People and fictional characters
* Wes (given name), including a list of people and fictional characters with the name * Wes Madiko (1964–2021), Cameroonian musician better known as "Wes" * William Wesley (born 1964), basketball facilitator known as "Worldwide Wes" * Wesley "Wes" Correa (born 1962), American-Puerto Rican professional basketball playerComputing, science, and technology
* Warehouse execution system, a software system used in distribution centers * Whole exome sequencing, a technique for sequencing the expressed genes in a genome *Organizations
* Wiltshire Emergency Services, the collaboration of emergency services in Wiltshire, England * Women's Engineering Society. A professional society of women engineers, scientists and technologists set up 1919. * World Education Services, a non-profit organization whose goal is to evaluate international credentialsTransportation
* WES,, code used for Wesel (district) on German vehicle registration plates * WES Commuter Rail (Westside Express Service), a commuter rail line in Oregon, United States {{disambiguation