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Andrew Huxley
Sir Andrew Fielding Huxley (22 November 191730 May 2012) was an English physiologist and biophysicist. He was born into the prominent Huxley family. After leaving Westminster School in central London, he went to Trinity College, Cambridge on a scholarship, after which he joined Alan Lloyd Hodgkin to study nerve impulses. Their eventual discovery of the basis for propagation of nerve impulses (called an action potential) earned them the Nobel Prize in Physiology or Medicine in 1963. They made their discovery from the giant axon of the Atlantic squid. Soon after the outbreak of the Second World War, Huxley was recruited by the British Anti-Aircraft Command and later transferred to the Admiralty. After the war he resumed research at the University of Cambridge, where he developed interference microscopy that would be suitable for studying muscle fibres. In 1952, he was joined by a German physiologist Rolf Niedergerke. Together they discovered in 1954 the mechanism of musc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Andrew D
Andrew is the English form of a given name common in many countries. In the 1990s, it was among the top ten most popular names given to boys in English-speaking countries. "Andrew" is frequently shortened to "Andy" or "Drew". The word is derived from the el, Ἀνδρέας, '' Andreas'', itself related to grc, ἀνήρ/ἀνδρός ''aner/andros'', "man" (as opposed to "woman"), thus meaning "manly" and, as consequence, "brave", "strong", "courageous", and "warrior". In the King James Bible, the Greek "Ἀνδρέας" is translated as Andrew. Popularity Australia In 2000, the name Andrew was the second most popular name in Australia. In 1999, it was the 19th most common name, while in 1940, it was the 31st most common name. Andrew was the first most popular name given to boys in the Northern Territory in 2003 to 2015 and continuing. In Victoria, Andrew was the first most popular name for a boy in the 1970s. Canada Andrew was the 20th most popular name chosen for m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Huxley Family
The Huxley family is a British family; several of its members have excelled in science, medicine, arts and literature. The family also includes members who occupied senior positions in the public service of the United Kingdom. The patriarch of the family was the zoologist and comparative anatomist Thomas Henry Huxley (1825–1895). His grandsons include Aldous Huxley (author of ''Brave New World'' and '' The Doors of Perception'') and his brother Julian Huxley (an evolutionary biologist and the first director of UNESCO) and the Nobel laureate physiologist Andrew Huxley. Family tree Thomas Henry Huxley Thomas Henry Huxley (1825–1895) was an English biologist. Known as "Darwin's Bulldog" for his defence of Charles Darwin's theory of evolution. Mostly a self-educated man, he had an extraordinary influence on the British educated public. He was instrumental in developing scientific education in Britain, and opposed those Christian leaders who tried to stifle sc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elizabeth II
Elizabeth II (Elizabeth Alexandra Mary; 21 April 1926 – 8 September 2022) was Queen of the United Kingdom and other Commonwealth realms from 6 February 1952 until her death in 2022. She was queen regnant of 32 sovereign states during her lifetime, and was head of state of 15 realms at the time of her death. Her reign of 70 years and 214 days was the longest of any British monarch and the longest verified reign of any female monarch in history. Elizabeth was born in Mayfair, London, as the first child of the Duke and Duchess of York (later King George VI and Queen Elizabeth The Queen Mother). Her father acceded to the throne in 1936 upon the abdication of his brother Edward VIII, making the ten-year-old Princess Elizabeth the heir presumptive. She was educated privately at home and began to undertake public duties during the Second World War, serving in the Auxiliary Territorial Service. In November 1947, she married Philip Mountbatten, a former prince ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
President Of The Royal Society
The president of the Royal Society (PRS) is the elected Head of the Royal Society of London who presides over meetings of the society's council. After informal meetings at Gresham College, the Royal Society was officially founded on 28 November 1660 when a group of academics decided to find "a College for the Promoting of Mathematicall Experimentall Learning", acquiring a Royal Charter on 15 July 1662. The Royal Charter nominated William Brouncker as president, and stipulated that future presidents should be elected by the Council and Fellows of the society at anniversary meetings each year on St. Andrew's Day (30 November). The details of the presidency were described by the second Royal Charter, which did not set any limit on how long a president could serve. There were considerable fluctuations in the president's term of office until well into the 19th century. By then, sentiment had turned against electing wealthy amateurs solely because they might become patrons of the soc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sliding Filament Theory
The sliding filament theory explains the mechanism of muscle contraction based on muscle proteins that slide past each other to generate movement. According to the sliding filament theory, the myosin ( thick filaments) of muscle fibers slide past the actin ( thin filaments) during muscle contraction, while the two groups of filaments remain at relatively constant length. The theory was independently introduced in 1954 by two research teams, one consisting of Andrew Huxley and Rolf Niedergerke from the University of Cambridge, and the other consisting of Hugh Huxley and Jean Hanson from the Massachusetts Institute of Technology. It was originally conceived by Hugh Huxley in 1953. Andrew Huxley and Niedergerke introduced it as a "very attractive" hypothesis. Before the 1950s there were several competing theories on muscle contraction, including electrical attraction, protein folding, and protein modification. The novel theory directly introduced a new concept called cross-bridge t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rolf Niedergerke
