U.S. Route 301 (US 301) is a spur of

U.S. Route 1 U.S. Route 1 or U.S. Highway 1 (US 1) is a major north–south United States Numbered Highway that serves the East Coast of the United States. It runs from Key West, Florida, north to Fort Kent, Maine, at the Canadian border, making i ...

running through the

South Atlantic States The South Atlantic United States form one of the nine Census Bureau Divisions within the United States that are recognized by the United States Census Bureau. This region, U.S. Census Bureau Region 3, Division 5, corresponds to the South (states ...

. It runs from Biddles Corner, Delaware at

Delaware Route 1 Delaware Route 1 (DE 1) is the longest numbered state highway in the U.S. state of Delaware. The route runs from the Maryland state line in Fenwick Island, Sussex County, where the road continues south into that state as Maryland R ...

Sarasota, Florida Sarasota () is a city in Sarasota County on the Gulf Coast of the U.S. state of Florida. The area is renowned for its cultural and environmental amenities, beaches, resorts, and the Sarasota School of Architecture. The city is located in the sout ...

U.S. Route 41 U.S. Route 41, also U.S. Highway 41 (US 41), is a major north–south United States Numbered Highway that runs from Miami, Florida, to the Upper Peninsula of Michigan. Until 1949, the part in southern Florida, from Naples to Miami, ...

. It passes through the states of

Delaware Delaware ( ) is a state in the Mid-Atlantic region of the United States, bordering Maryland to its south and west; Pennsylvania to its north; and New Jersey and the Atlantic Ocean to its east. The state takes its name from the adjacent Del ...

Maryland Maryland ( ) is a state in the Mid-Atlantic region of the United States. It shares borders with Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware and the Atlantic Ocean to ...

Virginia Virginia, officially the Commonwealth of Virginia, is a state in the Mid-Atlantic and Southeastern regions of the United States, between the Atlantic Coast and the Appalachian Mountains. The geography and climate of the Commonwealth ar ...

North Carolina North Carolina () is a state in the Southeastern region of the United States. The state is the 28th largest and 9th-most populous of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, Georgia and So ...

South Carolina )''Animis opibusque parati'' ( for, , Latin, Prepared in mind and resources, links=no) , anthem = " Carolina";" South Carolina On My Mind" , Former = Province of South Carolina , seat = Columbia , LargestCity = Charleston , LargestMetro = ...

Georgia Georgia most commonly refers to: * Georgia (country), a country in the Caucasus region of Eurasia * Georgia (U.S. state), a state in the Southeast United States Georgia may also refer to: Places Historical states and entities * Related to the ...

, and

Florida Florida is a state located in the Southeastern region of the United States. Florida is bordered to the west by the Gulf of Mexico, to the northwest by Alabama, to the north by Georgia, to the east by the Bahamas and Atlantic Ocean, and to ...

. It goes through the cities of

Middletown, Delaware Middletown is a town in New Castle County, Delaware, United States. According to the 2010 Census, the population of the town is 18,871. Geography and climate Middletown is located at (39.4495560, –75.7163207) with an elevation of . According t ...

;

Annapolis, Maryland Annapolis ( ) is the capital city of the U.S. state of Maryland and the county seat of, and only incorporated city in, Anne Arundel County. Situated on the Chesapeake Bay at the mouth of the Severn River, south of Baltimore and about east o ...

;

Richmond Richmond most often refers to: * Richmond, Virginia, the capital of Virginia, United States * Richmond, London, a part of London * Richmond, North Yorkshire, a town in England * Richmond, British Columbia, a city in Canada * Richmond, California, ...

and

Petersburg, Virginia Petersburg is an independent city in the Commonwealth of Virginia in the United States. As of the 2020 census, the population was 33,458. The Bureau of Economic Analysis combines Petersburg (along with the city of Colonial Heights) with Din ...

; Rocky Mount, Wilson, and

Fayetteville, North Carolina Fayetteville () is a city in and the county seat of Cumberland County, North Carolina, United States. It is best known as the home of Fort Bragg, a major U.S. Army installation northwest of the city. Fayetteville has received the All-America C ...

;

Florence, South Carolina Florence is a city in and the county seat of Florence County, South Carolina, United States. It lies at the intersection of Interstates 20 and 95 and is the eastern terminus of the former. It is the primary city within the Florence metropolit ...

; Statesboro and

Jesup, Georgia Jesup is a city in Wayne County, Georgia, United States. The population was 9,809 at the 2020 census. The city is the county seat of Wayne County. History By February 1869, Willis Clary had begun building a two-story hotel near the junction o ...

; and

Ocala Ocala ( ) is a city in and the county seat of Marion County within the northern region of Florida, United States. As of the 2020 United States Census, the city's population was 63,591, making it the 54th most populated city in Florida. Home to ...

Zephyrhills Zephyrhills is a city in Pasco County, Florida, United States. The population was counted at 17,194 in the 2020 census. It is a suburb of the Tampa Bay Metropolitan Statistical Area. Zephyrhills is also known as the headquarters of the Zephyrhil ...

