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David H. Koch Institute For Integrative Cancer Research
The Koch Institute for Integrative Cancer Research at MIT ( ; also referred to as the Koch Institute, KI, or CCR/KI) is a cancer research center affiliated with the Massachusetts Institute of Technology (MIT) located in Cambridge, Massachusetts, United States. The institute is one of eight National Cancer Institute-designated basic research centers in the United States. The institute was launched in October 2007 with a $100 million grant from David H. Koch and the research facility opened in December 2010, replacing the MIT Center for Cancer Research (CCR). The institute is affiliated with 25 MIT faculty members in both the Schools of Engineering and Science. History In 1974, the Center for Cancer Research was founded by 1969 Nobel laureate Salvador Luria to study basic biological processes related to cancer. The center researches the genetic and molecular basis of cancer, how alterations in cellular processes affect cell growth and behavior, and how the immune system deve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Koch Institute Logo
Koch may refer to: People * Koch (surname), people with this surname * Koch dynasty, a dynasty in Assam and Bengal, north east India * Koch family * Koch people (or Koche), an ethnic group originally from the ancient Koch kingdom in north east India ** Koch language, a language spoken in India and Bangladesh * Koch, an alternate name of the Rabha tribe in northeast India and surrounding countries * Koch Kingdom, in and around Assam Places * Koch (crater), a crater on the Moon * Koch, Iran (other), places in Iran * Koch, Łódź Voivodeship, a village in central Poland * Koch, Mississippi, United States * Koch, South Sudan, a village in Unity State, South Sudan * Koch Bihar, a princely state in north east India * Koch County, an administrative area in Unity State, South Sudan * Koch Kingdom, Assam, 13th-16th centuries Businesses * Koch Entertainment LP, now known as E1 Entertainment ** Koch Records, former name of Entertainment One Music * Koch Industries, pet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncogene
An oncogene is a gene that has the potential to cause cancer. In tumor cells, these genes are often mutated, or expressed at high levels.Kimball's Biology Pages. "Oncogenes" Free full text Most normal cells will undergo a programmed form of rapid cell death () when critical functions are altered and malfunctioning. Activated oncogenes can cause those cells designated for apoptosis to survive and proliferate instead. Most oncogenes began as proto-oncogenes: normal genes involved in cell growth and proliferation or inhibition of apoptosis. If, through mutation, normal genes promoting cellular growth are up-regulated (gain-of-function mutation), they will predis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanotechnology
Nanotechnology, also shortened to nanotech, is the use of matter on an atomic, molecular, and supramolecular scale for industrial purposes. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology. A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative, which defined nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers (nm). This definition reflects the fact that quantum mechanical effects are important at this quantum-realm scale, and so the definition shifted from a particular technological goal to a research category inclusive of all types of research and technologies that deal with the special properties of matter which occur below the given size threshold. It is therefore commo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Charle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Koch Biology Building
The Massachusetts Institute of Technology occupies a tract in Cambridge, Massachusetts, United States. The campus spans approximately one mile (1.6 km) of the north side of the Charles River basin directly opposite the Back Bay neighborhood of Boston, Massachusetts. The campus includes dozens of buildings representing diverse architectural styles and shifting campus priorities over MIT's history. MIT's architectural history can be broadly split into four eras: the Boston campus, the new Cambridge campus before World War II, the "Cold War" development, and post-Cold War buildings. Each era was marked by distinct builds representing neoclassical, modernist, brutalist, and deconstructivist styles which alternatively represent a commitment to utilitarian minimalism and embellished exuberance. Campus organization The geographical organization of the MIT campus is much easier to understand by referring to the MIT map, in online interactive, or downloadable printabl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prostate Cancer
Prostate cancer is cancer of the prostate. Prostate cancer is the second most common cancerous tumor worldwide and is the fifth leading cause of cancer-related mortality among men. The prostate is a gland in the male reproductive system that surrounds the urethra just below the bladder. It is located in the hypogastric region of the abdomen. To give an idea of where it is located, the bladder is superior to the prostate gland as shown in the image The rectum is posterior in perspective to the prostate gland and the ischial tuberosity of the pelvic bone is inferior. Only those who have male reproductive organs are able to get prostate cancer. Most prostate cancers are slow growing. Cancerous cells may spread to other areas of the body, particularly the bones and lymph nodes. It may initially cause no symptoms. In later stages, symptoms include pain or difficulty urinating, blood in the urine, or pain in the pelvis or back. Benign prostatic hyperplasia may produce similar sym ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Engineering
