Thomas Dao
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Ling Yuan "Thomas" Dao (April 27, 1921 – July 16, 2009) was a
Chinese American Chinese Americans are Americans of Han Chinese ancestry. Chinese Americans constitute a subgroup of East Asian Americans which also constitute a subgroup of Asian Americans. Many Chinese Americans along with their ancestors trace lineage from ...
physician and specialist in breast cancer, its causes and treatment, who was one of the earliest proponents of minimalist alternatives to
radical mastectomy Radical mastectomy is a surgical procedure involving the removal of breast, underlying chest muscle (including pectoralis major and pectoralis minor), and lymph nodes of the axilla as a treatment for breast cancer. Breast cancer is the most comm ...
as a treatment option for
breast cancer Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a re ...
, in addition to advocacy of
breast self-examination Breast self-examination (BSE) is a screening method used in an attempt to detect early breast cancer. The method involves the woman herself looking at and feeling each breast for possible lumps, distortions or swelling. BSE was once promoted hea ...
and
mammography Mammography (also called mastography) is the process of using low-energy X-rays (usually around 30 kVp) to examine the human breast for diagnosis and screening. The goal of mammography is the early detection of breast cancer, typically through d ...
as means to detect breast cancer as early as possible.Staff
"Dr. Thomas L. Dao, Roswell Park cancer researcher"
''
The Buffalo News ''The Buffalo News'' is the daily newspaper of the Buffalo–Niagara Falls metropolitan area, located in downtown Buffalo, New York. It recently sold its headquarters to Uniland Development Corp. It was for decades the only paper fully owned by W ...
'', July 21, 2009. Accessed July 26, 2009.


Early life and education

Dao was born on April 27, 1921, in
Suzhou Suzhou (; ; Suzhounese: ''sou¹ tseu¹'' , Mandarin: ), alternately romanized as Soochow, is a major city in southern Jiangsu province, East China. Suzhou is the largest city in Jiangsu, and a major economic center and focal point of trade ...
,
China China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and ...
, where his father was a lawyer. There he went to Soochow University, where he received his undergraduate degree. He attended
Saint John's University St John's University may refer to: *St. John's University (New York City) ** St. John's University School of Law **St. John's University (Italy) - Overseas Campus * College of Saint Benedict and Saint John's University, St. Joseph, Minnesota and C ...
in
Shanghai Shanghai (; , , Standard Mandarin pronunciation: ) is one of the four direct-administered municipalities of the People's Republic of China (PRC). The city is located on the southern estuary of the Yangtze River, with the Huangpu River flow ...
, where he earned his master's degree and received his medical training, and went to the United States in 1949 for a
residency Residency may refer to: * Domicile (law), the act of establishing or maintaining a residence in a given place ** Permanent residency, indefinite residence within a country despite not having citizenship * Residency (medicine), a stage of postgrad ...
in surgery. He had planned to return to China, but chose to reside in the U.S. after
Mao Zedong Mao Zedong pronounced ; also romanised traditionally as Mao Tse-tung. (26 December 1893 – 9 September 1976), also known as Chairman Mao, was a Chinese communist revolutionary who was the founder of the People's Republic of China (PRC) ...
rose to power. Once he settled in the United States, he adopted the name "Thomas".Hevesi, Dennis
"Dr. Thomas Dao, Expert on Treatment of Breast Cancer, Dies at 88"
''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
'', July 25, 2009. Accessed July 26, 2009.


