical principles regarding human experimentation developed originally in 1964 for the medical community by the World Medical Association (WMA). It is widely regarded as the cornerstone document on human research ethics. It is not a legally binding instrument under international law, but instead draws its authority from the degree to which it has been codified in, or influenced, national or regional legislation and regulations. Its role was described by a Brazilian forum in 2000 in these words: "Even though the Declaration of Helsinki is the responsibility of the World Medical Association, the document should be considered the property of all humanity." Principles The Declaration is morally binding on physicians, and that obligation overrides any national or local laws or regulations, if the Declaration provides for a higher standard of protection of humans than the latter. Investigators still have to abide by local legislation b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Experimentation
Human subject research is systematic, scientific investigation that can be either interventional (a "trial") or observational (no "test article") and involves human beings as research subjects, commonly known as test subjects. Human subject research can be either medical (clinical) research or non-medical (e.g., social science) research. Systematic investigation incorporates both the collection and analysis of data in order to answer a specific question. Medical human subject research often involves analysis of biological specimens, epidemiological and behavioral studies and medical chart review studies. (A specific, and especially heavily regulated, type of medical human subject research is the " clinical trial", in which drugs, vaccines and medical devices are evaluated.) On the other hand, human subject research in the social sciences often involves surveys which consist of questions to a particular group of people. Survey methodology includes questionnaires, interviews ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zidovudine
Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. It may be used to prevent mother-to-child spread during birth or after a needlestick injury or other potential exposure. It is sold both by itself and together as lamivudine/zidovudine and abacavir/lamivudine/zidovudine. It can be used by mouth or by slow injection into a vein. Common side effects include headaches, fever, and nausea. Serious side effects include liver problems, muscle damage, and high blood lactate levels. It is commonly used in pregnancy and appears to be safe for the fetus. ZDV is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. It works by inhibiting the enzyme reverse transcriptase that HIV uses to make DNA and therefore decreases replication of the virus. Zidovudine was first described in 1964. It was resynthesize ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
São Paulo
São Paulo (; ; Portuguese for 'Paul the Apostle, Saint Paul') is the capital of the São Paulo (state), state of São Paulo, as well as the List of cities in Brazil by population, most populous city in Brazil, the List of largest cities in the Americas, Americas, and both the Western Hemisphere, Western and Southern Hemispheres. Listed by the Globalization and World Cities Research Network (GaWC) as an global city, alpha global city, it exerts substantial international influence in commerce, finance, arts, and entertainment. It is the List of largest cities#List, largest urban area by population outside Asia and the most populous Geographical distribution of Portuguese speakers, Portuguese-speaking city in the world. The city's name honors Paul the Apostle and people from the city are known as ''paulistanos''. The city's Latin motto is ''Non ducor, duco'', which translates as "I am not led, I lead." Founded in 1554 by Jesuit priests, the city was the center of the ''bandeirant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cairo
Cairo ( ; , ) is the Capital city, capital and largest city of Egypt and the Cairo Governorate, being home to more than 10 million people. It is also part of the List of urban agglomerations in Africa, largest urban agglomeration in Africa, List of largest cities in the Arab world, the Arab world, and List of largest metropolitan areas of the Middle East, the Middle East. The Greater Cairo metropolitan area is List of largest cities, one of the largest in the world by population with over 22.1 million people. The area that would become Cairo was part of ancient Egypt, as the Giza pyramid complex and the ancient cities of Memphis, Egypt, Memphis and Heliopolis (ancient Egypt), Heliopolis are near-by. Located near the Nile Delta, the predecessor settlement was Fustat following the Muslim conquest of Egypt in 641 next to an existing ancient Roman empire, Roman fortress, Babylon Fortress, Babylon. Subsequently, Cairo was founded by the Fatimid Caliphate, Fatimid dynasty in 969. It ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hastings Center
The Hastings Center for Bioethics is an independent, nonpartisan bioethics research institute in Garrison, New York. Its mission is to address ethical issues in health care, science, and technology. Through its projects and publications and its public engagement, the Center aims to influence the ideas of health policy-makers, regulators, health care professionals, lawyers, journalists, educators, and students. The Center is funded by grants and private donations. It was known as The Hastings Center before 2025. Founding The Hastings Center for Bioethics was founded in 1969 by Daniel Callahan and Willard Gaylin, originally as the Institute of Society, Ethics, and the Life Sciences. It was first located in Hastings-on-Hudson, New York, and is now in Garrison, New York, on the former Woodlawn estate designed by Richard Upjohn. In the early years, the Center identified four core issues as its domain: ''population'', including respect for procreative freedom; ''behavior'', which respo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Medical Association