, and

. US 301 parallels

Interstate 95 Interstate 95 (I-95) is the main north–south Interstate Highway on the East Coast of the United States, running from U.S. Route 1, US Route 1 (US 1) in Miami, Miami, Florida, to the Houlton–Woodstock Border Crossing between M ...

for much of its routing through

The Carolinas The Carolinas are the U.S. states of North Carolina and South Carolina, considered collectively. They are bordered by Virginia to the north, Tennessee to the west, and Georgia to the southwest. The Atlantic Ocean is to the east. Combining Nort ...

and

including short concurrencies in

Santee, South Carolina Santee is a town in Orangeburg County along the Santee River Valley in central South Carolina, United States. It has become a resort town of note located centrally north-south along the Atlantic Seaboard of South Carolina. The region has been ru ...

and

Lumberton, North Carolina Lumberton is a city in Robeson County, North Carolina, United States. As of 2020, its population was 19,025. It is the seat of Robeson County's government. Located in southern North Carolina's Inner Banks region, Lumberton is located on the Lum ...

. It has a number of other concurrencies along its route. Originally US 301 was much shorter. Its former northern terminus was in

Baltimore, Maryland Baltimore ( , locally: or ) is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic (United States), Mid-Atlantic, and List of United States cities by popula ...

. It followed the alignment of the current

Maryland Route 3 Maryland Route 3 (MD 3), part of the Robert Crain Highway, is the designation given to the former alignment of U.S. Route 301 (US 301) from Bowie, Maryland, United States, to Baltimore. It is named for Robert Crain of Baltimore. It is uniqu ...

, portions of the Baltimore Beltway, and

Maryland Route 648 Maryland Route 648 (MD 648) is a collection of state highways in the U.S. state of Maryland. These nine highways are current or former sections of the Baltimore–Annapolis Boulevard between Annapolis, Maryland, Annapolis and Baltimore via Gl ...

. US 301 ended in Southwestern Baltimore on Monroe Street at the intersection with US 1. (Later, MD 3 was supplanted north of Millersville by

Interstate 97 Interstate 97 (I-97) is a part of the Interstate Highway System that runs entirely within Anne Arundel County, Maryland. The Interstate runs from U.S. Route 50 (US 50)/US 301 in Parole near Annapolis north to I-695 and I-895 in Brookly ...

.) It was later extended into the state of Delaware, along a different alignment that bypassed Baltimore altogether. Until 2019, the northern terminus was at

US 40 U.S. Route 40 or U.S. Highway 40 (US 40), also known as the Main Street of America, is a major east–west United States Highway traveling across the United States from the Mountain States to the Mid-Atlantic States. As with most routes wh ...

Glasgow, Delaware Glasgow is a census-designated place (CDP) in New Castle County, Delaware, United States. The population was 14,303 at the 2010 census. History La Grange and the James Stewart House are listed on the National Register of Historic Places. Geog ...

; the state of Delaware built a new tolled freeway to carry US 301, and it terminates southeast of the former terminus, at

just south of the Chesapeake & Delaware Canal. The original southern end was in Summerton, South Carolina, and it has been extended south many times to

US 41 U.S. Route 41, also U.S. Highway 41 (US 41), is a major north–south United States Numbered Highway that runs from Miami, Florida, to the Upper Peninsula of Michigan. Until 1949, the part in southern Florida, from Naples to Miami, ...

Route description

, - , FL , 266 , 428 , - , GA , 169 , 272 , - , SC , 190.3 , 306.3 , - , NC , 194 , 312.2 , - , VA , 145 , 233 , - , MD , 123.30 , 198.43 , - , DE , 11.9 , 24.03 , - , Total , 1099 , 1,769

Florida

Concurrencies in

include

US 1 U.S. Route 1 or U.S. Highway 1 (US 1) is a major north–south United States Numbered Highway that serves the East Coast of the United States. It runs from Key West, Florida, north to Fort Kent, Maine, at the Canadian border, making ...

/ 23 between Folkston (Georgia) and Callahan,

US 441 U.S. Route 441 (US 441) is a auxiliary route of U.S. Route 41. It extends from US 41 in Miami, Florida to US 25W in Rocky Top, Tennessee. Between its termini, US 441 travels through the states of Florida, Georgia, North ...

between Sparr and Belleview,

US 27 U.S. Route 27 (US 27) is a north–south United States Highway in the southern and midwestern United States. The southern terminus is at U.S. Route 1 in Florida, US 1 in Miami, Florida. The northern terminus is at Interstate 69 in India ...

between Ocala and Belleview, US 98 between Moss Town and Clinton Heights (near Dade City), and

between Palmetto and South Bradenton. The road is also shared by the DeSoto Trail south of Bushnell.

