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A thyroidectomy is an operation that involves the surgical removal of all or part of the
thyroid gland The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans it is in the neck and consists of two connected lobe (anatomy), lobes. The lower two thirds of the lobes are connected by a thin band of Connective tissue, tissue cal ...
. In
general surgery General surgery is a surgical specialty that focuses on alimentary canal and abdominal contents including the esophagus, stomach, small intestine, large intestine, liver, pancreas, gallbladder, appendix and bile ducts, and often the thyroid ...
, endocrine or head and neck surgeons often perform a thyroidectomy when a patient has thyroid
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
or some other condition of the thyroid
gland In animals, a gland is a group of cells in an animal's body that synthesizes substances (such as hormones) for release into the bloodstream (endocrine gland) or into cavities inside the body or its outer surface (exocrine gland). Structure De ...
(such as
hyperthyroidism Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormones by the thyroid gland. Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism ...
) or goiter. Other indications for surgery include cosmetic (very enlarged thyroid), or symptomatic obstruction (causing difficulties in swallowing or breathing). Thyroidectomy is a common surgical procedure that has several potential complications or sequelae including: temporary or permanent change in voice, temporary or permanently low calcium, need for lifelong thyroid hormone replacement, bleeding, infection, and the remote possibility of airway obstruction due to bilateral vocal cord paralysis. Complications are uncommon when the procedure is performed by an experienced surgeon. The thyroid produces several
hormone A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and behavior. Hormones are required ...
s, such as thyroxine (T4),
triiodothyronine Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. Production of T3 and its prohormone thyroxine ( ...
(T3), and
calcitonin Calcitonin is a 32 amino acid peptide hormone secreted by parafollicular cells (also known as C cells) of the thyroid (or endostyle) in humans and other chordates. in the ultimopharyngeal body. It acts to reduce blood calcium (Ca2+), opposing the ...
. After the removal of a thyroid, patients usually take a prescribed oral synthetic thyroid hormone—
levothyroxine Levothyroxine, also known as -thyroxine, is a manufactured form of the thyroid hormone thyroxine (T4). It is used to treat hypothyroidism, thyroid hormone deficiency (hypothyroidism), including a severe form known as myxedema coma. It may also ...
(Synthroid)—to prevent
hypothyroidism Hypothyroidism (also called ''underactive thyroid'', ''low thyroid'' or ''hypothyreosis'') is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormone. It can cause a number of symptoms, such as po ...
. Less extreme variants of thyroidectomy include: * Hemithyroidectomy (or unilateral lobectomy): removing only half of the thyroid * Isthmectomy: removing the band of tissue (or isthmus) connecting the two lobes of the thyroid A thyroidectomy should not be confused with a
thyroidotomy :''Thyrotomy may also refer to the cutting or biopsy the thyroid gland.'' Thyrotomy (also called thyroidotomy, median laryngotomy, laryngofissure or thyrofissure) is an incision of the larynx through the thyroid cartilage. See also *Laryngotomy *C ...
(
thyrotomy :''Thyrotomy may also refer to the cutting or biopsy the thyroid gland.'' Thyrotomy (also called thyroidotomy, median laryngotomy, laryngofissure or thyrofissure) is an incision of the larynx through the thyroid cartilage. See also * Laryngotomy ...
), which is a cutting into (''‑otomy'') the thyroid, not a removal ('' ‑ectomy'', literally “out-cutting”) of it. A thyroidotomy can be performed to get access for a
median laryngotomy :''Thyrotomy may also refer to the cutting or biopsy the thyroid gland.'' Thyrotomy (also called thyroidotomy, median laryngotomy, laryngofissure or thyrofissure) is an incision of the larynx through the thyroid cartilage. See also *Laryngotomy *C ...
, or to perform a
biopsy A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist. The process involves extraction of sample cells or tissues for examination to determine the presence or extent of a diseas ...
. (Although technically a biopsy involves removing some tissue, it is more frequently categorized as an ''‑otomy'' than an ''‑ectomy'' because the volume of tissue removed is minuscule.) Traditionally, the thyroid has been removed through a neck incision that leaves a permanent scar. More recently,
minimally invasive Minimally invasive procedures (also known as minimally invasive surgeries) encompass surgical techniques that limit the size of incisions needed, thereby reducing wound healing time, associated pain, and risk of infection. Surgery by definition ...
and "scarless" approaches such as transoral thyroidectomy have become popular in some parts of the world. In the United States, over 100,000 procedures are performed yearly as it is a common procedure.


