Synthon is a Dutch multinational that produces generic human drugs. The company was founded in 1991 by Jacques Lemmens and Huub Sanders, two organic chemists of the Radboud University Nijmegen. Synthon is active in the

Netherlands ) , anthem = ( en, "William of Nassau") , image_map = , map_caption = , subdivision_type = Sovereign state , subdivision_name = Kingdom of the Netherlands , established_title = Before independence , established_date = Spanish Netherl ...

, the

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, the

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and

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with about 1,500 employees. The company is headquartered in

Nijmegen Nijmegen (;; Spanish and it, Nimega. Nijmeegs: ''Nimwèège'' ) is the largest city in the Dutch province of Gelderland and tenth largest of the Netherlands as a whole, located on the Waal river close to the German border. It is about 6 ...

. Medications made by Synthon include: *

Simvastatin Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. It is also used to decrease the risk of heart ...

(A statin) * Tamsulosin (An

alpha blocker Alpha (uppercase , lowercase ; grc, ἄλφα, ''álpha'', or ell, άλφα, álfa) is the first letter of the Greek alphabet. In the system of Greek numerals, it has a value of one. Alpha is derived from the Phoenician letter aleph , which ...

for the symptomatic treatment of benign prostatic hyperplasia) *

Paroxetine Paroxetine, sold under the brand names Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder ...

(An

antidepressant Antidepressants are a class of medication used to treat major depressive disorder, anxiety disorders, chronic pain conditions, and to help manage addictions. Common side-effects of antidepressants include dry mouth, weight gain, dizziness, hea ...

) * Fluvoxamine (An

) The products are marketed by partners of the company. The name Synthon is not mentioned on the packaging.

History

In 2007 the company started developing biopharmaceuticals. In May 2012 Synthon announced that it bought the

Biolex Biolex Therapeutics was a biotechnology firm in the Research Triangle Park, Research Triangle of North Carolina which was founded in 1997 and raised $190 million from investors. It filed for Chapter 7, Title 11, United States Code, Chapter 7 ba ...

LEX System for manufacturing biopharmaceuticals in Lemna. The sale also included two

preclinical In drug development, preclinical development, also termed preclinical studies or nonclinical studies, is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug ...

biologics made with the LEX System, BLX-301, a humanized and glyco-optimized anti- CD20 antibody for non-Hodgkin's B-cell lymphoma and other

B-cell B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. B cells produce antibody molecules which may be either secreted o ...

malignancies and BLX-155, a direct-acting thrombolytic. The financial terms of the sale were not disclosed.Biolex Sells LEX System to Synthon and Initiates Sale of Locteron(R)
Press Release: Biolex Therapeutics – Mon, May 7, 2012.

References

External links

* {{Authority control 1991 establishments in the Netherlands Dutch brands Generic drug manufacturers Life sciences industry Pharmaceutical companies established in 1991 Pharmaceutical companies of the Netherlands Biotechnology companies established in 2007 Companies based in Gelderland