Todd Golub
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Todd R. Golub is a Professor of Pediatrics at the
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
, the Charles A. Dana Investigator in Human Cancer Genetics at the
Dana–Farber Cancer Institute Dana–Farber Cancer Institute is a comprehensive cancer treatment and research institution in Boston, Massachusetts. Dana–Farber is the founding member of Dana–Farber/Harvard Cancer Center, Harvard's Comprehensive Cancer Center designated b ...
, and th
Director
and a founding member of the
Broad Institute The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: , pronunciation respelling: ), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, Cambridge, Massachusetts, U ...
of
MIT The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the m ...
and
Harvard Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
. He is a world leader in applying genomic tools (such as
DNA microarrays A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to ...
) to cancer research, having made important discoveries in the molecular basis of childhood
leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ' ...
. He graduated from
New Trier High School New Trier High School (, also known as New Trier Township High School or NTHS) is a public four-year high school, with its main campus for sophomores through seniors located in Winnetka, Illinois, United States, and a campus in Northfield, Illinoi ...
in 1981 and then received his B.A. in 1985 from
Carleton College Carleton College ( ) is a private liberal arts college in Northfield, Minnesota. Founded in 1866, it had 2,105 undergraduate students and 269 faculty members in fall 2016. The 200-acre main campus is between Northfield and the 800-acre Cowling ...
and M.D. in 1989 from the
University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the b ...
's
Pritzker School of Medicine The Pritzker School of Medicine is the Doctor of Medicine, M.D.-granting unit of the Biological Sciences Division of the University of Chicago. It is located on the university's main campus in the historic Hyde Park, Chicago, Hyde Park neighbo ...
.


Awards

*
Discover Magazine ''Discover'' is an American general audience science magazine launched in October 1980 by Time Inc. It has been owned by Kalmbach Publishing since 2010. History Founding ''Discover'' was created primarily through the efforts of ''Time'' mag ...
's Inventor of the Year (Health Category), 2000 *
Daland Prize Daland may refer to: People * Jesper Daland (born 2000), Norwegian football player * Morten Daland, Norwegian handball player * Peter Daland (1921–2014), American swimming coach Places * Daland, Iran Other

* Huff-Daland, American aircraft m ...
of the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
, 2001 * Cornelius Rhoads Memorial Prize,
American Association for Cancer Research The American Association for Cancer Research (AACR) is the world's oldest and largest professional association related to cancer research. Based in Philadelphia, the AACR focuses on all aspects of cancer research, including basic, clinical, and t ...
, 2002 *
Paul Marks Prize for Cancer Research The Paul Marks Prize for Cancer Research is awarded by the Memorial Sloan Kettering Cancer Center to recognize cancer researchers who are making significant contributions to the understanding of cancer or are improving the treatment of the disease t ...
, 2007 * American Society of Hematology Scholar Award, 1999


Selected publications

Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, Bernstein BE, Drier Y, Fonseca R, Gabriel SB, Hofmeister CC, Jagannath S, Jakubowiak AJ, Krishnan A, Levy J, Liefeld T, Lonial S, Mahan S, Mfuko B, Monti S, Perkins LM, Onofrio R, Pugh TJ, Rajkumar SV, Ramos AH, Siegel DS, Sivachenko A, Stewart AK, Trudel S, Vij R, Voet D, Winckler W, Zimmerman T, Carpten J, Trent J, Hahn WC, Garraway LA, Meyerson M, Lander ES, Getz G, Golub TR. Initial genome sequencing and analysis of multiple myeloma. Nature. 2011 Mar 24;471(7339):467-72. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR. MicroRNA expression profiles classify human cancers. Nature. 2005 Jun 9;435(7043):834-8. Stegmaier K, Ross KN, Colavito SA, O'Malley S, Stockwell BR, Golub TR. Gene expression-based high-throughput screening (GE-HTS) and application to leukemia differentiation. Nat Genet 2004;36:257-63. Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, Coller H, Loh ML, Downing JR, Caligiuri MA, Bloomfield CD, Lander ES. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science. 1999 Oct 15;286(5439):531-7.


See also

*
Bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
* ''Cancer'' (2015 PBS film) *
Genomics Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...
*
History of cancer The history of cancer describes the development of the field of oncology and its role in the history of medicine. Early diagnosis The earliest known descriptions of cancer appear in several papyri from Ancient Egypt. The Edwin Smith Papyrus was ...
*
History of cancer chemotherapy The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. The targeted therapy revolution has arrived, but many of the principles and limitations of chemotherapy discovered by the ...
* '' The Emperor of All Maladies: A Biography of Cancer''


References


External links


Dr. Golub's Contact Page at Harvard Medical School
{{DEFAULTSORT:Golub, Todd R 1962 births Living people Jewish American scientists Massachusetts Institute of Technology faculty New Trier High School alumni Carleton College alumni Pritzker School of Medicine alumni Harvard Medical School faculty Howard Hughes Medical Investigators 21st-century American Jews Members of the National Academy of Medicine