tRNA-splicing endonuclease subunit Sen2 is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that in humans is encoded by the ''TSEN2''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
tRNA splicing is a fundamental process required for cell growth and division. SEN2 is a subunit of the
tRNA splicing endonuclease, which catalyzes the removal of introns, the first step in tRNA splicing (Paushkin et al., 2004).
upplied by OMIMref name="entrez"/>
Interactions
TSEN2 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with
TSEN34
tRNA-splicing endonuclease subunit Sen34 is an enzyme that in humans is encoded by the ''TSEN34'' gene.
tRNA splicing is a fundamental process required for cell growth and division. SEN34 is a subunit of the tRNA splicing endonuclease, which cata ...
and
TSEN15.
[
]
References
External links
GeneReviews/NCBI/NIH/UW entry on Pontocerebellar Hypoplasia Type 2 and Type 4
Further reading
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