Chemical engineering is an engineering field which deals with the study of operation and design of chemical plants as well as methods of improving production. Chemical engineers develop economical commercial processes to convert raw materials into useful products. Chemical engineering uses principles of chemistry, physics, mathematics, biology, and economics to efficiently use, produce, design, transport and transform energy and materials. The work of chemical engineers can range from the utilization of nanotechnology and nanomaterials in the laboratory to large-scale industrial processes that convert chemicals, raw materials, living cells, microorganisms, and energy into useful forms and products. Chemical engineers are involved in many aspects of plant design and operation, including safety and hazard assessments, process design and analysis, modeling, control engineering, chemical reaction engineering, nuclear engineering, biological engineering, construction specificatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Koch Industries
Koch Industries, Inc. ( ) is an American privately held multinational conglomerate corporation based in Wichita, Kansas and is the second-largest privately held company in the United States, after Cargill. Its subsidiaries are involved in the manufacturing, refining, and distribution of petroleum, chemicals, energy, fiber, intermediates and polymers, minerals, fertilizer, pulp and paper, chemical technology equipment, cloud computing, finance, raw materials trading, and investments. Koch owns Flint Hills Resources, Georgia-Pacific, Guardian Industries, Infor, Invista, KBX, Koch Ag & Energy Solutions, Koch Engineered Solutions, Koch Investments Group, Koch Minerals & Trading, and Molex. The firm employs 122,000 people in 60 countries, with about half of its business in the United States. The company was founded by its namesake, Fred C. Koch, in 1940 after he developed an innovative crude oil refining process. Fred C. Koch died in 1967 and his majority interest in the company wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ludwig Cancer Research
Ludwig Cancer Research is an international community of scientists focused on cancer research, with the goal of preventing and controlling cancer. It encompasses the Ludwig Institute for Cancer Research, an international non-profit organization founded in 1971 by philanthropist Daniel K. Ludwig. The Institute is headquartered in New York City, with a European office located in Zurich. In addition, six Ludwig Centers were established at leading US cancer research institutions. Together, the Institute and Centers are known as Ludwig Cancer Research. Since its founding in 1971, Ludwig Cancer Research has committed more than US$2.5 billion to cancer research. Ludwig Cancer Research focuses on both basic research and translational research, with specific emphasis on cell biology, genomics, immunology, neuroscience, prevention, cell signaling, stem cells, therapeutics, and tumor biology, as well as clinical trials and the design and development of small molecules with drug-like proper ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Susan Hockfield
Susan Hockfield (born March 24, 1951) is an American neuroscientist who served as the sixteenth president of the Massachusetts Institute of Technology from December 2004 through June 2012. Hockfield succeeded Charles M. Vest and was succeeded by L. Rafael Reif, who had served in her administration as Provost. Hockfield was the first biologist and the first woman to serve as the Institute's president. Hockfield currently serves as a Professor of Neuroscience in MIT's Department of Brain and Cognitive Sciences, a Joint Professor of Work and Organization Studies in MIT’s Sloan School of Management, and a member of the Koch Institute for Integrative Cancer Research. She is also a director oBreak Through Cancer Fidelity Non-Profit Management Foundation [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phillip Sharp
Phillip Allen Sharp (born June 6, 1944) is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for "the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence". He has been selected to receive the 2015 Othmer Gold Medal. Research Sharp's current research focuses on small RNAs and other types of non-coding RNAs. His laboratory works to identify the target mRNAs of microRNAs (miRNAs), and has discovered a class of miRNAs that are produced from sequences adjacent to transcription start sites. His laboratory also studies how miRNA gene regulation functions in angiogenesis and cellular stress. Biography Sharp was born in Falmouth, Kentucky, the son of Kathrin (Colvin) and Joseph Walter Sharp. He marri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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