Sherine Obare
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Sherine O. Obare is the dean of the Joint School of Nanoscience and Nanoengineering at the University of North Carolina at Greensboro and North Carolina Agricultural and Technical State University. She works on nanomaterials for sensing and drug delivery.


Early life and education

Obare spent her childhood in Germany, where she attended a British high school. She studied chemistry, mathematics and physics. She majored in engineering, but decided to focus on chemistry because of her college roommate. She eventually began her bachelor's degree in chemistry at
West Virginia State University West Virginia State University (WVSU) is a public historically black, land-grant university in Institute, West Virginia. Founded in 1891 as the West Virginia Colored Institute, it is one of the original 19 land-grant colleges and universities ...
and graduated in 1998. She applied for a job at the United States Environmental Protection Agency, but was convinced by her professor to she would enjoy graduate school. She joined the University of South Carolina for her doctoral studies and earned her PhD in 2002. She worked under the supervision of Catherine J. Murphy. With Murphy, Obare developed a new approach to fabricate polystyrene and silica coated gold nanorods as templates for hollow
nanotube A nanotube is a nanometer-scale hollow tube-like structure. Kinds of nanotubes * BCN nanotube, composed of comparable amounts of boron, carbon, and nitrogen atoms * Boron nitride nanotube, a polymorph of boron nitride * Carbon nanotube, includes g ...
s. Hollow
nanotube A nanotube is a nanometer-scale hollow tube-like structure. Kinds of nanotubes * BCN nanotube, composed of comparable amounts of boron, carbon, and nitrogen atoms * Boron nitride nanotube, a polymorph of boron nitride * Carbon nanotube, includes g ...
s are useful for drug delivery, cell and enzyme transplantation, removal of contaminated waste and gene therapy. To create the gold nanorods, Obare used nanoparticles as a seed in a growth solution that contained cetyltrimethylammonium bromide,
sodium hydroxide Sodium hydroxide, also known as lye and caustic soda, is an inorganic compound with the formula NaOH. It is a white solid ionic compound consisting of sodium cations and hydroxide anions . Sodium hydroxide is a highly caustic base and alkali ...
and
ascorbic acid Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits and vegetables, also sold as a dietary supplement and as a topical 'serum' ingredient to treat melasma (dark pigment spots) an ...
at a controlled pH (3.5). She demonstrated that gold nanoparticles functionalised with
1,10-phenanthroline 1,10-Phenanthroline (phen) is a heterocyclic organic compound. It is a white solid that is soluble in organic solvents. The 1,10 refer to the location of the nitrogen atoms that replace CH's in the hydrocarbon called phenanthrene. Abbreviated ...
could be used to sense lithium ions in solution. The ligands of
1,10-phenanthroline 1,10-Phenanthroline (phen) is a heterocyclic organic compound. It is a white solid that is soluble in organic solvents. The 1,10 refer to the location of the nitrogen atoms that replace CH's in the hydrocarbon called phenanthrene. Abbreviated ...
bind to the lithium ions, forming a complex that causes the
nanoparticles A nanoparticle or ultrafine particle is usually defined as a particle of matter that is between 1 and 100 nanometres (nm) in diameter. The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 1 ...
to aggregate. Obare explored several ligands, including dipyrido phenazine (DPPZ) which changes colour when it binds to lithium ions. The nanorods can form liquid crystalline phases. Obare was a Camille and Henry Dreyfus Foundation fellow at Johns Hopkins University working under the supervision of Gerald Meyer.


Career

In 2004 Obare joined Western Michigan University as an assistant professor and promoted to tenure in 2009. She also works on nanomaterials for drug delivery and chemical sensing. She investigated fluorescent chemosensors to monitor for
organophosphorous In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure , a central phosphate molecule with alkyl or aromatic substituents. They can be considered ...
.
Organophosphorous In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure , a central phosphate molecule with alkyl or aromatic substituents. They can be considered ...
can inhibit cholinesterase and can have severe environmental and health impacts. Obare was awarded an National Science Foundation CAREER Award in 2006. This allowed her to develop multi-electron transfer catalysts. Obare is interested in multi-electron transfer. She has investigated electron transfer from heme-functionalised titanium dioxide to organohalide pollutants. She demonstrated that organohalides degrade via multi-electron pathways. She has explored new techniques to synthesise and characterise monodisperse nanoparticles. The nanoparticles can be used to detect bacteria in waterborne diseases. Obare was appointed associate dean at Western Michigan University in 2015. She was responsible for research, education, diversity and global engagement across the university. She believes that early authentic research is essential for underrepresented groups to gain rational view of the world. From 2017 Obare served as Associate Vice President for Research at Western Michigan University. Obare is an associate editor for the ''
Journal of Nanomaterials This is a list of academic journals published by Hindawi Publishing Corporation, Hindawi. A B C D E G H I J L M N O P Q R S T U V W References {{Reflist External linksList of journals published by ...
''. She moved to the University of North Carolina at Greensboro as dean of the Joint School of Nanoscience and Nanoengineering. Obare chairs the American Chemical Society Award for Incorporation of Sustainability into the Curriculum.


Awards and honours

*2006 National Science Foundation CAREER Award *2007 American Chemical Society Dreyfus Lectureship Award *2009 Haenicke Institute for Global Education International Faculty Development Award *2009 International Union of Pure and Applied Chemistry Young Observer Award *2009 National Science Foundation Materials Grant *2010 American Competitiveness and Innovation (ACI) Fellowship *2010 NOBCChE Lloyd N. Ferguson Young Scientist Award *2010 Science Spectrum Magazine Trailblazer Award *2012 National Organization for the Professional Advancement of Black Chemists and Chemical Engineers President’s Award


Books

* 2018 The Power and Promise of Early Research


References

{{DEFAULTSORT:Obare, Sherine African-American chemists American chemists 21st-century American chemists American women chemists Women physical chemists University of Southern California alumni West Virginia State University alumni Western Michigan University faculty University of North Carolina faculty Year of birth missing (living people) Living people American women academics 21st-century African-American women 21st-century African-American scientists 21st-century American women scientists