Steven M. Weinreb (born May 10, 1941) is an American chemist and is a professor of chemistry at

Pennsylvania State University The Pennsylvania State University (Penn State or PSU) is a Public university, public Commonwealth System of Higher Education, state-related Land-grant university, land-grant research university with campuses and facilities throughout Pennsylvan ...

in United States. Together with Steven Nahm, he developed the

Weinreb ketone synthesis The Weinreb–Nahm ketone synthesis is a chemical reaction used in organic chemistry to make carbon–carbon bonds. It was discovered in 1981 by Steven M. Weinreb and Steven Nahm as a method to synthesize ketones. The original reaction involved ...

, which allows for mono-addition of an

organometallic Organometallic chemistry is the study of organometallic compounds, chemical compounds containing at least one chemical bond between a carbon atom of an organic molecule and a metal, including alkali, alkaline earth, and transition metals, and so ...

reagent such as a

Grignard reagent A Grignard reagent or Grignard compound is a chemical compound with the general formula , where X is a halogen and R is an organic group, normally an alkyl or aryl. Two typical examples are methylmagnesium chloride and phenylmagnesium bromide ...

or organolithium reagent to an amide. Weinreb received his PhD for work with Marshall Gates at the University of Rochester in 1967. After post-docs with Gilbert Stork and George H. Buchi, he worked at

Fordham University Fordham University () is a Private university, private Jesuit universities, Jesuit research university in New York City. Established in 1841 and named after the Fordham, Bronx, Fordham neighborhood of the The Bronx, Bronx in which its origina ...

. He joined the Pennsylvania State University in 1978, where he holds the Russell and Mildred Marker Professor of Natural Products Chemistry chair.

References

* 1941 births University of Rochester alumni Pennsylvania State University faculty 21st-century American chemists Living people {{chemist-stub