Georgia

, US 301 is signed concurrently with various

state route A state highway, state road, or state route (and the equivalent provincial highway, provincial road, or provincial route) is usually a road that is either ''numbered'' or ''maintained'' by a sub-national state or province. A road numbered by a ...

s. It uses SR 4/ SR 15 from

to Folkston, SR 23 from Folkston to Glennville, and SR 73 from Glennville to

. Large portions of US 301 in Georgia are

concurrent Concurrent means happening at the same time. Concurrency, concurrent, or concurrence may refer to: Law * Concurrence, in jurisprudence, the need to prove both ''actus reus'' and ''mens rea'' * Concurring opinion (also called a "concurrence"), a ...

with US 25. US 301 enters

from

with US 1/ US 23, also designated as SR 4/ SR 15, on a bridge over the St. Marys River. In Folkston, SR 23/ SR 121 join. US 1/US 23/SR 4/SR 15/SR 121 split to the northwest at a junction north of Folkston, leaving only US 301 and SR 23 to head north across US 82/ SR 520 at Nahunta to Jesup. At Jesup, US 301 crosses US 341/ SR 27, where US 25 turns from US 341 onto US 301, and then merges with US 84/ SR 38. The combined routes (US 25/US 84/US 301/SR 23/SR 38) cross the

Altamaha River The Altamaha River is a major river in the U.S. state of Georgia. It flows generally eastward for 137 miles (220 km) from its origin at the confluence of the Oconee River and Ocmulgee River towards the Atlantic Ocean, where it empt ...

to the junction with SR 57 in

Ludowici Ludowici is a city in Long County, Georgia, United States. The population was 1,703 at the 2010 census and an estimated 2,221 in 2018. The city is the county seat of Long County. It is a part of the Hinesville-Fort Stewart metropolitan statisti ...

. There US 84 and SR 38 continue northeast, while US 25/US 301/SR 23 turn northwest with SR 57. SR 23 and SR 57 split off to the northwest at Glennville. SR 73 begins there, taking US 25 and US 301 north from Glenville across US 280/ SR 30 at Claxton and I-16/ SR 404 to Statesboro. US 25 and US 301 meet US 80/ SR 26 and SR 67 in Statesboro. SR 67 joins south of the US 80/SR 26 crossing and then turns west with US 80/SR 26, as does US 25; US 25 and SR 67 split from US 80/SR 26 about to the west. US 301 and SR 73 continue north from Statesboro through Sylvania to the

Savannah River The Savannah River is a major river in the southeastern United States, forming most of the border between the states of South Carolina and Georgia. Two tributaries of the Savannah, the Tugaloo River and the Chattooga River, form the norther ...

and the border with

South Carolina

US 301 enters

over the

southwest of Allendale. Concurrencies include U.S. 321 in and around Ulmer, U.S. 601 between

Bamberg Bamberg (, , ; East Franconian: ''Bambärch'') is a town in Upper Franconia, Germany, on the river Regnitz close to its confluence with the river Main. The town dates back to the 9th century, when its name was derived from the nearby ' castle. C ...

and Orangeburg, then

I-95 Interstate 95 (I-95) is the main north–south Interstate Highway on the East Coast of the United States, running from US Route 1 (US 1) in Miami, Florida, to the Houlton–Woodstock Border Crossing between Maine and the Canadia ...

/ U.S. 15

Santee Santee may refer to: People * Santee Dakota, a subgroup of the Dakota people, of the U.S. Great Plains * Santee (South Carolina), a Native American people of South Carolina Places * Lake Santee, Indiana, a reservoir and census-designated place * ...

, at Exit 97 before all three move across Lake Marion. The U.S. 15-301 multiplex leaves I-95 at Exit 102, running in close proximity to I-95, but U.S. 15 breaks away at

Summerton Summerton is a town in Clarendon County, South Carolina, United States. Per the 2020 census, the population was 814. Geography Summerton is in southwestern Clarendon County at (33.605145, -80.352159). Interstate 95 passes just south of the tow ...

. Other concurrencies include U.S. 521 in

Manning Manning (a.k.a. Mannion, Manning) is a family name. Origin and meaning Manning is from an old Norse word — manningi — meaning a brave or valiant man; and one of the first forms of the name was Mannin; another cartography was Mannyg ...

, U.S. 52 between Effingham and just south of

Florence Florence ( ; it, Firenze ) is a city in Central Italy and the capital city of the Tuscany region. It is the most populated city in Tuscany, with 383,083 inhabitants in 2016, and over 1,520,000 in its metropolitan area.Bilancio demografico an ...

, U.S. 76 eastbound from east of Florence until

Pee Dee The Pee Dee is a region in the northeast corner of the U.S. state of South Carolina. It lies along the lower watershed of the Pee Dee River, which was named after the Pee Dee, a Native American tribe that historically inhabited the region. His ...

, and finally joins U.S. 501 in Latta, where they both approach the South of the Border roadside attraction complex at the interchange with

on the North Carolina-South Carolina border. Converted Motel on 301 in Wade, NC

North Carolina

US 301-501 enters

at the interchange with

where it passes the South of the Border roadside attraction complex, then closely parallels by

throughout

. Concurrencies include US 501 between Latta (South Carolina) and Rowland,

between exit 10 and exit 22 in Lumberton, I-95 BL in Fayetteville, and US 158 between Weldon and Garysburg.