Uses

Thyroidectomy is used in the treatment of: *
Thyroid cancer Thyroid cancer is cancer that develops from the tissues of the thyroid gland. It is a disease in which cells grow abnormally and have the potential to spread to other parts of the body. Symptoms can include swelling or a lump in the neck. C ...
* Toxic
thyroid nodule Thyroid nodules are nodules (raised areas of tissue or fluid) which commonly arise within an otherwise normal thyroid gland. They may be hyperplastic or tumorous, but only a small percentage of thyroid tumors are malignant. Small, asymptomatic n ...
(produces too much thyroid hormone) * Multinodular goiter (enlarged thyroid gland with many nodules), especially if there is compression of nearby structures *
Graves' disease Graves' disease (german: Morbus Basedow), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism. It also often results in an enlarged thyr ...
, especially if there is exophthalmos (bulging eyes) * Thyroid nodule, if
fine needle aspirate Fine-needle aspiration (FNA) is a diagnostic procedure used to investigate lumps or masses. In this technique, a thin (23–25 gauge (0.52 to 0.64 mm outer diameter)), hollow needle is inserted into the mass for sampling of cells that, aft ...
(FNA) results are unclear


Types

:::::::::::::* ''Hemithyroidectomy'' — Entire isthmus is removed along with 1 lobe. Done in benign diseases of only 1 lobe. :::::::::::::* ''Subtotal thyroidectomy'' — Removal of majority of both lobes leaving behind 4-5 grams (equivalent to the size of a normal thyroid gland) of thyroid tissue on one or both sides—this used to be the most common operation for multinodular goitre. :::::::::::::* ''Partial thyroidectomy'' —Removal of gland in front of trachea after mobilization. Done in nontoxic MNG. Its role is controversial. :::::::::::::* ''Near total thyroidectomy'' — Both lobes are removed except for a small amount of thyroid tissue (on one or both sides) in the vicinity of the recurrent laryngeal nerve entry point and the superior parathyroid gland. :::::::::::::* ''Total thyroidectomy'' — Entire gland is removed. Done in cases of papillary or follicular carcinoma of thyroid, medullary carcinoma of thyroid. This is now also the most common operation for multinodular goitre. :::::::::::::* ''Hartley Dunhill operation'' — Removal of 1 entire lateral lobe with isthmus and partial/subtotal removal of opposite lateral lobe. Done in nontoxic MNG.


Complications

*
Hypothyroidism Hypothyroidism (also called ''underactive thyroid'', ''low thyroid'' or ''hypothyreosis'') is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormone. It can cause a number of symptoms, such as po ...
in up to 50% of patients after ten years. * Laryngeal nerve injury in about 1% of patients, in particular the
recurrent laryngeal nerve The recurrent laryngeal nerve (RLN) is a branch of the vagus nerve (cranial nerve X) that supplies all the intrinsic muscles of the larynx, with the exception of the cricothyroid muscles. There are two recurrent laryngeal nerves, right and le ...
: Unilateral damage results in a hoarse voice. Bilateral damage presents as laryngeal obstruction after surgery and can be a surgical emergency: an emergency
tracheostomy Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the Vertebrate trachea, trache ...
may be needed. Recurrent Laryngeal nerve injury may occur during the ligature of the inferior thyroid artery. * Hypoparathyroidism temporary (transient) in many patients, but permanent in about 1 to 4% of patients * Anesthetic complications *
Infection An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dise ...
(at about a 2% rate. Drainage is an important part of treatment.), possibly an increased risk with chronic pre-operative steroid use. * Stitch
granuloma A granuloma is an aggregation of macrophages that forms in response to chronic inflammation. This occurs when the immune system attempts to isolate foreign substances that it is otherwise unable to eliminate. Such substances include infectious ...
*
Chyle Chyle (from the Ancient Greek, Greek word χυλός ''chylos'', "juice") is a milky bodily fluid consisting of lymph and emulsified fats, or free fatty acids (FFAs). It is formed in the small intestine during digestion of fatty foods, and taken ...
leak * Haemorrhage/
Hematoma A hematoma, also spelled haematoma, or blood suffusion is a localized bleeding outside of blood vessels, due to either disease or trauma including injury or surgery and may involve blood continuing to seep from broken capillary, capillaries. A he ...
(This may compress the airway, becoming life-threatening.) * Removal or devascularization of the parathyroids


History

Al-Zahrawi Abū al-Qāsim Khalaf ibn al-'Abbās al-Zahrāwī al-Ansari ( ar, أبو القاسم خلف بن العباس الزهراوي;‎ 936–1013), popularly known as al-Zahrawi (), Latinised as Albucasis (from Arabic ''Abū al-Qāsim''), was ...
, a tenth century
Arab The Arabs (singular: Arab; singular ar, عَرَبِيٌّ, DIN 31635: , , plural ar, عَرَب, DIN 31635: , Arabic pronunciation: ), also known as the Arab people, are an ethnic group mainly inhabiting the Arab world in Western Asia, ...
physician, sometimes referred to as the "Father of surgery", is credited with the performance of the first thyroidectomy.Ignjatovic M: Overview of the history of thyroid surgery. Acta Chir Iugosl 2003; 50: 9–36.


See also

* List of surgeries by type


References


External links


Early postoperative scar images


From the Patient Education Institute {{Endocrine system intervention Surgical oncology Surgical removal procedures Thyroid disease Endocrine surgery Thyroidological methods