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El Tor
El Tor is a particular strain of the bacterium ''Vibrio cholerae'', the causative agent of cholera. Also known as ''V. cholerae'' biotype eltor, it has been the dominant strain in the seventh global cholera pandemic. It is distinguished from the classic strain at a genetic level, although both are in the serogroup O1 and both contain Inaba, Ogawa and Hikojima serotypes. It is also distinguished from classic biotypes by the production of hemolysins. History At the turn of the 20th century, the Ottoman government established six medical stations along the coast of the Sinai Peninsula to cater to pilgrims returning from Mecca. One of them was in El Tor (A' Tur as it is called today). Sick passengers were dropped off in one of the stations for treatment. In 1905, Felix Gotschlich, a German physician at the El Tor station identified vibrios in stool specimen of two pilgrims returning from Mecca. Though the pilgrims failed to show ante or post mortem evidence of cholera, the vib ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strain (biology)
In biology, a strain is a genetic variant, a subtype or a culture within a biological species. Strains are often seen as inherently artificial concepts, characterized by a specific intent for genetic isolation. This is most easily observed in microbiology where strains are derived from a single cell colony and are typically quarantined by the physical constraints of a Petri dish. Strains are also commonly referred to within virology, botany, and with rodents used in experimental studies. Microbiology and virology It has been said that "there is no universally accepted definition for the terms 'strain', ' variant', and 'isolate' in the virology community, and most virologists simply copy the usage of terms from others". A strain is a genetic variant or subtype of a microorganism such as a bacterial strain or a specific strain of a virus, or fungus. For example, a "flu strain" is a certain biological form of the influenza or "flu" virus. These flu strains are characterized ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vibrio Cholerae
''Vibrio cholerae'' is a species of Gram-negative bacteria, Gram-negative, Facultative anaerobic organism, facultative anaerobe and Vibrio, comma-shaped bacteria. The bacteria naturally live in Brackish water, brackish or saltwater where they attach themselves easily to the chitin-containing shells of crabs, shrimp, and other shellfish. Some strains of ''V. cholerae'' are pathogenic to humans and cause a deadly disease called cholera, which can be derived from the consumption of undercooked or raw marine life species or drinking contaminated water. ''V. cholerae'' was first described by Félix-Archimède Pouchet in 1849 as some kind of protozoa. Filippo Pacini correctly identified it as a bacterium and from him, the scientific name is adopted. The bacterium as the cause of cholera was discovered by Robert Koch in 1884. Sambhu Nath De isolated the cholera toxin and demonstrated the toxin as the cause of cholera in 1959. The bacterium has a flagellum (a tail like structure) at one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cholera
Cholera () is an infection of the small intestine by some Strain (biology), strains of the Bacteria, bacterium ''Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea lasting a few days. Vomiting and muscle cramps may also occur. Diarrhea can be so severe that it leads within hours to severe dehydration and electrolyte imbalance. This can in turn result in Enophthalmia, sunken eyes, cold or cyanotic skin, decreased skin elasticity, wrinkling of the hands and feet, and, in severe cases, death. Symptoms start two hours to five days after exposure. Cholera is caused by a number of Serotype, types of ''Vibrio cholerae'', with some types producing more severe disease than others. It is spread mostly by Waterborne diseases, unsafe water and Foodborne illness, unsafe food that has been contaminated with human feces containing the bacteria. Undercooked shellfish is a common source. Humans are the only known host fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seventh Cholera Pandemic
The seventh cholera pandemic is the seventh major outbreak of cholera beginning in 1961 and continuing to the present. Cholera has become endemic in many countries. In 2017, WHO announced a global strategy aiming to end the pandemic by 2030. This pandemic is based on the strain called El Tor; it started in Indonesia in 1961 and spread to East Pakistan (now Bangladesh), by 1963. It went to India in 1964, and into the Soviet Union by 1966. In July 1970, there was an outbreak in Odessa (now Ukraine) and in 1972 there were reports of outbreaks in Baku, but the Soviet Union suppressed this information. Cholera reached Italy in 1973 from North Africa. Japan and the South Pacific saw a few outbreaks by the late 1970s. In 1971, the number of cases reported worldwide was 155,000. But in 1991, it reached 570,000. The spread of the disease was helped by modern transportation and mass migrations. Mortality rates, however, dropped markedly as governments began modern curative and preventive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serotype
A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals. These microorganisms, viruses, or Cell (biology), cells are classified together based on their shared reactivity between their surface antigens and a particular antiserum, allowing the classification of organisms to a Infraspecific name, level below the species. A group of serovars with common antigens is called a serogroup or sometimes ''serocomplex''. Serotyping often plays an essential role in determining species and subspecies. The ''Salmonella'' genus of bacteria, for example, has been determined to have over 2600 serotypes. ''Vibrio cholerae'', the species of bacteria that causes cholera, has over 200 serotypes, based on cell antigens. Only two of them have been observed to produce the potent enterotoxin that results in cholera: O1 and O139. Serotypes were discovered in hemolytic streptococci by the American microbiologist Rebecca Lancefield i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ottoman Empire
The Ottoman Empire (), also called the Turkish Empire, was an empire, imperial realm that controlled much of Southeast Europe, West Asia, and North Africa from the 14th to early 20th centuries; it also controlled parts of southeastern Central Europe, between the early 16th and early 18th centuries. The empire emerged from a Anatolian beyliks, ''beylik'', or principality, founded in northwestern Anatolia in by the Turkoman (ethnonym), Turkoman tribal leader Osman I. His successors Ottoman wars in Europe, conquered much of Anatolia and expanded into the Balkans by the mid-14th century, transforming their petty kingdom into a transcontinental empire. The Ottomans ended the Byzantine Empire with the Fall of Constantinople, conquest of Constantinople in 1453 by Mehmed II. With its capital at History of Istanbul#Ottoman Empire, Constantinople (modern-day Istanbul) and control over a significant portion of the Mediterranean Basin, the Ottoman Empire was at the centre of interacti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
