Vindoline is a chemical precursor to
vinblastine
Vinblastine (VBL), sold under the brand name Velban among others, is a chemotherapy medication, typically used with other medications, to treat a number of types of cancer. This includes Hodgkin's lymphoma, non-small cell lung cancer, bladder ca ...
.
Vindoline is formed through biosynthesis from
Tabersonine
Tabersonine is a terpene indole alkaloid found in the medicinal plant ''Catharanthus roseus'' and also in the genus Voacanga (both taxa belonging to the alkaloid-rich family Apocynaceae). Tabersonine is hydroxylated at the 16 position by the enzy ...
.
See also
*
Lochnericine
Lochnericine is a major monoterpene indole alkaloid present in the roots of ''Catharanthus roseus''. It is also present in ''Tabernaemontana divaricata''.
Chemistry Synthesis
Lochnericine is formed from stereoselective epoxidation of carbons ...
References
Tryptamine alkaloids
Indolizidines
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