Virginia

Entering Virginia just south of the community of Skippers, the route parallels

though much of the

Southside Southside or South Side may refer to: Places Australia * Southside, Queensland, a semi-rural locality in the Gympie Region Canada * South Side, Newfoundland and Labrador, a community in the St. George's Bay area on the southwest coast of Newf ...

region of Virginia, often times serving as the

frontage road A frontage road (also known as an access road, outer road, service road, feeder road, or parallel road) is a local road running parallel to a higher-speed, limited-access road. A frontage road is often used to provide access to private drivew ...

for I-95, deviating from it only in the city of Emporia, where it takes a more direct route through the center of the city. In the Richmond metro area, it passes through the historic centers of the cities of Petersburg (where it meets its parent route, U.S. 1) and Colonial Heights. Passing east of

Chester Chester is a cathedral city and the county town of Cheshire, England. It is located on the River Dee, close to the English–Welsh border. With a population of 79,645 in 2011,"2011 Census results: People and Population Profile: Chester Loca ...

, the two conjoined routes enter

and pass through the

Manchester Manchester () is a city in Greater Manchester, England. It had a population of 552,000 in 2021. It is bordered by the Cheshire Plain to the south, the Pennines to the north and east, and the neighbouring city of Salford to the west. The t ...

portion of the city along a major boulevard, crossing the James River along the

Robert E. Lee Memorial Bridge The Robert E. Lee Memorial Bridge in Richmond, Virginia carries U.S. Route 1 and U.S. Route 301 across the James River at the Fall Line. The city acquired the original bridge from Richmond Bridge Corp in 1933, and it was named the James River ...

over Belle Isle Park, and following Belvidere Street and Chamberlayne Avenue through central Richmond. At the extreme northern border of Richmond, the two routes split again, with U.S. 301 veering to the northeast past the community of

Mechanicsville, Virginia Mechanicsville is an unincorporated area and census-designated place (CDP) in Hanover County, Virginia, United States. The population was 36,348 during the 2010 census, up from 30,464 at the 2000 census. History The area was settled by Englis ...

and turning back to the north. Traveling through numerous rural areas and small communities of central Virginia, the route turns northeast along a bypass around

Bowling Green A bowling green is a finely laid, close-mown and rolled stretch of turf for playing the game of bowls. Before 1830, when Edwin Beard Budding of Thrupp, near Stroud, UK, invented the lawnmower, lawns were often kept cropped by grazing sheep ...

and passing close to

Fort A. P. Hill Fort A.P. Hill is a training and maneuver center belonging to the United States Army located near the town of Bowling Green, Virginia. The center focuses on arms training and is used by all branches of the US Armed Forces, U.S. Armed Forces. It ...

as it turns to a more east-northeasterly direction, leaving the state in Dahlgren on the

Harry W. Nice Memorial Bridge The Governor Harry W. Nice Memorial/Senator Thomas "Mac" Middleton Bridge, also known as the Potomac River Bridge, is a , two-lane continuous truss bridge that spans the Potomac River between Newburg in Charles County, Maryland and Dahlgren i ...

across the

Potomac River The Potomac River () drains the Mid-Atlantic United States, flowing from the Potomac Highlands into Chesapeake Bay. It is long,U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map. Retrieved Augus ...

Maryland

U.S. Route 301 enters Maryland along the Governor Harry W. Nice Memorial Bridge across the Potomac River from Virginia. A four-lane highway through most of the state, it is known locally as the Crain Highway and it connects several rural communities and small

exurbs An exurb (or alternately: exurban area) is an area outside the typically denser inner suburban area, at the edge of a metropolitan area, which has some economic and commuting connection to the metro area, low housing density, and growth. It sh ...

at the outer edges of the

Washington metropolitan area The Washington metropolitan area, also commonly referred to as the National Capital Region, is the metropolitan area centered on Washington, D.C. The metropolitan area includes all of Washington, D.C. and parts of the states of Maryland, Virgin ...

, connecting communities such as

La Plata La Plata () is the capital city of Buenos Aires Province, Argentina. According to the , it has a population of 654,324 and its metropolitan area, the Greater La Plata, has 787,294 inhabitants. It is located 9 kilometers (6 miles) inland from th ...

, St. Charles, Waldorf and Upper Marlboro. The route follows a generally northeast-southwest alignment until Bowie, where it leaves the Crain Highway (which continues on as

) and joins the John Hanson Highway/

U.S. Route 50 U.S. Route 50 or U.S. Highway 50 (US 50) is a major east–west route of the U.S. Highway system, stretching from Interstate 80 (I-80) in West Sacramento, California, to Maryland Route 528 (MD 528) in Ocean City, Maryland, on the Atlanti ...

