Streptomyces rimosus
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''Streptomyces rimosus'' is a bacterium species in the genus '' Streptomyces''.


Uses

The antibiotics
oxytetracycline Oxytetracycline is a broad-spectrum tetracycline antibiotic, the second of the group to be discovered. Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins. Without these proteins, the bacteria cannot g ...
and
tetracycline Tetracycline, sold under various brand names, is an oral antibiotic in the tetracyclines family of medications, used to treat a number of infections, including acne, cholera, brucellosis, plague, malaria, and syphilis. Common side effects in ...
are produced in cultures of ''S. rimosus''. Paromomycin has also been isolated from cultures of ''S. rimosus''.


Polyketide synthesis

''S. rimosus''s oxytetracycline
polyketide synthase Polyketides are a class of natural products derived from a precursor molecule consisting of a chain of alternating ketone (or reduced forms of a ketone) and methylene groups: (-CO-CH2-). First studied in the early 20th century, discovery, biosynth ...
acyl carrier protein The acyl carrier protein (ACP) is a cofactor of both fatty acid and polyketide Polyketides are a class of natural products derived from a precursor molecule consisting of a chain of alternating ketone (or reduced forms of a ketone) and methylene ...
differs from most ACPs by having a C-terminus extension.


References


External links


Type strain of ''Streptomyces rimosus'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
rimosus {{Streptomyces-stub