The American Medical Association (AMA) is an American professional association and lobbying group of physicians and medical students. This medical association was founded in 1847 and is headquartered in Chicago, Illinois. Membership was 271,660 in 2022. The AMA's stated mission is "to promote the art and science of medicine and the betterment of public health." The organization was founded with the goal to raise the standards of medicine in the 19th century primarily through gaining control of education and licensing. In the 20th century, the AMA has frequently lobbied to restrict the supply of physicians, contributing to a doctor shortage in the United States. The organization has also lobbied against allowing physician assistants and other health care providers to perform basic forms of health care. The organization has historically lobbied against various forms of government-run health insurance. The Association also publishes the '' Journal of the American Medical Assoc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Distributive Justice
Distributive justice concerns the Social justice, socially just Resource allocation, allocation of resources, goods, opportunity in a society. It is concerned with how to allocate resources fairly among members of a society, taking into account factors such as wealth, income, and social status. Often contrasted with procedural justice, just process and Equal opportunity, formal equal opportunity, distributive justice concentrates on outcomes (substantive equality). This subject has been given considerable attention in philosophy and the social sciences. Theorists have developed widely different conceptions of distributive justice. These have contributed to debates around the arrangement of social, political and economic institutions to promote the just distribution of benefits and burdens within a society. Most contemporary theories of distributive justice rest on the precondition of material scarcity. From that precondition arises the need for principles to resolve competing intere ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hastings Center Report
The ''Hastings Center Report'' is a bimonthly peer-reviewed academic journal of bioethics. It is published by Wiley-Blackwell on behalf of the Hastings Center (Garrison, New York). The editor-in-chief is Gregory Kaebnick. According to the ''Journal Citation Reports'', the journal has a 2021 impact factor of 4.298. In 2018, it ranked it 5th out of 16 journals in the category "Medical Ethics". The journal focuses on legal, moral, and social issues in medicine and the life sciences This list of life sciences comprises the branches of science that involve the scientific study of life – such as microorganisms, plants, and animals including human beings. This science is one of the two major branches of natural science, .... It publishes a variety of article types that may take many forms: * articles that explore philosophical and ethical issues in medicine, health care, technology, medical research, the use of human subjects in research, and the environment * reports or revie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Utilitarian
In ethical philosophy, utilitarianism is a family of normative ethical theories that prescribe actions that maximize happiness and well-being for the affected individuals. In other words, utilitarian ideas encourage actions that lead to the greatest good for the greatest number. Although different varieties of utilitarianism admit different characterizations, the basic idea that underpins them all is, in some sense, to maximize utility, which is often defined in terms of well-being or related concepts. For instance, Jeremy Bentham, the founder of utilitarianism, described ''utility'' as the capacity of actions or objects to produce benefits, such as pleasure, happiness, and good, or to prevent harm, such as pain and unhappiness, to those affected. Utilitarianism is a version of consequentialism, which states that the consequences of any action are the only standard of right and wrong. Unlike other forms of consequentialism, such as egoism and altruism, egalitarian utilita ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marcia Angell
Marcia Angell (; born April 20, 1939) is an American physician, author, and the first woman to serve as editor-in-chief of ''The New England Journal of Medicine''. She is currently a Senior Lecturer in the Department of Global Health and Social Medicine at Harvard Medical School in Boston, Massachusetts. Biography After completing undergraduate studies in chemistry and mathematics at James Madison University in Harrisonburg, Virginia, Angell spent a year as a Fulbright Scholar studying microbiology in Frankfurt, Germany. After receiving her M.D. from Boston University School of Medicine in 1967, Angell trained in both internal medicine and anatomic pathology and is a board-certified pathologist. Angell is a frequent contributor to medical journals as well as in the popular media, where she has offered her perspective on topics including medical ethics, health policy, psychiatry, the opioid epidemic, the nature of medical evidence, the interface of medicine and the law, and end-o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Services (HHS). Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its scientific research through the NIH Intramural Research Program (IRP) and provides significant biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomedical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