, which also carries the hidden designation of I-595. The John Hanson Highway is a

freeway A controlled-access highway is a type of highway that has been designed for high-speed vehicular traffic, with all traffic flow—ingress and egress—regulated. Common English terms are freeway, motorway and expressway. Other similar terms ...

that travels roughly due east-west and carries both U.S. 50 and U.S. 301 into and through

Annapolis Annapolis ( ) is the capital city of the U.S. state of Maryland and the county seat of, and only incorporated city in, Anne Arundel County. Situated on the Chesapeake Bay at the mouth of the Severn River, south of Baltimore and about east o ...

, where the name changes to

Blue Star Memorial Highway Blue Star Memorial Highways are highways in the United States that are marked to pay tribute to the U.S. armed forces. The National Council of State Garden Clubs, now known as National Garden Clubs, Inc., started the program in 1945 after World W ...

. The freeway continues onto Maryland's Eastern Shore via the

Chesapeake Bay Bridge The Chesapeake Bay Bridge (also known locally as the Bay Bridge) is a major twin bridges, dual-span bridge in the U.S. state of Maryland. Spanning the Chesapeake Bay, it connects the state's rural Eastern Shore of Maryland, Eastern Shore regio ...

, passing across

Kent Island Kent Island is the largest island in the Chesapeake Bay and a historic place in Maryland. To the east, a narrow channel known as the Kent Narrows barely separates the island from the Delmarva Peninsula, and on the other side, the island is sep ...

. At the end of the freeway, the two routes split, each following a four-lane divided road through the eastern shore, with U.S. 50 going generally south and U.S. 301 going generally north. The four lane divided road continues generally northeast through the rural Eastern Shore region before crossing into Delaware and becoming a freeway.

Delaware

US 301 in Delaware is a four-lane tolled freeway that enters the state from Maryland and heads northeast past Middletown before coming to its northern terminus at an interchange with

in Biddles Corner, south of the

Senator William V. Roth Jr. Bridge The Senator William V. Roth Jr. Bridge (originally the Chesapeake & Delaware Canal Bridge and also referred to as the Roth Bridge) is a concrete and steel cable-stayed bridge that spans the Chesapeake & Delaware Canal near St. Georges, Delaware. ...

over the Chesapeake & Delaware Canal in St. Georges. The new alignment opened in January 2019 and replaces the former routing that ended at U.S. Route 40 in

Glasgow Glasgow ( ; sco, Glesca or ; gd, Glaschu ) is the most populous city in Scotland and the fourth-most populous city in the United Kingdom, as well as being the 27th largest city by population in Europe. In 2020, it had an estimated popul ...

History

US 301 was established in 1932 as a replacement of the piece of US 17-1 north of Wilson and the whole of US 217. Thus US 301 initially ran from US 17 (now US 76) at

Pee Dee, South Carolina The Pee Dee is a region in the northeast corner of the U.S. state of South Carolina. It lies along the lower watershed of the Pee Dee River, which was named after the Pedee people, Pee Dee, a Native Americans in the United States, Native American ...

northeast through

Dillon Dillon may refer to: People *Dillon (surname) * Dillon (given name) * Dillon (singer) (born 1988), Brazilian singer *Viscount Dillon, a title in the Peerage of Ireland Places Canada *Dillon, Saskatchewan United States *Dillon Beach, Californi ...

, Lumberton, Fayetteville, Dunn, Smithfield, Wilson, Rocky Mount, and Emporia, ending at US 1 in

. This entire route is now paralleled by

. US 301 was at one time alternately referred to as Federal Route No. 301 early in its existence. In 1935, US 301 was extended southwest to

US 15 U.S. Route 15 (US 15) is a -long United States highway, designated along South Carolina, North Carolina, Virginia, Maryland, Pennsylvania, and New York. The route is signed north–south, from U.S. Route 17 Alternate in Walterboro, South Car ...

. This extension took it west on US 76 (formerly US 17) to

and south on US 52 (also formerly US 17) to Effingham. There it split to the southwest, running along what had been SC 4 via

to Summerton.The Highways of South Carolina
US 301
/ref> This again runs parallel to

. The next extension was to the north in late 1940, coinciding with the opening of the

Potomac River Bridge The Governor Harry W. Nice Memorial/Senator Thomas "Mac" Middleton Bridge, also known as the Potomac River Bridge, is a , two-lane continuous truss bridge that spans the Potomac River between Newburg, Maryland, Newburg in Charles County, Marylan ...

. US 301 was extended north along US 1 from Petersburg to

, then north on SR 2 to

, and northeast on SR 207 to the bridge. In Maryland it continued along the new alignment off the bridge to

Newburg, Maryland Newburg is an unincorporated community in Charles County, Maryland, United States. Newburg has two stores, a lodge hall, and a fire department, as well as Piccowaxen Middle School and Dr. Thomas L. Higdon Elementary, both serving the entire Cob ...