El Tor, Egypt
El Tor ( ''/'' ), also romanized as ''Al-Tur'' and ''At-Tur'' and known as ''Tur Sinai'', formerly Raithu, is a small city and the capital of the South Sinai Governorate of Egypt. The name of the city comes from the Arabic term for the mountain where the prophet Moses is believed to have received the Tablets of the Law from God; this mountain is designated ''Jabal Al Tor''. At-Tur itself appears to have been founded in the 13th century near the site of the ancient Raythou (medieval ''Raya''). The El tor strain of cholera was discovered there in 1905. It was a quarantine camp for Muslim pilgrims returning from Hajj (the Islamic pilgrimage to Mecca). Known for its springs, the city is an important tourist destination in the South Sinai Governorate along with Sharm El Sheikh and Saint Catherine. History Monastery The Raithu desert is situated around El Tor, between Saint Catherine and the Red Sea. It is part of the Archdiocese of Mount Sinai and Raithu of the Eastern Orthodox ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mecca
Mecca, officially Makkah al-Mukarramah, is the capital of Mecca Province in the Hejaz region of western Saudi Arabia; it is the Holiest sites in Islam, holiest city in Islam. It is inland from Jeddah on the Red Sea, in a narrow valley above sea level. Its metropolitan population in 2022 was 2.4million, making it the List of cities in Saudi Arabia by population, third-most populated city in Saudi Arabia after Riyadh and Jeddah. Around 44.5% of the population are Saudis, Saudi citizens and around 55.5% are Muslim world, Muslim foreigners from other countries. Pilgrims more than triple the population number every year during the Pilgrimage#Islam, pilgrimage, observed in the twelfth Islamic calendar, Hijri month of . With over 10.8 million international visitors in 2023, Mecca was one of the ten List of cities by international visitors, most visited cities in the world. Mecca is generally considered "the fountainhead and cradle of Islam". Mecca is revered in Islam as the birthp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1961–1975 Cholera Pandemic
The seventh cholera pandemic is the seventh major outbreak of cholera beginning in 1961 and continuing to the present. Cholera has become endemic in many countries. In 2017, WHO announced a global strategy aiming to end the pandemic by 2030. This pandemic is based on the strain called El Tor; it started in Indonesia in 1961 and spread to East Pakistan (now Bangladesh), by 1963. It went to India in 1964, and into the Soviet Union by 1966. In July 1970, there was an outbreak in Odessa (now Ukraine) and in 1972 there were reports of outbreaks in Baku, but the Soviet Union suppressed this information. Cholera reached Italy in 1973 from North Africa. Japan and the South Pacific saw a few outbreaks by the late 1970s. In 1971, the number of cases reported worldwide was 155,000. But in 1991, it reached 570,000. The spread of the disease was helped by modern transportation and mass migrations. Mortality rates, however, dropped markedly as governments began modern curative and preventive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulawesi
Sulawesi ( ), also known as Celebes ( ), is an island in Indonesia. One of the four Greater Sunda Islands, and the List of islands by area, world's 11th-largest island, it is situated east of Borneo, west of the Maluku Islands, and south of Mindanao and the Sulu Archipelago. Within Indonesia, only Sumatra, Borneo, and New Guinea, Papua are larger in territory, and only Java and Sumatra are more populous. The landmass of Sulawesi includes four peninsulas: the northern Minahasa Peninsula, the East Peninsula, Sulawesi, East Peninsula, the South Peninsula, Sulawesi, South Peninsula, and the Southeast Peninsula, Sulawesi, Southeast Peninsula. Three gulfs separate these peninsulas: the Gulf of Tomini between the northern Minahasa and East peninsulas, the Tolo Gulf between the East and Southeast peninsulas, and the Bone Gulf between the South and Southeast peninsulas. The Strait of Makassar runs along the western side of the island and separates the island from Borneo. Etymology The n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bangladesh
Bangladesh, officially the People's Republic of Bangladesh, is a country in South Asia. It is the List of countries and dependencies by population, eighth-most populous country in the world and among the List of countries and dependencies by population density, most densely populated with a population of over 171 million within an area of . Bangladesh shares land borders with India to the north, west, and east, and Myanmar to the southeast. It has a coastline along the Bay of Bengal to its south and is separated from Bhutan and Nepal by the Siliguri Corridor, and from China by the List of Indian states, Indian state of Sikkim to its north. Dhaka, the capital and list of cities and towns in Bangladesh, largest city, is the nation's political, financial, and cultural centre. Chittagong is the second-largest city and the busiest port of the country. The territory of modern Bangladesh was a stronghold of many List of Buddhist kingdoms and empires, Buddhist and List of Hindu empir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
India
India, officially the Republic of India, is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area; the List of countries by population (United Nations), most populous country since 2023; and, since its independence in 1947, the world's most populous democracy. Bounded by the Indian Ocean on the south, the Arabian Sea on the southwest, and the Bay of Bengal on the southeast, it shares land borders with Pakistan to the west; China, Nepal, and Bhutan to the north; and Bangladesh and Myanmar to the east. In the Indian Ocean, India is near Sri Lanka and the Maldives; its Andaman and Nicobar Islands share a maritime border with Thailand, Myanmar, and Indonesia. Modern humans arrived on the Indian subcontinent from Africa no later than 55,000 years ago., "Y-Chromosome and Mt-DNA data support the colonization of South Asia by modern humans originating in Africa. ... Coalescence dates for most non-European populations averag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
