Susan Adele Greenfield
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Susan Adele Greenfield, Baroness Greenfield, (born 1 October 1950) is an English scientist, writer, broadcaster and member of the House of Lords (since 2001). Her research has focused on the treatment of Parkinson's disease and
Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
. She is also interested in the neuroscience of consciousness and the impact of technology on the brain. Greenfield is a senior research fellow at
Lincoln College, Oxford Lincoln College (formally, The College of the Blessed Mary and All Saints, Lincoln) is one of the constituent colleges of the University of Oxford, situated on Turl Street in central Oxford. Lincoln was founded in 1427 by Richard Fleming, the ...
;University of Oxford> Department of Pharmacology> Baroness Susan Greenfield
Accessed 12 June 2015.
she was a professor of Synaptic Pharmacology. Greenfield was chancellor of
Heriot-Watt University Heriot-Watt University ( gd, Oilthigh Heriot-Watt) is a public research university based in Edinburgh, Scotland. It was established in 1821 as the School of Arts of Edinburgh, the world's first mechanics' institute, and subsequently granted univ ...
in Edinburgh between 2005 and 2013. From 1998 to 2010, she was director of the Royal Institution of Great Britain. In September 2013, she co-founded the biotech company Neuro-bio Ltd, where she is chief executive officer.


Education

Greenfield's mother, Doris (née Thorp), was a dancer and a Christian, and her father, Reginald Myer Greenfield, was an electrician who was the son of a first-generation Yiddish-speaking Jewish immigrant from Austria; her grandmothers never spoke and she said of them, "the prejudice was equally vociferous on both sides". She attended the
Godolphin and Latymer School The Godolphin and Latymer School is an independent day school for girls in Hammersmith, West London. The school motto is an ancient Cornish phrase, ''Francha Leale Toge'', which translates as "free and loyal art thou". The school crest inclu ...
, where she took A levels in Latin, Greek and ancient history, and maths. The first member of her immediate family to go to university, she was initially admitted to St Hilda's College to read Philosophy and Psychology, but changed course and graduated with a first-class degree in experimental psychology. As a Senior Scholar at
St Hugh's College, Oxford St Hugh's College is one of the constituent colleges of the University of Oxford. It is located on a site on St Margaret's Road, to the north of the city centre. It was founded in 1886 by Elizabeth Wordsworth as a women's college, and accepte ...
, she completed her DPhil degree in 1977 under the supervision of Anthony David Smith on the ''Origins of
acetylcholinesterase Acetylcholinesterase (HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme Enzymes () are proteins that a ...
in cerebrospinal fluid''. She then held a junior research fellowship at Green College, Oxford between 1981 and 1984.


Career

Greenfield's research is focused on brain physiology, particularly on the brain mechanisms of
Parkinson's Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...
and
Alzheimer's Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As t ...
diseases. She is also known for her role in popularising science. Greenfield has written several books about the brain, regularly gives public lectures, and appears on radio and television. Since 1976, Greenfield has published approximately 200 papers in peer-reviewed journals, including studies on brain mechanisms involved in addiction and reward, relating to
dopamine Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic compound, organic chemical of the catecholamine and phenethylamine families. Dopamine const ...
systems and other neurochemicals. She investigated the brain mechanisms underlying attention deficit hyperactivity disorder (
ADHD Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by excessive amounts of inattention, hyperactivity, and impulsivity that are pervasive, impairing in multiple contexts, and otherwise age-inapp ...
) as well as the impact of environmental enrichment. In 1994, she was the first woman to give the Royal Institution Christmas Lectures, then sponsored by the BBC. Her lectures were titled "Journey to the centre of the brain". She was appointed Director of the
Royal Institution The Royal Institution of Great Britain (often the Royal Institution, Ri or RI) is an organisation for scientific education and research, based in the City of Westminster. It was founded in 1799 by the leading British scientists of the age, inc ...
in 1998. The post was abolished in 2010. The Royal Institution had found itself in a financial crisis following a £22m development programme led by Greenfield and the Board. The project ended £3 million in debt. Greenfield subsequently announced that she would be taking her employers to an employment tribunal and her claim would include discrimination. The case was settled out of court. Greenfield's two main positions at Oxford were Tutorial Fellow in Medicine at Lincoln College Oxford, and Professor of Synaptic Pharmacology. Between 1995 and 1999, she gave public lectures as
Gresham Professor of Physic The Professor of Physic (the term for medicine at the time the post was created in 1597) at Gresham College in London, England, gives free educational lectures to the general public on medicine, health and related sciences. The college was founded ...
in London. Greenfield was Adelaide's
Thinker in Residence Thinkers in Residence is a program in Adelaide, South Australia, designed to bring leaders in their fields to work with the South Australian community and government in developing new ideas and approaches to problem-solving, and to promote South A ...
for 2004 and 2005. As a result of her recommendations, South Australian Premier Mike Rann made a major funding commitment, backed by the State and Federal Governments and the private sector, to establish the
Royal Institution of Australia The Royal Institution of Australia (RiAus) is a national scientific not-for-profit organisation with a mission to "bring science to people and people to science". It opened in October 2009. Concept The concept of a Royal Institution of Austral ...
and the Australian Science Media Centre in Adelaide. She has explored the relevance of neuroscience knowledge to education and has used the phrase "mind change", an umbrella term comparable to "climate change", encompassing diverse issues involved in the impact of the 21st-century environment on the brain. In 2013 she co-founded the biotech company Neuro-bio Ltd which develops diagnostic tests and therapeutics for
Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
. The company has found that the C terminus of
acetylcholinesterase Acetylcholinesterase (HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme Enzymes () are proteins that a ...
can be cleaved and that the resulting peptide can kill neurons; the company has also found that a
cyclic peptide Cyclic peptides are polypeptide chains which contain a circular sequence of bonds. This can be through a connection between the amino and carboxyl ends of the peptide, for example in cyclosporin; a connection between the amino end and a side chai ...
analogue could prevent that neuronal death. The company raised around $4 million in 2017.