, and then replaced MD 3 all the way to US 1 in

. In the late 1940s, US 301 was extended again, south all the way to

Tampa, Florida Tampa () is a city on the Gulf Coast of the United States, Gulf Coast of the U.S. state of Florida. The city's borders include the north shore of Tampa Bay and the east shore of Old Tampa Bay. Tampa is the largest city in the Tampa Bay area and ...

. In South Carolina it ran along

southwest to

and replaced SC 4 west to

Orangeburg, South Carolina Orangeburg, also known as ''The Garden City'', is the principal city in and the county seat of Orangeburg County, South Carolina, United States. The population of the city was 13,964 according to the 2010 United States Census and declined to 12 ...

. From Orangeburg, US 301 ran southwest with US 601 to

Bamberg, South Carolina Bamberg is a city in and the county seat of Bamberg County, South Carolina, United States. The population was 3,607 at the 2010 census. History Bamberg is named after early resident William Seaborn Bamberg. Members of the Bamberg family contin ...

, replaced SC 33 to

Ulmer, South Carolina Ulmer is a town in Allendale County, South Carolina, United States. The population was 88 at the 2010 census. History The Williams House was added to the National Register of Historic Places in 1999. Geography Ulmer is located at (33.096652, ...

, replaced SC 508 to Allendale, South Carolina, and replaced SC 73 to the

state line. In Georgia, US 301 was marked along SR 73 to Glennville, Georgia, SR 23 to Folkston, and SR 4 to the border with

, numbers that it still has today. In Florida it ran along SR 15 to

Callahan Callahan may refer to: *Callahan (surname) Fictional characters *Father Callahan, in Stephen King novels *Harry Callahan (character), in ''Dirty Harry'' movies * Jack Callahan (''Neighbours''), from the Australian soap opera ''Neighbours'' *Mik ...

, SR 200 to

, SR 25/ SR 500 to

Belleview Belleview can refer to: * Belleview (Middletown, Delaware), listed on the National Register of Historic Places listings in southern New Castle County, Delaware * Belleview (Harrods Creek, Kentucky), listed on the National Register of Historic Pl ...

, SR 35 to

Dade City Dade City is a city in and the county seat of Pasco County, Florida, United States. It is located in the Tampa Bay Area. The population was 6,437 at the 2010 census. Dade City is popular with tourists for its antique stores, restaurants, and h ...

, SR 39 to

, and State Road 41 to

Rand McNally Rand McNally is an American technology and publishing company that provides mapping, software and hardware for consumer electronics, commercial transportation and education markets. The company is headquartered in Chicago, with a distribution c ...

, Florida, 1947, distributed by

Sinclair Oil Sinclair Oil Corporation was an American petroleum corporation, founded by Harry F. Sinclair on May 1, 1916, the Sinclair Oil and Refining Corporation combined, amalgamated, the assets of 11 small petroleum companies. Originally a New York cor ...

As with Georgia, these State Road numbers still exist. The final extension to the south was made in the early 1950s. US 301 was realigned to turn east on

U.S. Route 92 U.S. Route 92 or U.S. Highway 92 (US 92) is a 181-mile (291 km.) U.S. Route entirely in the U.S. state of Florida. The western terminus is at U.S. Route 19 Alternate (Florida), US 19 Alt. and Florida State Road 687, SR 687 in downtown St. Pe ...

/ SR 600 in northern Tampa and south on SR 43; SR 43 was later extended north to meet SR 41 at

Thonotosassa Thonotosassa is a census-designated place (CDP) in Hillsborough County, Florida, United States. The population was 15,238 at the 2020 census, up from 13,014 at the 2010 census. History The name "Thonotosassa" comes from the Seminole- Creek w ...

. This was done at the same time as US 541 was eliminated and US 41 was moved onto the former US 541 south of Tampa; US 301 ran along what had been US 41. This extension took US 301 south to Palmetto along SR 43/former US 41, south on SR 45/US 41 over the

Manatee River The Manatee River is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map, accessed April 18, 2011 river in Manatee County, Florida. The river forms in the northeastern corner of Manatee County an ...

into

Bradenton, Florida Bradenton ( ) is a city in and the county seat of Manatee County, Florida, Manatee County, Florida, United States. As of the 2020 United States Census, 2020 census, the city's population is 55,698. History Late 18th and early 19th centuries ...

(replaced 1957 by a new bridge to the east on SR 55), and south on SR 683 to end at SR 45/US 41 in

Sarasota Sarasota () is a city in Sarasota County on the Gulf Coast of the U.S. state of Florida. The area is renowned for its cultural and environmental amenities, beaches, resorts, and the Sarasota School of Architecture. The city is located in the sou ...