Rolf Nidergerke (30 April 1921 – 27 December 2011) was a German physiologist and physician, and one of the discoverers of the sliding filament theory of muscle contraction. He and Andrew Huxley, complimenting the independent works of Hugh Huxley and Jean Hanson, revealed that muscle contraction is due to shortening of the muscle fibres. He studied medicine throughout the Second World War, and obtained his MD degree as the war ended in 1945. After a brief practise in his hometown, he chose a research career. He became associated with Huxley, whom he joined at Cambridge University. Together they published a landmark paper in ''Nature'' in 1954, which became the foundation of muscle mechanics. Early life and education Rolf Niedergerke was born and educated in Mülheim an der Ruhr. The turmoil of the Second World War almost interrupted his medical course when he was at Freiburg University. As a student of medicine he was exempted from conscription to serve in the German Army. How ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interference Microscopy
Interference microscopy involving measurements of differences in the path between two beams of light that have been split. Types include: * Classical interference microscopy * Differential interference contrast microscopy * Fluorescence interference contrast microscopy * Interference reflection microscopy Interference reflection microscopy (IRM), also called Reflection Interference Contrast Microscopy (RICM) or Reflection Contrast Microscopy (RCM) depending on the context, is an optical microscopy technique that leverages interference effects to fo ... See also * Phase contrast microscopy References {{science-stub Microscopy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Second World War
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing military alliances: the Allies and the Axis powers. World War II was a total war that directly involved more than 100 million personnel from more than 30 countries. The major participants in the war threw their entire economic, industrial, and scientific capabilities behind the war effort, blurring the distinction between civilian and military resources. Aircraft played a major role in the conflict, enabling the strategic bombing of population centres and deploying the only two nuclear weapons ever used in war. World War II was by far the deadliest conflict in human history; it resulted in 70 to 85 million fatalities, mostly among civilians. Tens of millions died due to genocides (including the Holocaust), starvat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Loligo Pealei
The longfin inshore squid (''Doryteuthis pealeii'') is a species of squid of the family Loliginidae. Description This species of squid is often seen with a reddish hue, but like many types of squid can manipulate its color, varying from a deep red to a soft pink. The dorsal mantle length of some males can reach up to 50 cm, although most squid commercially harvested are smaller than 30 cm long. This species exhibits sexual dimorphism, with most males growing faster and reaching larger sizes than females. Distribution The longfin inshore squid is found in the North Atlantic, schooling in continental shelf and slope waters from Newfoundland to the Gulf of Venezuela. It is commercially exploited, especially in the range from the Southern Georges Bank to Cape Hatteras. The population makes seasonal migrations that appear to be related to bottom water temperatures; they move offshore during late autumn to overwinter along the edge of the continental shelf and return in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Squid Giant Axon
The squid giant axon is the very large (up to 1.5 mm in diameter; typically around 0.5 mm) axon that controls part of the water jet propulsion system in squid. It was first described by L. W. Williams in 1909, but this discovery was forgotten until English zoologist and neurophysiologist J. Z. Young demonstrated the axon's function in the 1930s while working in the Stazione Zoologica in Naples, the Marine Biological Association in Plymouth and the Marine Biological Laboratory in Woods Hole. Squids use this system primarily for making brief but very fast movements through the water. On the underside of the squid's body, between the head and the mantle, is a siphon through which water can be rapidly expelled by the fast contractions of the body wall muscles of the animal. This contraction is initiated by action potentials in the giant axon. Action potentials travel faster in a larger axon than a smaller one, and squid have evolved the giant axon to improve the s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alan Lloyd Hodgkin
Sir Alan Lloyd Hodgkin (5 February 1914 – 20 December 1998) was an English physiologist and biophysicist who shared the 1963 Nobel Prize in Physiology or Medicine with Andrew Huxley and John Eccles. Early life and education Hodgkin was born in Banbury, Oxfordshire, on 5 February 1914. He was the oldest of three sons of Quakers George Hodgkin and Mary Wilson Hodgkin. His father was the son of Thomas Hodgkin and had read for the Natural Science Tripos at Cambridge where he had befriended electrophysiologist Keith Lucas. Because of poor eyesight he was unable to study medicine and eventually ended up working for a bank in Banbury. As members of the Society of Friends, George and Mary opposed the Military Service Act of 1916 and had to endure a great deal of abuse from their local community, including an attempt to throw George in one of the town canals. In 1916 George Hodgkin travelled to Armenia as part of an investigation of distress. Moved by the misery and suffering o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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