Medical career

He worked for future
Nobel Prize The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfr ...
winner Dr.
Charles Brenton Huggins Charles Brenton Huggins (September 22, 1901 – January 12, 1997) was a Canadian-American physician, physiologist and cancer researcher at the University of Chicago specializing in prostate cancer. He was awarded the 1966 Nobel Prize for Physio ...
at the
University of Chicago Medical School The Pritzker School of Medicine is the M.D.-granting unit of the Biological Sciences Division of the University of Chicago. It is located on the university's main campus in the historic Hyde Park neighborhood of Chicago and matriculated its f ...
as a researcher assisting in Huggins' studies of how
hormone A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and behavior. Hormones are required ...
s relate to cancer in humans. There, Dao participated in research studies of treating advanced cases of breast cancer by surgical removal of the
adrenal gland The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer cortex which ...
and
ovaries The ovary is an organ in the female reproductive system that produces an ovum. When released, this travels down the fallopian tube into the uterus, where it may become fertilized by a sperm. There is an ovary () found on each side of the body. T ...
. In 1951, he became an instructor in surgery at the medical school, and was named assistant professor of surgery in 1954. Starting in 1957, he served at
Roswell Park Comprehensive Cancer Center Roswell Park Comprehensive Cancer Center is a cancer research and treatment center located in Buffalo, New York. Founded by surgeon Roswell Park in 1898, the center was the first in the United States to specifically focus on cancer research. The ...
in
Buffalo, New York Buffalo is the second-largest city in the U.S. state of New York (behind only New York City) and the seat of Erie County. It is at the eastern end of Lake Erie, at the head of the Niagara River, and is across the Canadian border from South ...
as director of its breast surgery department, focusing on treatment of breast cancer and research into how it is caused and stimulated by hormones. At the time, radical mastectomy was the standard method of treatment used for 90% of cases until the 1970s, involving a
surgical procedure Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pat ...
where the entire affected breast,
axilla The axilla (also, armpit, underarm or oxter) is the area on the human body directly under the shoulder joint. It includes the axillary space, an anatomical space within the shoulder girdle between the arm and the thoracic cage, bounded superior ...
ry
lymph node A lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system. A large number of lymph nodes are linked throughout the body by the lymphatic vessels. They are major sites of lymphocytes that inclu ...
s and underlying chest muscle (including the
pectoral muscles Pectoral muscles (colloquially referred to as "pecs") are the muscles that connect the front of the human chest with the bones of the upper arm and shoulder. This region contains four muscles that provide movements to the upper limbs or ribs. Pe ...
) were removed as soon as a
malignant tumor Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal ble ...
was found through a
biopsy A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist. The process involves extraction of sample cells or tissues for examination to determine the presence or extent of a diseas ...
. Dao's research showed that more conservative approaches in which the mastectomy was not performed immediately and in which much smaller portions of tissue were removed were just as effective as the radical approach. In 1974, Dao was the physician who performed a modified radical mastectomy for Rose Kushner, who was to become an effective patient activist in opposition to the more radical standard treatments for breast cancer. He endorsed her controversial 1975 book on the subject of breast cancer and its treatment, saying "Every woman in the United States should read this book."Barron H. Lerner (2003),
The breast cancer wars: hope, fear, and the pursuit of a cure in twentieth-century America
', Oxford University Press US, ,
By the time of his death, the prevailing standard was a two-step approach in which a patient takes time to consider treatment options with their physician after malignant tumors have been identified. He served at Roswell Park Comprehensive Cancer Center until 1988.


Personal

Dao was a resident of
Williamsville, New York Williamsville is a village in Erie County, New York, United States. The population was 5,423 at the 2020 census. The village is named after Jonas Williams, an early settler. It is part of the Buffalo–Niagara Falls Metropolitan Statistical ...
. He and his second wife, whom he married in 1954, had two daughters and two sons; he also had four children from a first marriage that ended in divorce. He died at age 88 on July 16, 2009, at Hospice Buffalo in
Cheektowaga, New York Cheektowaga () is a town in Erie County, New York, United States. As of the 2020 census, the town has grown to a population of 89,877. The town is in the north-central part of the county, and is an inner ring suburb of Buffalo. The town is the ...
due to
Pick's disease Frontotemporal dementia (FTD), or frontotemporal degeneration disease, or frontotemporal neurocognitive disorder, encompasses several types of dementia involving the progressive degeneration of frontal and temporal lobes. FTDs broadly present as ...
.


References

{{DEFAULTSORT:Dao, Thomas 1921 births 2009 deaths American surgeons Chinese emigrants to the United States University of Chicago staff Deaths from Pick's disease Deaths from dementia in New York (state) People from Williamsville, New York Scientists from Suzhou St. John's University, Shanghai alumni Soochow University (Suzhou) alumni