. In 1960, US 301 was extended to its greatest extent,

to Farnhurst. The part from near Bowie north to

Baltimore Baltimore ( , locally: or ) is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic (United States), Mid-Atlantic, and List of United States cities by popula ...

reverted to MD 3, and US 301 was extended east along US 50 from near Bowie over the

to Queenstown. There it split to the northeast, replacing MD 71 to the

state line. In Delaware, it continued

with DE 71 to Middletown. There it split into a

one-way pair A one-way pair, one-way couple, or couplet refers to that portion of a bi-directional traffic facilitysuch as a road, bus, streetcar, or light rail linewhere its opposing flows exist as two independent and roughly parallel facilities. Descriptio ...

on two two-way roads. US 301 northbound turned east at Middletown along DE 299, then running north on US 13 to its end at Farnhurst at

I-295 Interstate 295 is the designation for several Interstate Highways in the United States: *Interstate 295 (Delaware–Pennsylvania), a bypass of Philadelphia, Pennsylvania * Interstate 295 (Florida), a beltway around central Jacksonville * Interstate ...

- the

Delaware Memorial Bridge The Delaware Memorial Bridge is a dual-span suspension bridge crossing the Delaware River. The toll bridges carry Interstate 295 and U.S. Route 40 and is also the link between Delaware and New Jersey. The bridge was designed by the firm kn ...

approach. Southbound US 301 began at the same place, but only used US 13 to the DE 71 junction near Red Lion. From there it followed DE 71 all the way to Maryland, rejoining northbound at Middletown. In the early 1970s, the northbound alignment was modified, continuing north on Middletown with DE 71 across the Chesapeake and Delaware Canal on the Summit Bridge. After crossing the canal it continued north on DE 896 to

, where it turned east with US 40 to its merge with US 13 at State Road. In the mid-1980s, both directions were moved to run east from Mount Pleasant to US 13. Then in 1992, AASHTO approved relocating both directions to the path northbound had followed, joining US 40 at Glasgow. Signage currently now indicates that US 301 ends there, but on November 14, 2006, the

Delaware Department of Transportation The Delaware Department of Transportation (DelDOT) is an agency of the U.S. state of Delaware. The Secretary of Transportation is Nicole Majeski. The agency was established in 1917 and has its headquarters in Dover. The department's responsibil ...

(DelDOT) announced that a new four-lane US 301 bypass will be built. The bypass, which had been proposed since the 1950s, would go west of Middletown, alleviating traffic conditions in state's fourth most populous town, and then travel in a northeasterly direction, intersecting the current DE 896 near Boyds Corner and then terminate at DE 1 near the highway's Biddles Corner toll plaza. A spur route, also following the old 1960s highway route, will connect US 301 with the four-lane Summit Bridge just south of Glasgow. When built, the road, like Delaware Route 1 and

, will charge a toll to cover the costs of building the new bypass, which is heavily used by trucks between

Philadelphia Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Sinc ...

and the

Washington, D.C. ) , image_skyline = , image_caption = Clockwise from top left: the Washington Monument and Lincoln Memorial on the National Mall, United States Capitol, Logan Circle, Jefferson Memorial, White House, Adams Morgan, ...

metro areas. This bypass opened to traffic on January 10, 2019. According to one source, US 301 had been known as "Tobacco Trail" prior to its renaming in 1960 to "The Miss Universe Highway". Prior to 2019, US 301 in Delaware started at the intersection of U.S. 40 and

Delaware Route 896 Delaware Route 896 (DE 896) is a state highway located in New Castle County, Delaware. The route runs from U.S. Route 13 (US 13) in Boyds Corner north to the Maryland border northwest of Newark, where the road becomes unsi ...

. The highway was cosigned with DE 896, picking up

Delaware Route 71 Delaware Route 71 (DE 71) is a state highway in New Castle County, Delaware. The route runs from U.S. Route 13 (US 13) south of Townsend north to another intersection with US 13 in Tybouts Corner, traveling to the west ...

only three miles south of U.S. 40. Running parallel to

US 13 U.S. Route 13 (US 13) is a north–south U.S. highway established in 1926 that runs for from Interstate 95 (I-95) just north of Fayetteville, North Carolina to US 1 in the northeastern suburbs of Philadelphia, Pennsylvania, in Morrisville ...

and

, the highway crossed the Chesapeake and Delaware Canal on the four-lane Summit Bridge. At Mount Pleasant, DE 896 headed east to intersect U.S. 13 at Boyd's Corner, while DE 71 continued to be cosigned with U.S. 301 until the road reached Middletown. U.S. 301 continued alone until it picked up two other roads,

Delaware Route 15 Delaware Route 15 (DE 15) is a state highway in the U.S. state of Delaware. The route runs from DE 14 west of Milford in Kent County north to DE 71/ DE 896 in Summit Bridge, New Castle County, just south of the Summ ...

and

Delaware Route 299 Delaware Route 299 (DE 299) is a state highway in New Castle County, Delaware. It runs from Maryland Route 282 (MD 282) at the Maryland state line east of Warwick, Maryland to DE 9 in Mathews Corners, traveling throug ...

, which followed the highway to near the

state line. On November 14, 2006, DelDOT announced that a new four-lane bypass around Middletown will reroute US 301 west of Middletown, with the road directly connecting to DE 1 in Biddles Corner. This bypass opened to traffic on January 10, 2019.