Politics

Greenfield sits in the Parliament of the United Kingdom in the House of Lords as a
crossbencher A crossbencher is an independent or minor party member of some legislatures, such as the British House of Lords and the Parliament of Australia. They take their name from the crossbenches, between and perpendicular to the government and oppositi ...
, having no formal political affiliation. Records of Greenfield's activity in the House of Lords indicate abstention on a range of issues. She has spoken on a variety of topics, including education, drugs, and economic empowerment for women.


Books

In 2013, Greenfield published a dystopian science-fiction novel, ''2121: A Tale from the Next Century'', telling the story of videogame-playing hedonists and their conflict with "Neo-Puritans". In 2014, Greenfield published a
popular science ''Popular Science'' (also known as ''PopSci'') is an American digital magazine carrying popular science content, which refers to articles for the general reader on science and technology subjects. ''Popular Science'' has won over 58 awards, incl ...
book called ''Mind Change: How Digital Technologies are Leaving their Mark on our Brains,'' describing her ideas about the impact of digital technology.


Impact of digital technology controversy

Greenfield has expressed concerns that internet usage may modify the brain structures of youngsters. She noted that Public Health England had related social networking and multiplayer online games to "lower levels of wellbeing", and believed that evidence pointed to a "
dose response Dose or Dosage may refer to: Music * ''Dose'' (Gov't Mule album), 1998 * ''Dose'' (Latin Playboys album) * ''Dosage'' (album), by the band Collective Soul * "Dose" (song), a 2018 song by Ciara * "Dose", song by Filter from the album '' Short ...
" relationship, "where each additional hour of viewing increases the likelihood of experiencing socio-emotional problems". She believed this raised questions about where to draw the boundaries between beneficial and harmful use of such technology, saying that "it would be surprising if many hours per day of screen activity did not influence this neuroplasticity".


Honours

As of 2016, Greenfield has 32 honorary degrees; has received awards including the Royal Society's Michael Faraday Prize. She has been elected to an Honorary Fellowship of the Royal College of Physicians and the London Science Museum. In 2006 she was made an Honorary Fellow of the British Science Association and was the Honorary Australian of the Year. In January 2000, Greenfield received a CBE for her contribution to the public understanding of science. Later that year, she was named Woman of the Year by '' The Observer''. In 2001, she became a
Life Peer In the United Kingdom, life peers are appointed members of the peerage whose titles cannot be inherited, in contrast to hereditary peers. In modern times, life peerages, always created at the rank of baron, are created under the Life Peerages ...
under the House of Lords Appointments Commission system, as Baroness Greenfield, of Ot Moor, Oxfordshire. Like the other people's peers she was self-nominated. In 2003, she was appointed a Knight of the Legion of Honour by the
French Government The Government of France ( French: ''Gouvernement français''), officially the Government of the French Republic (''Gouvernement de la République française'' ), exercises executive power in France. It is composed of the Prime Minister, who ...
. In 2010 she was awarded the Australian Society for Medical Research Medal. She received the British Inspiration award for Science and Technology in 2010.


Patronage

She is a patron of Alzheimer's Research UK and of Dignity in Dying. She is a founder and trustee of the charity Science for Humanity, a network of scientists, researchers and technologists that collaborates with not-for-profit organisations to create practical solutions to the everyday problems of developing communities.


Personal life

Greenfield was married to the University of Oxford Professor Peter Atkins from 1991 until their divorce in 2005.


Bibliography

* * * * * * * * * *


References


Further reading


Screen culture may be changing our brains Australian Broadcasting Corporation: The 7.30 Report
19 March 2009.
'Stumbling into a Powerful Technology' (Address to the House of Lords)
20 April 2006.


External links

* * {{DEFAULTSORT:Greenfield, Susan Greenfield, Baroness 1950 births 20th-century British biologists 20th-century British women scientists 21st-century British biologists 21st-century British women scientists Academics of Heriot-Watt University Alumni of St Hilda's College, Oxford Alzheimer's disease researchers British women biologists Chevaliers of the Légion d'honneur Commanders of the Order of the British Empire Crossbench life peers Directors of the Royal Institution English people of Austrian-Jewish descent Fellows of Green College, Oxford Fellows of Lincoln College, Oxford Fellows of the Royal College of Physicians Life peeresses created by Elizabeth II Fullerian Professors of Physiology Recipients of the Legion of Honour Living people Jewish Austrian writers Jewish scientists Jewish women scientists Jewish women writers Jewish British politicians Jewish women politicians Parkinson's disease researchers People educated at Godolphin and Latymer School People's peers People from Chiswick Professors of Gresham College British neuroscientists British women neuroscientists 20th-century English women writers 21st-century English women writers Presidents of the Classical Association