Veratric Acid
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Veratric acid, also known as 3,4-dimethoxybenzoic acid, is a
benzoic acid Benzoic acid is a white (or colorless) solid organic compound with the formula , whose structure consists of a benzene ring () with a carboxyl () substituent. It is the simplest aromatic carboxylic acid. The name is derived from gum benzoin, wh ...
. It is a
plant metabolite Plants are predominantly photosynthetic eukaryotes of the kingdom Plantae. Historically, the plant kingdom encompassed all living things that were not animals, and included algae and fungi; however, all current definitions of Plantae exclu ...
found in species such as '' Hypericum laricifolium'', '' Artemisia sacrorum'', and '' Zeyheria montana''.


Uses


Medical research

A 2023 study at
SRM Institute of Science and Technology SRM Institute of Science and Technology (SRMIST), formerly SRM University, is a private higher education institute deemed to be university, located in Kattankulathur, Chengalpattu (near Chennai), Tamil Nadu, India. Founded in 1985 as SRM Engin ...
suggests that veratric acid has
apoptotic Apoptosis (from grc, ἀπόπτωσις, apóptōsis, 'falling off') is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes includ ...
and
antiproliferative Cytostasis (cyto – cell; stasis – stoppage) is the inhibition of cell growth and multiplication. Cytostatic refers to a cellular component or medicine that inhibits cell division. Cytostasis is an important prerequisite for structured multic ...
effects against triple negative
breast cancer Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a re ...
cells. These effects were substantially increased when polydopamine nanoparticles were used as a sustained release drug carrier.


References

Benzoic acids Plant metabolism Botany Phytochemicals {{aromatic-stub