U.S. Route 217

U.S. Route 217 (US 217) was an original US highway, established in 1926. It traversed from US 17, in

, to US 17-1/ NC 40, south of

Wilson, North Carolina Wilson is a city in and the county seat of Wilson County, North Carolina, United States. Located approximately east of the capital city of Raleigh, it is served by the interchange of Interstate 95 and U.S. Route 264. Wilson had an estimated p ...

. Its routing connected the cities of

, Lumberton, Fayetteville, Dunn, and Smithfield. In 1932, the entire route was renumbered as part of US 301.

Major intersections

;Florida : in

: on the

Bradenton Bradenton ( ) is a city in and the county seat of Manatee County, Florida, United States. As of the 2020 census, the city's population is 55,698. History Late 18th and early 19th centuries A settlement established by Maroons or escaped sl ...

–West Samoset, Florida, West Samoset city line. The highways travel concurrently to Palmetto. : in Ellenton, Florida, Ellenton : in Palm River-Clair Mel, Florida, Palm River-Clair Mel : in East Lake-Orient Park, Florida, East Lake-Orient Park : south of

. The highways travel concurrently to Lacoochee, Florida, Lacoochee. : in

. US 27/US 301 travels concurrently to

. US 301/US 441 travels concurrently to southeast of Reddick, Florida, Reddick. : south-southwest of Baldwin, Florida, Baldwin : in Baldwin. The highways travel concurrently through Baldwin. : in

. The highways travel concurrently to Homeland, Georgia. ;Georgia : in Nahunta : in Jesup. US 25/US 301 travels concurrently to Statesboro. : in Jesup. The highways travel concurrently to

. : in Claxton : south-southeast of Register, Georgia, Register : in Statesboro ;South Carolina : in Allendale. The highways travel concurrently through Allendale. : in Ulmer, South Carolina, Ulmer. The highways travel concurrently to northeast of Ulmer. : in

. The highways travel concurrently to Orangeburg. : in Bamberg : in Orangeburg : southeast of Wilkinson Heights, South Carolina, Wilkinson Heights : south-southwest of Elloree, South Carolina, Elloree : south-southwest of

. The highways travel concurrently to

. : south-southeast of Santee. The highways travel concurrently to south-southwest of Summerton. : southwest of

: in Manning. The highways travel concurrently to north-northeast of Manning. : in Turbeville, South Carolina, Turbeville. The highways travel concurrently through Turbeville. : in Effingham. The highways travel concurrently to

. : east of Florence. The highways travel concurrently to

. : south of Latta. The highways travel concurrently to Rowland, North Carolina. ;South Carolina–North Carolina : at the

–

state line at South of the Border ;North Carolina : east of Raynham, North Carolina, Raynham. The highways travel concurrently to Lumberton. : southwest of Lumberton : north of Lumberton : north of St. Pauls, North Carolina, St. Pauls : in Dunn : northeast of Four Oaks, North Carolina, Four Oaks : in Selma, North Carolina, Selma : southwest of Kenly, North Carolina, Kenly : south-southwest of Wilson : south-southwest of Wilson : south-southwest of Wilson : in Rocky Mount : in Weldon, North Carolina, Weldon. The highways travel concurrently to Garysburg, North Carolina, Garysburg. ;Virginia : in Emporia : south of Jarratt, Virginia, Jarratt : in Carson, Virginia, Carson : in Templeton, Virginia, Templeton : south-southeast of Petersburg : in Petersburg : in Petersburg. The highways travel concurrently to

. : in Richmond : in Richmond : in Richmond : in Richmond : in Chamberlayne, Virginia, Chamberlayne : in Mechanicsville, Virginia, Mechanicsville : in Port Royal Cross Roads, Virginia, Port Royal Cross Roads ;Maryland : in Bowie. I-595/US 301 shares a hidden concurrency to Parole, Maryland, Parole. US 50/US 301 travels concurrently to Queenstown. : in Parole ;Delaware : in Biddles Corner

Special routes

There are currently eight active special routes along US 301: * U.S. Route 301 Truck (Dade City, Florida), US 301 Truck – Dade City, Florida *US 301 Alternate - Starke, FL *US 301 Alternate - Baldwin, Florida, Baldwin, FL * U.S. Route 301 Bypass (Statesboro, Georgia), US 301 Bypass – Statesboro, Georgia * U.S. Route 301 Business (Rocky Mount, North Carolina), US 301 Business – Rocky Mount, North Carolina * U.S. Route 301 Business (Halifax, North Carolina), US 301 Business – Halifax, North Carolina * U.S. Route 301 Alternate (Petersburg, Virginia), US 301 Alternate –

* U.S. Route 301 Business (Bowling Green, Virginia), US 301 Business – Bowling Green, Virginia

References

External links

*
Endpoints of U.S. highway 301Federal Highway Administration Home PageAAA Speed Trap Billboards
{{Authority control U.S. Route 301, United States Numbered Highway System, 01-3 Interstate 95, 301 U.S. Route 1, 3